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Dulcolax Pico Liquid Laxative (Sodium Picosulfate) 5mg/5ml Oral Solution – 300ml

Dulcolax Pico Liquid Laxative (Sodium Picosulfate) 5mg/5ml Oral Solution – 300ml

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  • ✔️ Relieves occasional constipation within 6 to 12 hours
  • ✔️ Flexible liquid dose suitable for adults and children aged 4+
  • ✔️ Stimulant laxative action targets the colon directly
  • ✔️ Convenient 300ml bottle provides multiple doses
  • ✔️ Sodium picosulfate oral solution — easy to measure and swallow

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Is Sodium Picosulfate Liquid Right for Your Constipation?

 

Constipation is something most people experience at some point, and it can be genuinely uncomfortable — leaving you feeling bloated, sluggish, and frustrated. Sodium picosulfate liquid is the active ingredient in Dulcolax Pico Liquid Laxative, a well-established over-the-counter option for relieving occasional constipation in adults and children aged 4 and over. Each 5ml dose contains 5mg of sodium picosulfate, and the 300ml bottle gives you a generous supply for ongoing use when needed. If you're looking for a liquid alternative to tablets, this format is particularly useful for those who struggle to swallow solid medicines. You can browse our full range of constipation treatments if you'd like to compare your options.

Constipation is defined by the NHS as passing fewer than three stools per week, or stools that are hard, dry, and difficult to pass. It affects people of all ages and can be triggered by a low-fibre diet, dehydration, lack of physical activity, or certain medicines. Dulcolax Pico Liquid offers a flexible, dose-adjustable solution that can be tailored to your individual needs.

 

How Does Dulcolax Pico Liquid Work in the Body?

 

Understanding how a laxative works helps you use it more confidently. Dulcolax Pico Liquid is classified as a stimulant laxative. Here's what happens after you take a dose:

  • Sodium picosulfate is swallowed and passes through the stomach largely unchanged.
  • On reaching the colon, gut bacteria convert it into an active compound called BHPM (bis-(p-hydroxyphenyl)-pyridyl-2-methane).
  • BHPM stimulates the nerve endings in the colon wall, increasing muscular contractions (peristalsis).
  • This speeds up the movement of stool through the bowel and encourages a bowel motion, typically within 6 to 12 hours.
  • The liquid also has a mild effect on fluid absorption in the colon, helping to soften the stool.

Because the action is localised to the colon, sodium picosulfate is not significantly absorbed into the bloodstream, which is one reason it is considered suitable for short-term use in most healthy adults.

 

Who Is Dulcolax Pico Liquid Suitable For?

 

This product is designed for people who need short-term relief from occasional constipation. It is not intended as a long-term daily treatment. You might find it particularly helpful if:

  • You are an adult or child aged 4 years and over experiencing occasional constipation.
  • You prefer a liquid format over tablets or capsules.
  • You need a dose-adjustable laxative — the liquid allows you to fine-tune the amount you take.
  • You want a laxative that works overnight, taken at bedtime for a morning result.

It may also be useful before certain medical procedures where bowel preparation is required, but only under medical supervision in that context. If your constipation is linked to other digestive symptoms, it's worth exploring our IBS and cramps range for additional support.

 

How Does Dulcolax Pico Liquid Compare to Other Laxatives?

 

Not all laxatives work the same way. Here's a quick comparison to help you decide whether this product is the right fit for you.

Feature Dulcolax Pico Liquid (Sodium Picosulfate) Lactulose Oral Solution
Type of laxative Stimulant Osmotic
Onset of action 6–12 hours 24–48 hours
Suitable for children Yes, aged 4+ Yes, all ages (with guidance)
Dose flexibility Yes — adjustable liquid dose Yes — adjustable liquid dose

 

How Should You Store Dulcolax Pico Liquid?

 

Store Dulcolax Pico Liquid below 25°C, away from direct light and heat. Keep the bottle tightly closed when not in use, and always store it out of the sight and reach of children. Do not use the product after the expiry date printed on the label. Once opened, check the product leaflet for any specific in-use shelf-life guidance.

If you are managing multiple health conditions alongside constipation — for example, if you take diuretics or have a history of electrolyte imbalances — it is especially important to seek advice before starting any stimulant laxative. This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Dulcolax Pico Liquid Laxative (Sodium Picosulfate) 5mg/5ml Oral Solution – 300ml specifications
Treatment category Constipation relief
Mechanism of action Stimulant laxative — activates colonic peristalsis via bacterial conversion to BHPM
Effective Within 6–12 hours
Suitable for Adults and children aged 4 years and over
Active ingredient Sodium Picosulfate 5mg/5ml
Pack size 300ml
Strength 5mg/5ml
UK classification General Sale List (GSL) / Pharmacy (P) — check pack
Drug class Stimulant laxative
Preparation Oral solution
Route of administration Oral

Specifications of Dulcolax Pico Liquid Laxative (Sodium Picosulfate) 5mg/5ml Oral Solution – 300ml

 

What Is Dulcolax Pico Liquid and What Is It Used For?

 

Dulcolax Pico Liquid Laxative is an oral solution containing sodium picosulfate 5mg per 5ml. It belongs to a group of medicines called stimulant laxatives, which work by encouraging the bowel to contract and move stool along more efficiently. It is used to relieve occasional constipation in adults and children aged 4 years and over. The NHS describes constipation as a common condition that affects people of all ages, often caused by not eating enough fibre, not drinking enough fluids, or not exercising regularly. This product provides a flexible, liquid-format option for those who need short-term relief.

 

What Do You Need to Know Before Using Dulcolax Pico Liquid?

 

Before taking this medicine, read the following carefully. Do not use Dulcolax Pico Liquid if any of the following apply to you:

  • You are allergic to sodium picosulfate or any other ingredient in the product.
  • You have or suspect you have a bowel obstruction (ileus).
  • You have severe abdominal pain, nausea, or vomiting of unknown cause.
  • You are severely dehydrated.
  • You have a rare hereditary condition such as fructose intolerance (check excipients with your pharmacist).
  • You are a child under 4 years of age.

Talk to your doctor or pharmacist before use if you:

  • Are pregnant or breastfeeding — stimulant laxatives are not usually the first choice; the NHS recommends bulk-forming laxatives first in pregnancy.
  • Have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
  • Have kidney or liver problems.
  • Are taking diuretics (water tablets), as these may increase the risk of electrolyte imbalance when combined with stimulant laxatives.

Drug interactions to be aware of:

  • Antibiotics (e.g. neomycin) may reduce the effectiveness of sodium picosulfate by altering gut bacteria that activate the drug.
  • Diuretics and corticosteroids may increase the risk of low potassium (hypokalaemia) when used alongside stimulant laxatives.
  • Digoxin and other heart medicines — electrolyte disturbances caused by laxative overuse can affect how these medicines work.

 

How Should You Use Dulcolax Pico Liquid?

 

Always use this medicine exactly as described in the patient information leaflet or as directed by your pharmacist. The liquid should be measured carefully using the measuring device provided with the pack.

  1. Shake the bottle gently before use if instructed on the label.
  2. Measure the correct dose using the measuring cup or spoon provided.
  3. You may mix the dose with a small amount of water if preferred.
  4. Swallow the dose — do not chew or hold in the mouth.
  5. Take at bedtime to allow the laxative to work overnight.
  6. Drink plenty of fluids throughout the day (at least 6–8 glasses of water).
Age Group Dose Frequency
Adults and children aged 10+ 5ml–15ml (5mg–15mg) Once daily at bedtime
Children aged 4–10 years 2.5ml–5ml (2.5mg–5mg) Once daily at bedtime
Children under 4 years Not recommended

Do not exceed the maximum recommended dose. If constipation persists for more than 5 days, stop use and consult your doctor or pharmacist. For families managing digestive health across different age groups, our baby and toddler range includes age-appropriate options for younger children who cannot use this product.

 

What Are the Possible Side Effects of Dulcolax Pico Liquid?

 

Like all medicines, Dulcolax Pico Liquid can cause side effects, although not everyone gets them. If you experience any severe or persistent symptoms, stop use and seek medical advice.

Common side effects (may affect up to 1 in 10 people):

  • Abdominal cramps or pain
  • Diarrhoea
  • Nausea
  • Loose or watery stools

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness or light-headedness (particularly on standing)
  • Vomiting
  • Electrolyte disturbances (e.g. low potassium) — more likely with prolonged use or high doses
  • Rectal discomfort

If you notice blood in your stool, experience severe abdominal pain, or feel faint, stop taking the product immediately and contact your GP or call 111.

 

How Should You Store Dulcolax Pico Liquid?

 

Correct storage helps maintain the quality and safety of the medicine. If you're also managing other health conditions, our haemorrhoids and piles range may be relevant, as straining during constipation can worsen piles.

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and heat sources.
  • Keep the bottle tightly closed after each use.
  • Store out of the sight and reach of children.
  • Do not use after the expiry date printed on the bottle or carton.
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Dulcolax Pico Liquid online in the UK?

You can buy Dulcolax Pico Liquid Laxative 300ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter medicine. Browse our full constipation range for more options alongside this product.

How does sodium picosulfate liquid work in the body?

Sodium picosulfate is a stimulant laxative that travels to the colon, where gut bacteria convert it into an active compound called BHPM. This compound stimulates the nerve endings in the bowel wall, increasing muscular contractions and promoting a bowel movement. The effect typically occurs within 6 to 12 hours of taking the dose.

How do I use Dulcolax Pico Liquid step by step?

Measure your dose carefully using the measuring device provided, mix with a little water if you prefer, and swallow. It is best taken at bedtime so the laxative can work overnight, producing a bowel movement the following morning. Always drink plenty of fluids throughout the day when using any laxative.

What is the correct dose of Dulcolax Pico Liquid for adults?

The usual adult dose is 5ml to 15ml (equivalent to 5mg to 15mg of sodium picosulfate) taken once daily at bedtime. Always start with the lowest effective dose — 5ml — and only increase if needed. Do not exceed 15ml in any 24-hour period without medical advice.

How long does Dulcolax Pico Liquid take to work?

Dulcolax Pico Liquid typically produces a bowel movement within 6 to 12 hours of taking the dose. This is why it is usually recommended to take it at bedtime, so that the effect occurs the following morning. If you take it during the day, be aware that you may need to be near a toilet within that timeframe.

Can children use Dulcolax Pico Liquid?

Yes, Dulcolax Pico Liquid can be used in children aged 4 years and over, but the dose is lower than for adults. Children aged 4 to 10 years should take 2.5ml to 5ml once daily at bedtime. Children under 4 years should not use this product — speak to your GP or health visitor for advice on managing constipation in very young children.

What are the side effects of Dulcolax Pico Liquid?

The most common side effects include abdominal cramps, diarrhoea, and nausea, which are generally mild and short-lived. Less commonly, you may experience dizziness, vomiting, or electrolyte disturbances, particularly if you take more than the recommended dose. If you experience severe abdominal pain or blood in your stool, stop use and seek medical advice promptly.

Can I use Dulcolax Pico Liquid during pregnancy?

You should speak to your doctor or pharmacist before using Dulcolax Pico Liquid if you are pregnant. The NHS recommends bulk-forming laxatives as the first choice for constipation during pregnancy, as they are considered safer. Stimulant laxatives like sodium picosulfate are generally only used in pregnancy when other options have not worked and under medical guidance.

What happens if I miss a dose of Dulcolax Pico Liquid?

If you forget to take a dose, simply take it the next evening at bedtime as usual. Do not take a double dose to make up for a missed one. Dulcolax Pico Liquid is intended for short-term, occasional use rather than a strict daily regimen, so missing a single dose is unlikely to cause any problems.

What are the alternatives to Dulcolax Pico Liquid for constipation?

There are several types of laxatives available, including bulk-forming laxatives (such as ispaghula husk), osmotic laxatives (such as lactulose or macrogol), and stool softeners. The NHS recommends trying dietary changes — increasing fibre and fluid intake — before using any laxative. You can explore our constipation treatments range to compare available options.

How long can I use Dulcolax Pico Liquid for?

Dulcolax Pico Liquid is intended for short-term use only — generally no more than 5 consecutive days without consulting a doctor or pharmacist. Using stimulant laxatives for prolonged periods can lead to dependence, electrolyte imbalances, and reduced bowel function over time. If your constipation is persistent or recurring, speak to your GP to identify any underlying cause.

Can I take Dulcolax Pico Liquid with other medicines?

Some medicines can interact with sodium picosulfate. Antibiotics may reduce its effectiveness by altering the gut bacteria needed to activate the drug, while diuretics and corticosteroids may increase the risk of low potassium when taken alongside it. Always tell your pharmacist about all medicines you are currently taking before starting Dulcolax Pico Liquid.

Is Dulcolax Pico Liquid suitable for elderly people?

Dulcolax Pico Liquid can be used by older adults, but care should be taken as elderly people are more susceptible to dehydration and electrolyte disturbances. It is advisable to start with the lowest effective dose and ensure adequate fluid intake. If an elderly person is taking multiple medicines or has kidney or heart conditions, a pharmacist or GP should be consulted first.

What are the latest findings on sodium picosulfate for constipation?

Sodium picosulfate has been used as a stimulant laxative for several decades and remains a well-recognised option in clinical practice. Current NHS and NICE guidance supports its short-term use for occasional constipation in adults and children aged 4 and over. Research continues to support the importance of addressing underlying dietary and lifestyle factors alongside any laxative treatment for the best long-term outcomes.

Does Dulcolax Pico Liquid interact with IBS symptoms?

If you have irritable bowel syndrome (IBS), you should speak to your GP or pharmacist before using any stimulant laxative, as it may worsen cramping or unpredictable bowel habits in some people. IBS-related constipation is often better managed with specific IBS treatments rather than stimulant laxatives. Our IBS and cramps range includes products that may be more appropriate for IBS-related symptoms.

How Should You Use Dulcolax Pico Liquid?

Using Dulcolax Pico Liquid correctly makes a real difference to how well it works and how comfortable the experience is. Always read the patient information leaflet supplied with the pack before use, and follow these steps carefully.

Taking the dose at bedtime is strongly recommended so that the medicine can work while you sleep, with a bowel movement expected the following morning.

What Is the Correct Dose of Dulcolax Pico Liquid?

The dose varies depending on age. Always start with the lowest effective dose and only increase if needed. Never exceed the maximum recommended dose for your age group.

If you are unsure which dose is right for you, ask your pharmacist before starting treatment. Adjusting the dose gradually is the safest approach.

When Is the Best Time to Use Dulcolax Pico Liquid?

The best time to take Dulcolax Pico Liquid is at bedtime. Because the medicine takes 6 to 12 hours to produce a bowel movement, taking it in the evening means the effect will occur the following morning — which is far more convenient for most people. Avoid taking it in the morning or early afternoon unless you are prepared to be near a toilet during the day.

Try to take it at roughly the same time each evening if you are using it on consecutive days, and always ensure you are well hydrated before and after taking the dose.

How Long Can You Use Dulcolax Pico Liquid For?

Dulcolax Pico Liquid is designed for short-term use only. You should not use it for more than 5 consecutive days without speaking to a doctor or pharmacist. Prolonged use of stimulant laxatives can lead to the bowel becoming reliant on them to function, and may cause electrolyte imbalances over time.

If your constipation does not improve within 5 days, or if it keeps coming back, it is important to see your GP. Persistent constipation can sometimes indicate an underlying condition that needs investigation. Lifestyle changes — including increasing dietary fibre, drinking more fluids, and exercising regularly — are the most sustainable long-term approach to bowel health.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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Easycto order easy to pay good price and fast delivery thankyou

What Are the Most Common Side Effects of Dulcolax Pico Liquid?

Most people who use Dulcolax Pico Liquid at the recommended dose tolerate it well. However, as with any stimulant laxative, some side effects can occur. The most common ones are related to the medicine's action on the bowel and are usually mild and temporary.

  • Abdominal cramps or stomach pain
  • Diarrhoea or loose stools
  • Nausea
  • Urgency to use the toilet

These effects are more likely if you take a higher dose than recommended. Starting with the lowest effective dose — 5ml for adults — reduces the likelihood of experiencing them.

What Are the Less Common Side Effects of Dulcolax Pico Liquid?

Less commonly, some people may experience side effects that are not directly related to bowel activity. These are more likely with prolonged use or if the recommended dose is exceeded.

  • Dizziness or light-headedness, particularly when standing up quickly
  • Vomiting
  • Rectal discomfort or irritation
  • Electrolyte disturbances, such as low potassium (hypokalaemia) — symptoms may include muscle weakness, fatigue, or irregular heartbeat
  • Dehydration, especially if diarrhoea is prolonged

Electrolyte disturbances are more of a concern in elderly patients, those taking diuretics, or anyone using laxatives for longer than recommended.

What Are the Serious Side Effects of Dulcolax Pico Liquid?

Serious side effects from Dulcolax Pico Liquid are rare when the product is used as directed. However, you should stop taking it immediately and seek urgent medical attention if you notice any of the following:

  • Blood in your stool or rectal bleeding
  • Severe or worsening abdominal pain
  • Signs of a severe allergic reaction — including swelling of the face, lips, or throat, difficulty breathing, or a widespread skin rash
  • Fainting or collapse
  • Persistent vomiting that prevents you from keeping fluids down

These symptoms may indicate a more serious underlying condition and require prompt medical assessment.

What Should You Do If You Experience Side Effects?

If you experience mild side effects such as cramps or loose stools, these will usually resolve once the medicine has worked and you stop taking it. Staying well hydrated is important — drink plenty of water to replace any fluids lost. If side effects are troublesome or do not settle, stop use and speak to your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Dulcolax Pico Liquid Interact With Other Medicines?

Yes, certain medicines can interact with sodium picosulfate. Antibiotics such as neomycin may reduce the effectiveness of the laxative by disrupting the gut bacteria needed to activate it. Diuretics (water tablets) and corticosteroids taken alongside stimulant laxatives may increase the risk of low potassium levels. If you take digoxin or other heart medicines, electrolyte disturbances caused by laxative use could affect how those medicines work. Always inform your pharmacist of all medicines, supplements, and herbal remedies you are taking before using this product.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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