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Care Glycerin Adult 4g - 12 Suppositories - Brand May Vary

Care Glycerin Adult 4g - 12 Suppositories - Brand May Vary

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  • ✔️ Relieves occasional constipation within 15 to 30 minutes
  • ✔️ Acts locally in the rectum with minimal systemic absorption
  • ✔️ Each pack contains 12 adult-strength 4g suppositories
  • ✔️ Suitable for adults needing fast-acting rectal laxative relief
  • ✔️ Generally considered safe in pregnancy with professional guidance

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What Are Glycerin Suppositories and How Do They Help?

 

Constipation is something most people experience at some point — and it can be genuinely uncomfortable. Glycerin suppositories are a well-established, over-the-counter rectal laxative used to relieve occasional constipation in adults. Each suppository in this pack contains 4g of glycerol (glycerin) as the active ingredient, and the pack contains 12 suppositories, giving you a reliable supply at an accessible price of just £3.12. The brand may vary, but the formulation and strength remain consistent.

Glycerol has been used as a rectal laxative for decades. It is listed in the British National Formulary (BNF) as a stimulant laxative suitable for short-term use. If you are also managing other digestive concerns, you might find our constipation collection helpful for exploring additional options.

 

How Do Glycerin Suppositories Work in the Body?

 

Understanding the mechanism helps you use this product with confidence. Glycerol works through two complementary actions once inserted rectally:

  • Osmotic effect: Glycerol draws water into the rectum from surrounding tissues, softening the stool and making it easier to pass.
  • Local irritant effect: It mildly stimulates the rectal mucosa, triggering peristaltic contractions — the wave-like muscle movements that push stool towards the anus.
  • Lubrication: The suppository itself provides a degree of lubrication as it melts, easing the passage of hard stools.
  • Rapid onset: Most people experience a bowel movement within 15 to 30 minutes of insertion.

Because the action is local rather than systemic, glycerol is not absorbed into the bloodstream in meaningful amounts, which is one reason it is considered suitable for a range of patients.

 

Who Is This Product Suitable For?

 

This product is designed for adults experiencing occasional constipation. It is particularly useful when you need relatively quick relief — for example, before a medical procedure, or when oral laxatives have not worked quickly enough. It may also be appropriate for people who have difficulty swallowing tablets.

  • Adults aged 18 and over with occasional constipation
  • People who prefer a locally acting, non-systemic laxative
  • Those who need faster relief than oral laxatives typically provide
  • Patients advised by a healthcare professional to use a rectal laxative

It is not suitable for children under 12 without medical supervision. Always read the label carefully before use.

 

How Do Glycerin Suppositories Compare to Other Laxatives?

 

Feature Glycerin Suppositories 4g Oral Osmotic Laxative (e.g. Lactulose)
Route of administration Rectal Oral
Onset of action 15–30 minutes 24–48 hours
Systemic absorption Minimal Moderate
Suitable for pregnancy (with advice) Generally yes Generally yes

 

Are Glycerin Suppositories Safe to Store at Home?

 

Yes — storage is straightforward. Keep the suppositories below 25°C in a cool, dry place away from direct sunlight. Do not refrigerate unless the packaging specifically instructs you to, as very cold temperatures can make insertion uncomfortable. Keep them out of reach of children at all times.

If you are managing multiple health conditions alongside constipation — such as haemorrhoids, which can make bowel movements more painful — it is worth browsing our haemorrhoids and piles collection for complementary products that may help.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Care Glycerin Adult 4g - 12 Suppositories specifications
Treatment category Constipation / Laxative
Mechanism of action Osmotic and local stimulant laxative
Effective Within 15–30 minutes
Suitable for Adults aged 18 and over
Active ingredient Glycerol (Glycerin) 4g
Pack sizes 12 suppositories
Strengths 4g per suppository
UK classification General Sale / Pharmacy Medicine (P)
Drug class Stimulant / osmotic laxative
Preparation Suppository
Route of administration Rectal

Specifications of Care Glycerin Adult 4g - 12 Suppositories

 

What Are Glycerin Suppositories Used For?

 

Glycerin suppositories 4g are used for the short-term relief of occasional constipation in adults. Constipation is defined by the NHS as passing fewer than three stools per week, or passing stools that are hard, dry, and difficult to pass. This product acts locally in the rectum to soften stool and stimulate a bowel movement, usually within 15 to 30 minutes. It is not intended to treat the underlying cause of constipation — lifestyle changes such as increased fibre intake, hydration, and physical activity remain important alongside any laxative use.

 

What Do You Need to Know Before Using Glycerin Suppositories?

 

Before using this product, read the following carefully. Do not use glycerin suppositories if any of the following apply to you:

  • You are allergic to glycerol or any other ingredient in the suppository
  • You have an acute inflammatory bowel condition such as Crohn's disease or ulcerative colitis (during a flare)
  • You have rectal bleeding of unknown cause
  • You have recently had rectal or bowel surgery
  • You have a bowel obstruction or suspected obstruction
  • You are under 12 years of age (use the paediatric formulation instead)

Speak to your GP or pharmacist before use if you are pregnant, breastfeeding, or have haemorrhoids that are actively bleeding. Glycerin suppositories are generally considered low-risk in pregnancy, but professional guidance is always advisable.

Drug interactions: No significant drug interactions are known for rectally administered glycerol. However, always inform your pharmacist of all medicines you are taking.

  • No clinically significant interactions with oral medicines have been identified
  • Avoid concurrent use of other rectal preparations unless advised by a healthcare professional

 

How Should You Use Glycerin Suppositories Correctly?

 

Follow these steps carefully to ensure safe and effective use. If you are unsure at any point, ask your pharmacist for guidance.

  1. Wash your hands thoroughly with soap and water before and after use.
  2. Remove the suppository from its foil or plastic packaging.
  3. Lie on your left side with your knees drawn up towards your chest (the left lateral position).
  4. Gently insert the suppository pointed end first into the rectum, pushing it in approximately 2–3 cm.
  5. Remain lying down for at least 15 minutes to allow the suppository to dissolve and take effect.
  6. Try to resist the urge to open your bowels for as long as comfortable — this helps the suppository work fully.
Indication Age Group Dose Frequency
Occasional constipation Adults (18+) One 4g suppository Once daily as needed
Occasional constipation Children (under 12) Use paediatric formulation only As directed by a doctor

Do not use more than one adult suppository per day unless specifically advised by a healthcare professional. If constipation persists for more than five days, stop use and consult your GP.

 

What Are the Possible Side Effects of Glycerin Suppositories?

 

Like all medicines, glycerin suppositories can cause side effects, although not everyone experiences them. Most side effects are mild and short-lived.

Common side effects:

  • Mild rectal irritation or a burning sensation
  • A feeling of urgency to open your bowels
  • Mild abdominal cramping or discomfort

Less common side effects:

  • Rectal discomfort lasting beyond the bowel movement
  • Diarrhoea if the suppository acts more strongly than expected
  • Rarely, localised allergic reaction (redness, swelling, or itching around the rectum)

If you experience severe pain, rectal bleeding, or signs of an allergic reaction, stop use immediately and seek medical advice. You may also find it useful to explore our IBS and cramps collection if abdominal discomfort is a recurring issue for you.

 

How Should You Store Glycerin Suppositories?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Do not freeze or refrigerate unless the packaging states otherwise
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the packaging
  • Do not dispose of medicines via wastewater or household waste — return unused suppositories to your pharmacy

For other digestive health products and related remedies, take a look at our diarrhoea collection for complementary support options.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy glycerin suppositories online in the UK?

You can buy glycerin suppositories online in the UK directly from Cured Pharmacy for just £3.12 per pack of 12. No prescription is required, as they are available over the counter. Simply add to your basket and choose your preferred delivery option at checkout.

How do glycerin suppositories work in the body?

Glycerin suppositories work by drawing water into the rectum through osmosis, which softens the stool and makes it easier to pass. They also mildly stimulate the rectal lining, triggering the muscle contractions needed for a bowel movement. Most people experience relief within 15 to 30 minutes of insertion.

How do I insert a glycerin suppository step by step?

Wash your hands, then lie on your left side with your knees bent towards your chest. Remove the suppository from its packaging and gently insert it pointed end first into the rectum, pushing it in about 2–3 cm. Stay lying down for at least 15 minutes to allow it to dissolve and take effect.

How long do glycerin suppositories take to work?

Glycerin suppositories typically produce a bowel movement within 15 to 30 minutes of insertion. If no result occurs within an hour, do not insert another suppository — instead, contact your pharmacist for advice. They are one of the faster-acting options available without a prescription.

Are glycerin suppositories safe to use during pregnancy?

Glycerin suppositories are generally considered one of the safer laxative options during pregnancy because they act locally in the rectum with minimal systemic absorption. However, you should always speak to your midwife, GP, or pharmacist before using any medicine while pregnant. Do not self-treat constipation in pregnancy without professional guidance.

What is the correct dose of glycerin suppositories for adults?

The standard adult dose is one 4g suppository, used once daily as needed. Do not use more than one per day unless a healthcare professional has specifically advised you to do so. If constipation persists beyond five days, stop use and consult your GP.

What are the side effects of glycerin suppositories?

The most common side effects include mild rectal irritation, a sensation of urgency, and mild abdominal cramping — all of which are usually brief and resolve after the bowel has emptied. Less commonly, you may experience localised discomfort or, rarely, a mild allergic reaction around the rectum. If you notice rectal bleeding or severe pain, stop use and seek medical advice promptly.

Can I use glycerin suppositories every day?

Glycerin suppositories are intended for occasional, short-term use only — not as a daily long-term solution. Using them regularly without medical advice may mask an underlying condition that needs investigation. If you find yourself needing a laxative frequently, speak to your GP about the cause of your constipation.

Who should not use glycerin suppositories?

You should not use this product if you have a known allergy to glycerol, a bowel obstruction, active rectal bleeding of unknown cause, or an acute inflammatory bowel condition. Children under 12 should use a paediatric formulation rather than the adult 4g strength. Always check with your pharmacist if you are unsure whether this product is right for you.

What is the difference between glycerin suppositories and oral laxatives?

Glycerin suppositories act locally in the rectum and typically work within 15 to 30 minutes, making them faster than most oral laxatives. Oral laxatives such as lactulose or senna act throughout the digestive system and can take 24 to 48 hours to produce a result. The right choice depends on your situation — your pharmacist can help you decide. You can also browse our constipation collection for a range of options.

Can glycerin suppositories be used for haemorrhoids?

Glycerin suppositories are not specifically indicated for treating haemorrhoids, but they can help relieve constipation that makes haemorrhoids worse by reducing straining during bowel movements. If you have actively bleeding haemorrhoids, speak to your GP before using any rectal preparation. For dedicated haemorrhoid treatments, visit our haemorrhoids and piles collection.

How long can you use glycerin suppositories for?

Glycerin suppositories should only be used for short periods — generally no more than five consecutive days without medical advice. Prolonged use without identifying the underlying cause of constipation is not recommended. If your symptoms do not improve, consult your GP who can investigate further and recommend appropriate treatment.

What happens if a glycerin suppository does not work?

If you do not experience a bowel movement within an hour of inserting the suppository, do not use a second one — contact your pharmacist or GP for advice instead. Persistent constipation that does not respond to laxatives may indicate an underlying condition requiring investigation. Your doctor can assess whether further treatment or tests are needed.

Are there any alternatives to glycerin suppositories for constipation?

Yes — alternatives include oral osmotic laxatives (such as lactulose or macrogol), bulk-forming laxatives (such as ispaghula husk), and stimulant laxatives (such as senna or bisacodyl). The NHS recommends trying dietary and lifestyle changes first, including increasing fibre and fluid intake. Browse our constipation collection to compare available options.

What is the latest guidance on using glycerin suppositories?

Current NHS and BNF guidance supports the use of glycerol suppositories as a short-term rectal laxative for adults with occasional constipation. They remain a recommended option when rapid relief is needed or when oral laxatives are unsuitable. Always follow the product instructions and seek professional advice if constipation is persistent or accompanied by other symptoms such as blood in the stool or unexplained weight loss.

How Should You Use Glycerin Suppositories?

Using a glycerin suppository correctly makes a real difference to how well it works. Before you begin, make sure you have washed your hands thoroughly. The process is straightforward, and most people find it comfortable once they know what to expect.

What Is the Correct Dose of Glycerin Suppositories?

The standard adult dose is one 4g suppository, used once daily as needed. Do not use more than one suppository per day unless a healthcare professional has specifically advised otherwise. Children under 12 should use a paediatric formulation — not this adult strength product.

When Is the Best Time to Use Glycerin Suppositories?

There is no single "best" time of day, but many people find it most convenient to use a suppository in the morning after breakfast, when the body's natural urge to open the bowels is often strongest. Using it at a time when you can remain lying down for 15 to 30 minutes — and then have easy access to a toilet — makes the experience more comfortable and effective.

Avoid using the suppository immediately before going out or travelling, as the onset of action is typically within 15 to 30 minutes.

How Long Can You Use Glycerin Suppositories For?

Glycerin suppositories are intended for short-term, occasional use only. You should not use them for more than five consecutive days without seeking medical advice. If constipation persists beyond this point, or if you find yourself relying on laxatives regularly, speak to your GP — there may be an underlying cause that needs to be addressed.

Long-term laxative use without medical supervision is not recommended, as it can sometimes mask more serious conditions. Lifestyle changes such as increasing dietary fibre, drinking more water, and taking regular exercise are the foundation of managing constipation in the longer term.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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I am fully satisfied with Care Glycerin Adult 4 Suppositories

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Wyn Owen

Great service - prompt delivery and great customer support.

What Are the Most Common Side Effects of Glycerin Suppositories?

Most people tolerate glycerin suppositories well, and side effects are generally mild and short-lived. Because the product acts locally in the rectum rather than being absorbed into the bloodstream, systemic side effects are uncommon.

  • Mild rectal irritation or a warm, burning sensation after insertion
  • A strong or urgent feeling to open your bowels
  • Mild abdominal cramping or a feeling of pressure in the lower abdomen

What Are the Less Common Side Effects of Glycerin Suppositories?

Less frequently, some people may experience side effects that are slightly more noticeable, though still not usually serious. If any of the following persist or cause significant discomfort, contact your pharmacist.

  • Rectal discomfort or soreness lasting beyond the bowel movement
  • Loose stools or diarrhoea if the suppository acts more strongly than expected
  • Localised redness, itching, or swelling around the rectum — which may suggest a mild sensitivity to glycerol

What Are the Serious Side Effects of Glycerin Suppositories?

Serious side effects are rare with glycerin suppositories used as directed. However, you should stop using this product immediately and seek urgent medical attention if you experience any of the following:

  • Rectal bleeding that is not clearly related to a known condition such as haemorrhoids
  • Severe abdominal pain or cramping
  • Signs of a systemic allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash
  • No bowel movement after repeated use, which may suggest a bowel obstruction

What Should You Do If You Experience Side Effects?

For mild side effects such as rectal irritation or cramping, no specific treatment is usually needed — they typically resolve once the bowel has emptied. Staying hydrated and avoiding straining can help reduce discomfort. If side effects are persistent, worsening, or causing you concern, stop use and speak to your pharmacist or GP as soon as possible. You can report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Glycerin Suppositories Interact With Other Medicines?

No clinically significant drug interactions have been identified for rectally administered glycerol. Because the active ingredient is not meaningfully absorbed into the bloodstream, interactions with oral medicines are not expected. That said, you should always tell your pharmacist about all medicines you are currently taking — including over-the-counter products, herbal remedies, and supplements — before starting any new treatment. Avoid using other rectal preparations at the same time unless a healthcare professional has advised you to do so.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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