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Enterosgel Intestinal Toxin Binding Adsorbent Gel - 90g

Enterosgel Intestinal Toxin Binding Adsorbent Gel - 90g

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  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Binds gut toxins and pathogens without entering the bloodstream
  • ✔️ Suitable for adults and children from one year old
  • ✔️ Relieves acute diarrhoea including traveller's diarrhoea
  • ✔️ Does not slow gut motility, reducing rebound constipation risk
  • ✔️ 90g tube provides a full short-term treatment course

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What Is Enterosgel for Diarrhoea and How Can It Help?

 

Diarrhoea can strike at the worst possible moments — whether you're travelling, recovering from a stomach bug, or dealing with a flare-up linked to food intolerance. Enterosgel for diarrhoea is an oral intestinal adsorbent gel that works differently from most over-the-counter remedies. Rather than slowing down gut movement, it targets the root cause by binding harmful substances directly inside the digestive tract. The 90g tube gives you enough gel for a full short-term course, making it a practical option to keep at home or pack for travel. If you're looking for other gut-related products, you can browse our full diarrhoea relief range at Cured Pharmacy.

Enterosgel contains polymethylsiloxane polyhydrate, an organosilicon compound that has been used clinically in Europe for several decades. It is available over the counter in the UK without a prescription and is suitable for adults and children from the age of one year. The gel has a neutral taste and mixes easily with water, which makes it more tolerable than some tablet-based alternatives — particularly for those who struggle to swallow capsules.

 

How Does Enterosgel Work Inside the Gut?

 

The mechanism behind Enterosgel is adsorption — not absorption. That distinction matters. The gel acts like a sponge within the intestinal lumen, attracting and binding toxins, pathogenic bacteria, viruses, and allergens to its porous surface. Once bound, these substances cannot pass through the gut wall into the bloodstream. They are then carried out of the body naturally through the stool.

  • The gel is not absorbed into the bloodstream — it stays entirely within the gastrointestinal tract.
  • It binds a wide range of harmful substances including bacterial toxins, rotavirus particles, and food allergens.
  • It does not interfere with gut motility, so it does not cause the rebound constipation sometimes associated with loperamide.
  • It is excreted unchanged, carrying bound toxins out of the body within hours.

 

Who Should Use Enterosgel and Is It Right for You?

 

Enterosgel is suitable for a broad range of people experiencing acute diarrhoea or gut discomfort linked to toxin exposure. It is particularly well-suited to those who prefer a non-pharmacological approach to managing gut symptoms, or who cannot tolerate loperamide. It is also used by people managing food intolerances, traveller's diarrhoea, or antibiotic-associated gut disturbance.

  • Adults and children aged one year and over with acute diarrhoea
  • Travellers seeking a portable, easy-to-use gut remedy
  • People with food intolerances or allergic gut reactions
  • Those recovering from gastrointestinal infections caused by bacteria or viruses

It is not suitable for people with known intestinal obstruction or those who are hypersensitive to any component of the gel. Always read the patient information leaflet before use.

 

How Does Enterosgel Compare to Other Diarrhoea Treatments?

 

Feature Enterosgel 90g Loperamide (e.g. Imodium)
Mechanism Adsorbs toxins and pathogens in the gut Slows gut motility via opioid receptors
Absorbed into bloodstream? No Yes (minimally)
Suitable for children from age 1? Yes No (not under 12 without medical advice)
Risk of rebound constipation Low Possible

 

How Should You Store Enterosgel and Is It Suitable Long-Term?

 

Enterosgel for diarrhoea is intended for short-term use during acute episodes. It is not designed as a long-term daily supplement. Store the tube below 25°C, away from direct sunlight, and keep it out of reach of children. Do not freeze the gel, as this may alter its texture and effectiveness. Once opened, use within the period stated on the packaging.

If you are managing ongoing gut symptoms such as irritable bowel syndrome, you may also find it helpful to explore our IBS and cramps collection for complementary products. Always speak to your GP or pharmacist if your symptoms are recurrent or do not improve within 48 hours of starting treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Enterosgel Intestinal Toxin Binding Adsorbent Gel 90g specifications
Treatment category Antidiarrhoeal / Intestinal adsorbent
Mechanism of action Adsorbs toxins, pathogens, and allergens in the gastrointestinal tract
Effective for Acute diarrhoea, traveller's diarrhoea, food intolerance-related gut symptoms
Suitable for Adults and children aged 1 year and over
Active ingredient Polymethylsiloxane polyhydrate
Pack size 90g tube
UK classification General Sale / Over-the-counter (OTC)
Drug class Intestinal adsorbent
Preparation Oral gel
Route of administration Oral

Specifications of Enterosgel Intestinal Toxin Binding Adsorbent Gel 90g

 

What Is Enterosgel Intestinal Adsorbent Gel and What Is It Used For?

 

Enterosgel Intestinal Toxin Binding Adsorbent Gel is an oral gel used to treat acute diarrhoea in adults and children. It contains polymethylsiloxane polyhydrate, an organosilicon compound that acts as an intestinal adsorbent. The gel is taken by mouth, mixed with water, and works entirely within the gastrointestinal tract without entering the bloodstream. It is used to relieve diarrhoea caused by infections, food intolerances, traveller's diarrhoea, and antibiotic-associated gut disturbance. According to NHS guidance, most cases of diarrhoea in adults clear up within two to four days without treatment, but an adsorbent gel can help manage symptoms and reduce the duration of discomfort.

 

What Do You Need to Know Before Using Enterosgel?

 

Before using Enterosgel, it is important to check whether it is appropriate for you. Read the following contraindications and warnings carefully.

  • Do not use if you have a known intestinal obstruction or ileus.
  • Do not use if you are hypersensitive to polymethylsiloxane polyhydrate or any other ingredient in the gel.
  • Use with caution in people with severe constipation or reduced gut motility.
  • If you have blood in your stool, a high fever, or signs of severe dehydration, seek medical attention before using this product.
  • Consult your doctor before use if you are pregnant or breastfeeding.

Enterosgel may reduce the absorption of other oral medicines taken at the same time. The following interaction guidance applies:

  • Take all other oral medicines at least 1–2 hours before or after Enterosgel.
  • This includes prescription medicines, vitamins, and supplements — you can browse our vitamins and supplements range for products that may need to be timed separately.
  • No specific drug interactions have been formally documented, but the adsorptive nature of the gel means co-administration with other medicines should be avoided.

 

How Should You Use Enterosgel Correctly?

 

Always use Enterosgel exactly as described in the patient information leaflet or as directed by your pharmacist. Do not exceed the recommended dose. It is important to maintain adequate fluid intake while using this product, as diarrhoea can cause dehydration — the NHS recommends drinking plenty of fluids such as water or diluted squash to replace lost fluids.

  1. Measure the correct dose using the markings on the tube or a clean spoon.
  2. Mix the gel thoroughly with half a glass of water (approximately 100–150ml).
  3. Drink the mixture immediately after preparation.
  4. Take 1–2 hours before or after meals and other medicines.
  5. Drink additional water or fluids throughout the day to stay hydrated.
  6. Continue for the recommended duration — typically 3–5 days for acute diarrhoea.
Age Group Dose Frequency
Adults and children over 14 years 1 tablespoon (15g) Three times daily
Children aged 5–14 years 1 dessertspoon (10g) Three times daily
Children aged 1–4 years 1 teaspoon (5g) Three times daily

 

What Are the Possible Side Effects of Enterosgel?

 

Like all medicines, Enterosgel can cause side effects, although not everyone experiences them. Most side effects are mild and short-lived. If you experience any side effect that concerns you, stop use and speak to your pharmacist or GP.

Common side effects:

  • Constipation — particularly if the gel is taken without sufficient fluid intake
  • Nausea — usually mild and transient

Less common side effects:

  • Feeling of fullness or bloating
  • Aversion to the texture of the gel in some users

There are no known serious adverse effects associated with Enterosgel when used as directed. However, if you develop signs of an allergic reaction — such as rash, swelling, or difficulty breathing — stop use immediately and seek emergency medical attention.

 

How Should You Store Enterosgel Safely?

 

Correct storage helps maintain the quality and effectiveness of the gel. Follow these instructions:

  • Store below 25°C in a cool, dry place.
  • Do not freeze — freezing may alter the gel's consistency and reduce its effectiveness.
  • Keep the tube tightly closed when not in use.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the tube.
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy.

If you are travelling and need to manage gut health on the go, you may also find useful products in our travel health collection, which includes rehydration salts and other digestive aids.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Enterosgel online in the UK?

You can buy Enterosgel Intestinal Toxin Binding Adsorbent Gel 90g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter product. Simply add it to your basket and it will be dispatched from our registered UK pharmacy.

How does Enterosgel work in the body?

Enterosgel works through a process called adsorption — its porous gel structure attracts and binds toxins, bacteria, viruses, and allergens within the intestinal lumen. The gel itself is not absorbed into the bloodstream; it remains entirely within the gut. Once it has bound the harmful substances, it is excreted naturally through the stool, taking those substances with it.

How do I use Enterosgel step by step?

Measure the correct dose from the tube, mix it thoroughly with approximately 100–150ml of water, and drink the mixture straight away. Take it 1–2 hours before or after meals and any other medicines you are using. Make sure you drink plenty of additional fluids throughout the day to stay hydrated, as diarrhoea can cause significant fluid loss.

What is the correct dose of Enterosgel for adults?

The standard adult dose is one tablespoon (15g) taken three times daily. This equates to 45g per day from the 90g tube, giving you approximately two days' supply at full adult dosing. Do not exceed the recommended dose without speaking to a pharmacist or doctor first.

Can children use Enterosgel safely?

Yes, Enterosgel is suitable for children from the age of one year, which makes it one of the few gut adsorbent products available for very young children. The dose is lower than for adults — children aged 1–4 years take one teaspoon (5g) three times daily, while children aged 5–14 years take one dessertspoon (10g) three times daily. Always follow the patient information leaflet or ask your pharmacist if you are unsure about the correct dose for your child.

What is the best time to take Enterosgel?

Enterosgel should be taken 1–2 hours before or after meals and other medicines to avoid interfering with nutrient or drug absorption. Spacing doses evenly throughout the day — for example morning, midday, and evening — helps maintain a consistent adsorbent effect in the gut. Consistency with timing is more important than taking it at any specific hour.

What are the side effects of Enterosgel and how do I manage them?

The most commonly reported side effects are constipation and nausea, both of which are generally mild. To reduce the risk of constipation, make sure you drink plenty of water alongside each dose. If nausea occurs, try taking the gel with a larger volume of water or after a light snack. If side effects persist or worsen, speak to your pharmacist.

Who is eligible to use Enterosgel?

Enterosgel is suitable for adults and children aged one year and over who are experiencing acute diarrhoea. It is not suitable for people with intestinal obstruction or known hypersensitivity to any of its ingredients. Pregnant or breastfeeding women should consult their doctor before use, and anyone with blood in their stool or a high fever should seek medical advice before starting treatment.

What happens if I miss a dose of Enterosgel?

If you miss a dose, simply take it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case skip the missed one and carry on as normal. Do not double up doses to compensate for a missed one. Missing a single dose is unlikely to significantly affect your recovery, provided you continue to stay well hydrated.

How long can you use Enterosgel for?

Enterosgel is intended for short-term use during acute episodes of diarrhoea, typically for 3–5 days. If your symptoms have not improved within 48 hours, or if they worsen at any point, you should seek medical advice rather than continuing to self-treat. It is not designed for long-term daily use without medical supervision.

Can I use Enterosgel for traveller's diarrhoea?

Yes, Enterosgel is commonly used for traveller's diarrhoea, which is typically caused by exposure to unfamiliar bacteria or food contaminants. Its compact 90g tube makes it easy to pack in hand luggage or a travel bag. You can also find other useful products for gut health abroad in our travel health collection.

Does Enterosgel interact with other medicines?

Because Enterosgel is an adsorbent gel, it has the potential to bind to other oral medicines taken at the same time, reducing their absorption and effectiveness. To avoid this, always take other medicines at least 1–2 hours before or after Enterosgel. This applies to prescription medicines, over-the-counter products, and supplements alike.

What are the alternatives to Enterosgel for diarrhoea?

Common alternatives include loperamide (sold as Imodium), which slows gut motility, and oral rehydration salts such as Dioralyte, which replace lost fluids and electrolytes. Unlike loperamide, Enterosgel does not slow gut movement — it works by binding toxins instead. You can explore the full range of options in our diarrhoea collection to find the most suitable product for your situation.

Is Enterosgel suitable during pregnancy?

Enterosgel is not absorbed into the bloodstream, which means systemic exposure to the active ingredient is not expected. However, there is limited clinical data specifically in pregnant women, so you should always consult your GP or midwife before using any medicine during pregnancy. Do not self-treat without professional guidance if you are pregnant.

What does the latest research say about Enterosgel?

Published clinical studies have examined Enterosgel's use in acute infectious diarrhoea, antibiotic-associated diarrhoea, and irritable bowel syndrome, with results generally supporting its tolerability and adsorbent efficacy. Research has also explored its potential role in managing gut permeability and allergen-related gut symptoms. While the evidence base is growing, Enterosgel is currently best established as a short-term treatment for acute diarrhoea in both adults and children.

How Should You Use Enterosgel Intestinal Adsorbent Gel?

Enterosgel is taken orally by mixing the gel with water before swallowing. It should never be taken dry or undiluted, as mixing it with water ensures the gel disperses properly and is easier to swallow. Always follow the dosage instructions in the patient information leaflet or as directed by your pharmacist.

What Is the Correct Dose of Enterosgel?

The dose of Enterosgel varies depending on the age of the person using it. Always use the lowest effective dose for the shortest time necessary. The table below summarises the recommended doses by age group and indication.

When Is the Best Time to Use Enterosgel?

Enterosgel should be taken 1–2 hours before or after meals and other oral medicines. This timing is important because the gel's adsorptive properties could otherwise bind to nutrients or medicines consumed at the same time, reducing their effectiveness. Spacing doses evenly throughout the day — for example, morning, midday, and evening — helps maintain a consistent effect within the gut.

If you are also taking prescription medicines or supplements, make sure to plan your Enterosgel doses around them. Consistency with timing matters more than taking it at a specific hour of the day.

How Long Can You Use Enterosgel For?

Enterosgel is designed for short-term use during acute episodes of diarrhoea, typically for 3–5 days. Most cases of acute diarrhoea in adults resolve within two to four days, so prolonged use beyond this period is generally not necessary. If your symptoms have not improved after 48 hours of use, or if they worsen at any point, stop using the product and seek medical advice promptly.

Long-term daily use of Enterosgel is not recommended without medical supervision, as extended use of intestinal adsorbents may affect the absorption of essential nutrients over time.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Enterosgel?

Enterosgel is generally well tolerated, and most people complete a short course without significant problems. However, as with any medicine, some side effects can occur. The most commonly reported ones are mild and usually resolve on their own without the need to stop treatment.

  • Constipation — particularly if insufficient water is taken alongside the gel
  • Nausea — usually mild and short-lived
  • Feeling of fullness or bloating in the abdomen

What Are the Less Common Side Effects of Enterosgel?

Less commonly, some people may notice a dislike of the gel's texture, which can make it harder to take consistently. This is not a medical side effect but can affect adherence to the recommended course. Mixing the gel thoroughly with a larger volume of water may help improve palatability.

  • Aversion to the texture or consistency of the gel
  • Mild abdominal discomfort in some users

What Are the Serious Side Effects of Enterosgel?

Serious side effects with Enterosgel are rare. However, you should stop using the product immediately and seek emergency medical attention if you experience any signs of an allergic reaction. These can include skin rash, itching, swelling of the face, lips, or throat, or difficulty breathing. Although hypersensitivity reactions to polymethylsiloxane polyhydrate are uncommon, they are possible in susceptible individuals.

If you develop worsening diarrhoea, blood in your stool, a high fever, or signs of severe dehydration — such as dizziness, reduced urination, or extreme thirst — stop use and contact your GP or call NHS 111 immediately.

What Should You Do If You Experience Side Effects?

For mild side effects such as constipation or nausea, increasing your fluid intake is usually the first step. Drink at least 1.5–2 litres of water per day while using Enterosgel, and consider spacing doses more evenly throughout the day. If constipation becomes uncomfortable, speak to your pharmacist, who may suggest a short-term laxative if appropriate.

If any side effect is severe, persistent, or unexpected, stop using the product and seek advice from your pharmacist or GP. Do not attempt to manage serious symptoms at home without professional guidance.

Can Enterosgel Interact With Other Medicines?

Enterosgel does not enter the bloodstream, so it does not cause the systemic drug interactions associated with many medicines. However, because it is an adsorbent gel, it can bind to other oral medicines taken at the same time, potentially reducing how much of those medicines is absorbed into your body. This applies to prescription medicines, over-the-counter products, and dietary supplements.

To avoid this interaction, always take other oral medicines at least 1–2 hours before or after your dose of Enterosgel. If you are unsure how to time your medicines, ask your pharmacist for personalised advice.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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