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Cyanocobalamin Vitamin B12 ,50 Tablets

Cyanocobalamin Vitamin B12 ,50 Tablets

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  • ✔️ Supports red blood cell formation and reduces fatigue from B12 deficiency
  • ✔️ Maintains healthy nerve function and neurological wellbeing
  • ✔️ Suitable for vegans, vegetarians, and older adults at risk of deficiency
  • ✔️ 50-tablet pack provides over seven weeks of daily supplementation
  • ✔️ Synthetic cyanocobalamin form offers excellent stability and shelf life

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What Are Vitamin B12 Tablets and Who Needs Them?

 

Vitamin B12 is an essential nutrient your body cannot make on its own — you have to get it from food or supplements. It plays a critical role in producing red blood cells, maintaining healthy nerve tissue, and supporting normal energy metabolism. When levels drop too low, you can feel exhausted, experience tingling in your hands and feet, or notice changes in your mood and memory. Cured Pharmacy's Cyanocobalamin vitamin B12 tablets offer a straightforward, affordable way to top up your levels without needing a prescription.

B12 deficiency is more common than many people realise. The NHS estimates it affects around 6% of adults under 60 in the UK, rising significantly in older age groups. Certain diets, medications, and health conditions can all reduce how much B12 your body absorbs. If you're looking to support your overall health alongside other supplements, you can browse our full range at Vitamins and Supplements.

 

How Do Cyanocobalamin Tablets Work in the Body?

 

Cyanocobalamin is a synthetic, stable form of vitamin B12. Once swallowed, it is absorbed in the small intestine — a process that requires a protein called intrinsic factor, produced by the stomach lining. After absorption, the body converts cyanocobalamin into its two active forms: methylcobalamin and adenosylcobalamin.

  • Methylcobalamin supports the nervous system and helps produce myelin, the protective sheath around nerve fibres.
  • Adenosylcobalamin is involved in energy production within cells, particularly in the metabolism of fatty acids and amino acids.
  • Both active forms contribute to DNA synthesis and the healthy formation of red blood cells in bone marrow.
  • Adequate B12 also helps regulate homocysteine levels, an amino acid linked to cardiovascular health when elevated.

 

Who Should Consider Taking These B12 Tablets?

 

Not everyone needs a B12 supplement, but certain groups are at a noticeably higher risk of deficiency. The NHS identifies several populations who may benefit from regular supplementation.

  • Vegans and strict vegetarians, as B12 is found almost exclusively in animal-derived foods.
  • Adults over 50, whose stomach acid production often declines, reducing B12 absorption.
  • People taking metformin for type 2 diabetes, which can interfere with B12 uptake over time.
  • Those on long-term proton pump inhibitors (PPIs) for acid reflux or stomach ulcers.
  • Individuals with conditions affecting the gut, such as Crohn's disease or coeliac disease.

If you follow a plant-based diet and are also managing other aspects of your health, it's worth knowing that our Vegan collection includes a range of products suited to your lifestyle.

 

How Do Cyanocobalamin Tablets Compare to Methylcobalamin?

 

Feature Cyanocobalamin (This Product) Methylcobalamin (Alternative)
Form Synthetic, stable Natural, active form
Conversion needed Yes — converted in the body No — already active
Shelf stability High — longer shelf life Lower — more light-sensitive
Cost Generally lower cost Typically more expensive
Suitable for vegans Yes Yes

 

Is Cyanocobalamin Safe to Store at Home?

 

Yes. Vitamin B12 tablets in cyanocobalamin form are particularly stable, making them easy to store at home without special equipment. Keep them in a cool, dry place below 25°C, away from direct sunlight and moisture. Always store medicines out of the reach and sight of children. Do not use after the expiry date printed on the packaging.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Cyanocobalamin Vitamin B12 50 Tablets specifications
Treatment category Vitamin and mineral supplement
Mechanism of action Replenishes vitamin B12; supports red blood cell formation, nerve function, and DNA synthesis
Effective for Dietary vitamin B12 supplementation; supporting energy metabolism
Suitable for Adults; vegans; vegetarians; older adults; those on certain medications
Active ingredient Cyanocobalamin (Vitamin B12)
Pack size 50 tablets
UK classification General Sale List (GSL)
Drug class Water-soluble vitamin
Preparation Tablet
Route of administration Oral

Specifications of Cyanocobalamin Vitamin B12 50 Tablets

 

What Is Cyanocobalamin Vitamin B12 and What Is It Used For?

 

Cyanocobalamin Vitamin B12 50 Tablets are an oral dietary supplement used to maintain adequate vitamin B12 levels in the body. Vitamin B12 is essential for the normal functioning of the brain and nervous system, the formation of red blood cells, and the synthesis of DNA. A deficiency can lead to megaloblastic anaemia, fatigue, neurological symptoms such as tingling or numbness, and mood disturbances. These tablets are intended for adults who need to supplement their dietary intake of B12 — particularly those following plant-based diets or those whose absorption may be compromised.

 

What Do You Need to Know Before Using These Tablets?

 

Before taking cyanocobalamin tablets, it is important to consider whether they are appropriate for you. Read the following carefully.

Do not take these tablets if you:

  • Are allergic to cyanocobalamin, cobalt, or any other ingredient in the product.
  • Have Leber's hereditary optic neuropathy — cyanocobalamin is contraindicated in this condition.
  • Are a child under 18 unless directed by a healthcare professional.

Speak to your doctor or pharmacist before taking if you:

  • Are pregnant or breastfeeding — B12 requirements increase during pregnancy.
  • Have pernicious anaemia — oral supplementation alone may not be sufficient; injections may be required.
  • Have any kidney or liver conditions.
  • Are being treated for polycythaemia vera.

Medicines that may interact with cyanocobalamin:

  • Metformin — long-term use can reduce B12 absorption.
  • Proton pump inhibitors (e.g. omeprazole) and H2 blockers — reduce stomach acid needed for B12 release from food.
  • Chloramphenicol — may reduce the response to B12 supplementation.
  • Colchicine and neomycin — may impair B12 absorption.

 

How Should You Use Cyanocobalamin Vitamin B12 Tablets?

 

Always use this product as directed on the label or as advised by your pharmacist. Do not exceed the stated dose.

  1. Take one tablet daily with a glass of water.
  2. Swallow the tablet whole — do not crush or chew unless the product is specifically formulated for that.
  3. You can take it with or without food, though taking it with a meal may help reduce any mild stomach discomfort.
  4. Try to take it at the same time each day to maintain consistent levels.
  5. If you miss a dose, take it as soon as you remember — unless it is nearly time for your next dose. Never double up.
Indication Age Group Dose Frequency
Dietary supplementation Adults 18+ 1 tablet Once daily
Vegan/vegetarian diet support Adults 18+ 1 tablet Once daily
Not recommended Under 18 Seek medical advice

If you are managing a long-term condition such as diabetes and are concerned about nutrient levels, our Diabetes Monitoring collection may also be of interest.

 

What Are the Possible Side Effects of Cyanocobalamin Tablets?

 

Cyanocobalamin is generally very well tolerated. Serious side effects are rare, but you should be aware of what to look out for.

Common side effects (may affect up to 1 in 10 people):

  • Nausea or mild stomach upset
  • Diarrhoea
  • Headache

Less common side effects (may affect up to 1 in 100 people):

  • Skin reactions such as itching or rash
  • Dizziness
  • Flushing of the skin
  • Swelling of the face, lips, or throat (seek immediate medical help if this occurs — this may indicate an allergic reaction)

If you experience any side effect that concerns you, stop taking the tablets and speak to your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

 

How Should You Store Cyanocobalamin Vitamin B12 Tablets?

 

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and moisture.
  • Store out of the reach and sight of children.
  • Do not use after the expiry date printed on the packaging.
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy.

If you are looking for other health essentials to support your wellbeing, explore our Women's Health collection for a range of products tailored to specific needs.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy vitamin B12 tablets online in the UK?

You can buy Cyanocobalamin Vitamin B12 50 Tablets directly from Cured Pharmacy online for just £5.80. No prescription is needed as these are a General Sale List (GSL) medicine. They are dispatched quickly and conveniently to your home address. You can also browse our full Vitamins and Supplements range for related products.

How does cyanocobalamin work in the body?

Once absorbed in the small intestine, cyanocobalamin is converted into two active forms — methylcobalamin and adenosylcobalamin. These support red blood cell production, DNA synthesis, and the maintenance of healthy nerve tissue. The conversion process requires adequate stomach acid and a protein called intrinsic factor. Without sufficient B12, red blood cells can become abnormally large and function poorly.

How do I take cyanocobalamin vitamin B12 tablets correctly?

Take one tablet daily with a full glass of water, with or without food. Swallow the tablet whole and try to take it at the same time each day to keep your levels consistent. Do not take more than the recommended dose unless advised by a healthcare professional.

What is the best time of day to take vitamin B12 tablets?

There is no strict rule, but many people prefer to take B12 in the morning as it is involved in energy metabolism and may feel more natural alongside breakfast. Consistency matters more than timing — pick a time that fits your routine and stick to it. Taking it with food can also help minimise any mild stomach discomfort.

What are the side effects of cyanocobalamin tablets and how do I manage them?

Most people tolerate cyanocobalamin very well. Mild side effects such as nausea, headache, or loose stools can occasionally occur, particularly when first starting supplementation. Taking the tablet with food usually helps. If you develop a skin rash, swelling, or difficulty breathing, stop taking the tablets immediately and seek medical advice.

Who is eligible to take cyanocobalamin vitamin B12 tablets?

These tablets are suitable for adults aged 18 and over who need to supplement their dietary B12 intake. They are particularly useful for vegans, vegetarians, older adults, and people taking medicines such as metformin or proton pump inhibitors. They are not recommended for children under 18 without medical supervision, and people with Leber's hereditary optic neuropathy should not take cyanocobalamin.

What happens if I miss a dose of vitamin B12 tablets?

If you forget to take your tablet, take it as soon as you remember — unless it is nearly time for your next scheduled dose. In that case, simply skip the missed dose and continue as normal. Never take two tablets at once to compensate for a missed one, as this is unnecessary and could cause mild side effects.

Are cyanocobalamin B12 tablets suitable for vegans?

Yes. Cyanocobalamin is a synthetically produced form of vitamin B12 and does not involve animal-derived ingredients in its manufacture, making it suitable for vegans. The NHS specifically recommends that people following a vegan diet supplement with B12, as it is not naturally present in plant foods. You can find more vegan-friendly health products in our Vegan collection.

How long does it take for vitamin B12 tablets to work?

Some people notice improvements in energy levels and mood within two to four weeks of consistent daily supplementation. However, if you have a significant deficiency, it may take several months of regular use before your B12 levels fully normalise. A blood test from your GP is the most reliable way to monitor your progress.

How long can you take vitamin B12 tablets for?

For people with ongoing dietary restrictions or absorption issues, long-term daily supplementation is generally considered safe. B12 is a water-soluble vitamin, meaning excess amounts are excreted in urine rather than accumulating to toxic levels. That said, if you are taking B12 for a diagnosed deficiency, your GP may want to monitor your levels periodically.

Can I take vitamin B12 tablets with other medicines?

Cyanocobalamin can interact with certain medicines, including metformin, proton pump inhibitors, chloramphenicol, and colchicine. These medicines may reduce the absorption or effectiveness of B12 supplementation. Always inform your pharmacist or GP about all medicines and supplements you are taking before starting cyanocobalamin.

What are the alternatives to cyanocobalamin vitamin B12 tablets?

The main alternatives include methylcobalamin and hydroxocobalamin. Methylcobalamin is the active form of B12 and does not require conversion in the body. Hydroxocobalamin is typically given by injection and is the preferred form for treating pernicious anaemia or severe deficiency under NHS guidelines. For mild dietary supplementation, cyanocobalamin tablets are a practical and cost-effective option.

Can vitamin B12 tablets help with tiredness and fatigue?

If your fatigue is caused by low B12 levels, supplementation can help restore energy over time. B12 plays a direct role in energy metabolism and red blood cell production, both of which affect how energised you feel day to day. However, tiredness has many causes — if symptoms persist, speak to your GP to rule out other conditions.

Is it safe to take vitamin B12 tablets during pregnancy?

Vitamin B12 requirements increase during pregnancy, and deficiency can affect both mother and baby. However, you should always speak to your GP or midwife before starting any new supplement during pregnancy. They can advise on the appropriate dose and whether a combined prenatal supplement might be more suitable for your needs.

What does the latest research say about vitamin B12 supplementation?

Current evidence supports oral cyanocobalamin supplementation as an effective approach for correcting mild to moderate B12 deficiency in people who can absorb it normally. Research also highlights the importance of B12 in reducing elevated homocysteine levels, which are associated with cardiovascular and neurological risk. The NHS and BNF continue to recommend B12 supplementation for at-risk groups including vegans and older adults.

How Should You Use Cyanocobalamin Vitamin B12 Tablets?

Using these tablets correctly is straightforward, but a few simple steps will help you get the most from them. Always read the product label before starting and follow the instructions provided. If you have any questions, your pharmacist is always a good first point of contact.

What Is the Correct Dose of Cyanocobalamin Vitamin B12 Tablets?

The standard dose for adults using these tablets as a dietary supplement is one tablet per day. Do not exceed this dose unless specifically directed by a healthcare professional. The table below summarises dosing guidance by indication and age group.

When Is the Best Time to Use Cyanocobalamin Vitamin B12 Tablets?

There is no clinically mandated time of day for taking B12 tablets, but many people find mornings work well since B12 supports energy metabolism and taking it early feels intuitive alongside breakfast. What matters most is consistency — taking your tablet at the same time every day helps maintain steady levels and makes it easier to remember. If you find morning doses difficult to remember, linking the habit to another daily routine, such as brushing your teeth, can help.

How Long Can You Use Cyanocobalamin Vitamin B12 Tablets For?

For people with ongoing dietary restrictions — such as vegans or vegetarians — or those with conditions that impair B12 absorption, long-term daily supplementation is generally considered safe. Because B12 is water-soluble, excess amounts are excreted by the kidneys rather than stored to harmful levels. If you are supplementing to address a diagnosed deficiency, your GP may recommend periodic blood tests to monitor your levels and adjust your approach accordingly. Always seek medical advice if your symptoms do not improve after several weeks of supplementation.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Cyanocobalamin Vitamin B12 Tablets?

Cyanocobalamin is one of the most well-tolerated supplements available. The vast majority of people who take it experience no side effects at all. That said, a small number of users may notice mild gastrointestinal symptoms, particularly when first starting supplementation.

  • Nausea or mild stomach upset
  • Diarrhoea or loose stools
  • Headache
  • Loss of appetite

These effects are usually temporary and often resolve on their own within a few days. Taking the tablet with food can help reduce stomach-related discomfort.

What Are the Less Common Side Effects of Cyanocobalamin Tablets?

Less commonly, some people may experience skin or systemic reactions. These are not typical but are worth being aware of before you start taking the supplement.

  • Skin itching or rash
  • Flushing or redness of the skin
  • Dizziness
  • Swelling of the ankles or feet
  • Acne-like skin eruptions (particularly with high-dose supplementation)

What Are the Serious Side Effects of Cyanocobalamin Tablets?

Serious side effects are rare but can occur. An allergic reaction to cyanocobalamin, though uncommon, requires immediate medical attention. Signs of a serious allergic reaction include swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, a sudden drop in blood pressure, or a widespread skin rash. If you experience any of these symptoms, stop taking the tablets immediately and call 999 or go to your nearest A&E department.

What Should You Do If You Experience Side Effects?

For mild side effects such as nausea or headache, try taking the tablet with food and ensure you are drinking enough water throughout the day. If symptoms persist beyond a few days or become bothersome, speak to your pharmacist — they can advise whether you should continue or switch to an alternative form of B12. You can also report any suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in the UK.

Can Cyanocobalamin Interact With Other Medicines?

Yes, certain medicines can affect how well cyanocobalamin is absorbed or how effectively it works in the body. The most clinically significant interactions include metformin (used for type 2 diabetes), proton pump inhibitors such as omeprazole, H2 receptor antagonists, chloramphenicol (an antibiotic), and colchicine (used for gout). If you are taking any of these medicines, speak to your GP or pharmacist before starting cyanocobalamin supplementation. They can advise on timing, dose adjustments, or whether additional monitoring of your B12 levels is appropriate.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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