Skip to product information
1 of 4

  • Images are for illustration purposes only

Biofreeze Pain Relieving Gel

Biofreeze Pain Relieving Gel

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Temporarily relieves minor muscle and joint pain topically
  • ✔️ Cooling menthol sensation targets pain at the source
  • ✔️ Suitable for backache, arthritis, strains and sprains
  • ✔️ No prescription required — available over the counter
  • ✔️ Non-oral option ideal for NSAID-sensitive individuals

Price Checker

Regular price £7.49
Sale price £7.49
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Is Biofreeze Pain Relieving Gel?

 

Living with muscle aches or joint discomfort can make even the simplest daily tasks feel like a challenge. Biofreeze pain relieving gel is a topical menthol-based gel designed to provide temporary relief from minor aches and pains — without the need for a prescription. Whether you're dealing with a stiff back after a long day at your desk, post-exercise soreness, or the nagging discomfort of arthritis, this gel offers a cooling sensation that many people find genuinely soothing. You can explore a wider range of options in our pain relief collection if you're looking for alternatives alongside this product.

Biofreeze has been used by physiotherapists and sports professionals for many years, and it remains one of the most recognised topical analgesic brands available over the counter in the UK. The active ingredient is menthol at 3.5%, which works on the skin's sensory receptors to temporarily reduce the perception of pain. It's a straightforward, non-oral option — no tablets, no waiting for something to be absorbed systemically.

 

How Does Biofreeze Pain Relieving Gel Work?

 

The mechanism behind Biofreeze is known as counter-irritation, sometimes referred to as the gate control theory of pain. Essentially, the menthol in the gel stimulates cold-sensitive thermoreceptors (specifically TRPM8 receptors) in the skin. This creates a cooling sensation that competes with — and temporarily overrides — the pain signals travelling to your brain. It doesn't treat the underlying cause of pain, but it can make it significantly more manageable in the short term.

  • Menthol activates TRPM8 cold receptors in the skin
  • Cold sensation competes with pain signals via the gate control mechanism
  • Pain perception is temporarily reduced at the site of application
  • Effect is localised — no systemic absorption at standard topical doses

 

Who Should Use Biofreeze Pain Relieving Gel?

 

Biofreeze is suitable for adults and children aged 12 and over who are experiencing minor, localised musculoskeletal pain. It's particularly useful if you prefer to avoid oral pain relief, or if you need targeted relief in a specific area. That said, it's not appropriate for everyone — always check the label and speak to a pharmacist if you're unsure.

  • Adults with minor backache, muscle soreness, or joint stiffness
  • People with arthritis seeking localised, non-oral pain relief
  • Those who cannot tolerate oral NSAIDs due to stomach sensitivity
  • Active individuals managing post-exercise muscle discomfort

 

How Does Biofreeze Compare to Other Topical Pain Relief Gels?

 

Feature Biofreeze Pain Relieving Gel Ibuprofen Gel (e.g. Voltarol)
Active ingredient Menthol 3.5% Ibuprofen 5% or Diclofenac 1%
Mechanism Counter-irritation (cooling) Anti-inflammatory (NSAID)
Suitable for NSAID-sensitive users Yes No
Prescription required No No (OTC strengths)

 

Is Biofreeze Pain Relieving Gel Suitable for Sensitive Skin?

 

If you have sensitive skin, it's worth doing a small patch test before applying Biofreeze pain relieving gel to a larger area. Apply a small amount to the inside of your wrist and wait 24 hours to check for any reaction. The gel contains menthol and other excipients that may occasionally cause mild irritation in people with very reactive skin. You can also browse our creams and ointments collection for alternative topical products that may be better suited to sensitive skin types.

Do not apply Biofreeze to broken, damaged, or inflamed skin. Avoid contact with the eyes, mouth, and mucous membranes. Keep the product away from children under 12 years of age. If you experience a rash, blistering, or significant irritation, discontinue use immediately and seek advice from a pharmacist or GP.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Biofreeze Pain Relieving Gel specifications
Treatment category Topical analgesic / pain relief
Active ingredient Menthol 3.5%
Mechanism of action Counter-irritation via TRPM8 cold receptor activation
Suitable for Adults and children aged 12 and over
UK classification General Sale List (GSL)
Drug class Topical analgesic (counter-irritant)
Preparation Gel
Route of administration Topical (cutaneous)
Effective for Minor muscle aches, joint pain, backache, arthritis discomfort

Specifications of Biofreeze Pain Relieving Gel

 

What Is Biofreeze Pain Relieving Gel and What Is It Used For?

 

Biofreeze Pain Relieving Gel is an over-the-counter topical analgesic containing menthol 3.5% as its active ingredient. It is used for the temporary relief of minor aches and pains in muscles and joints. Common conditions it is used for include backache, arthritis, strains, sprains, and general muscle soreness. It works locally at the site of application and does not require oral ingestion, making it a convenient option for targeted pain management.

 

What Do You Need to Know Before Using Biofreeze Pain Relieving Gel?

 

Before using this gel, it's important to be aware of certain contraindications and precautions. Not everyone is suitable for topical menthol products, and using them incorrectly can cause harm.

Do not use Biofreeze if you:

  • Are allergic to menthol or any other ingredient in the product
  • Have broken, damaged, or infected skin at the intended application site
  • Are under 12 years of age
  • Have a known hypersensitivity to cooling agents or topical analgesics

Use with caution if you:

  • Are pregnant or breastfeeding — consult your GP or pharmacist first
  • Have eczema, psoriasis, or other chronic skin conditions
  • Are applying near the face — keep well away from eyes and nostrils
  • Are using occlusive dressings over the application site

Drug interactions:

  • No significant drug interactions are currently known for topical menthol at this concentration
  • Avoid using alongside other topical products on the same area without pharmacist advice

 

How Should You Use Biofreeze Pain Relieving Gel?

 

Using Biofreeze correctly ensures you get the most benefit while minimising any risk of skin irritation. Always read the full product label before first use. If you're managing a longer-term condition such as arthritis, it may also be worth speaking to your GP about a broader pain management plan.

  1. Wash and dry the affected area before application
  2. Squeeze a small amount of gel onto your fingertips
  3. Apply gently to the painful area using circular motions
  4. Allow the gel to absorb — do not cover with a tight bandage immediately
  5. Wash your hands thoroughly after application
  6. Avoid touching your eyes, mouth, or nose after use
Indication Age Group Dose Frequency
Muscle and joint pain Adults and children 12+ Small amount applied to affected area Up to 3–4 times daily
Backache Adults Small amount applied to lower back Up to 3–4 times daily
Arthritis discomfort Adults Small amount to affected joint Up to 3–4 times daily

 

What Are the Possible Side Effects of Biofreeze Pain Relieving Gel?

 

Side effects with topical menthol products are generally mild and uncommon. Most people tolerate Biofreeze well. However, as with any topical product, reactions can occur — particularly in those with sensitive skin. If you experience anything unexpected, stop using the gel and speak to a pharmacist. You might also find it helpful to browse our first aid collection for products to help manage minor skin reactions.

Common side effects:

  • Mild cooling or tingling sensation at the application site (this is expected)
  • Temporary redness of the skin
  • Mild skin irritation

Less common side effects:

  • Burning sensation that persists beyond the initial application
  • Skin rash or hives
  • Blistering or peeling of the skin (discontinue immediately)
  • Allergic contact dermatitis

If you experience difficulty breathing, swelling of the face or throat, or any sign of a severe allergic reaction, seek emergency medical attention immediately.

 

How Should You Store Biofreeze Pain Relieving Gel?

 

Correct storage helps maintain the product's effectiveness and safety throughout its shelf life.

  • Store below 25°C in a cool, dry place
  • Keep out of direct sunlight and away from heat sources
  • Keep the cap tightly closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not freeze the product
  • Do not store in the bathroom or near a sink where moisture may affect the product

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Biofreeze Pain Relieving Gel online in the UK?

You can buy Biofreeze Pain Relieving Gel directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as a General Sale List (GSL) medicine. Browse our full pain relief collection for more topical and oral pain relief options.

How does Biofreeze Pain Relieving Gel work in the body?

Biofreeze works through a process called counter-irritation. The menthol (3.5%) activates cold-sensitive TRPM8 receptors in the skin, producing a cooling sensation that temporarily competes with and overrides pain signals travelling to the brain. It does not treat the underlying cause of pain but provides meaningful short-term relief at the site of application.

How do I apply Biofreeze Pain Relieving Gel step by step?

Clean and dry the affected area first, then apply a small amount of gel using your fingertips in gentle circular motions. Allow it to absorb naturally — do not immediately cover with a tight bandage — and wash your hands thoroughly after application. Avoid contact with your eyes, mouth, and nostrils at all times.

How often can I use Biofreeze Pain Relieving Gel each day?

Biofreeze can be applied up to three to four times daily to the affected area. Always follow the instructions on the product label and do not exceed the recommended frequency of use. If your pain persists beyond seven days, consult your GP or pharmacist for further assessment.

What are the side effects of Biofreeze Pain Relieving Gel?

Most people tolerate Biofreeze well, but some may experience mild skin irritation, temporary redness, or a tingling sensation at the application site. Less commonly, a persistent burning sensation or skin rash may occur — if this happens, stop use immediately. Seek urgent medical attention if you notice any signs of a severe allergic reaction such as swelling or difficulty breathing.

Is Biofreeze Pain Relieving Gel safe to use during pregnancy?

If you are pregnant or breastfeeding, you should consult your GP or pharmacist before using Biofreeze. Topical menthol products are generally used with caution during pregnancy, and professional guidance is recommended before starting any new medicine. Do not self-medicate without seeking advice first.

Who is eligible to use Biofreeze Pain Relieving Gel?

Biofreeze is suitable for adults and young people aged 12 and over who are experiencing minor muscle or joint pain. It is not suitable for children under 12, or for anyone with broken, infected, or severely inflamed skin at the application site. Those with known allergies to menthol or related compounds should also avoid this product.

What happens if I apply too much Biofreeze Pain Relieving Gel?

Applying more than the recommended amount is unlikely to increase pain relief and may increase the risk of skin irritation or a burning sensation. If you accidentally apply a large amount, wipe off the excess with a clean cloth and rinse the area with cool water. Contact a pharmacist if irritation is significant or does not settle.

How does Biofreeze compare to ibuprofen gel for joint pain?

Biofreeze uses menthol to create a counter-irritation effect, whereas ibuprofen gel works as a non-steroidal anti-inflammatory drug (NSAID) to reduce inflammation at the site. Biofreeze is a useful alternative for people who cannot use NSAIDs — for example, those with a history of stomach ulcers or certain kidney conditions. Both are available over the counter, but they work through entirely different mechanisms.

What are the alternatives to Biofreeze Pain Relieving Gel?

Alternatives include NSAID-based topical gels such as ibuprofen or diclofenac gel, heat-based rubs containing capsaicin, or oral pain relief such as paracetamol or ibuprofen tablets. You can explore a range of options in our creams and ointments collection. The right choice depends on your specific condition, medical history, and any medicines you are already taking.

How long can you use Biofreeze Pain Relieving Gel for?

Biofreeze is intended for short-term use to manage minor, temporary pain. If your symptoms have not improved after seven days of regular use, or if they worsen at any point, you should stop using the product and seek advice from your GP or pharmacist. Prolonged use without medical review is not recommended.

Can I use Biofreeze Pain Relieving Gel on my back?

Yes, Biofreeze is commonly used for minor backache and is suitable for application to the lower or upper back in adults. Apply a small amount to the painful area and massage gently — you may find it easier to ask someone to help you reach the affected spot. If your back pain is severe, persistent, or accompanied by other symptoms such as numbness or bladder changes, seek medical attention promptly.

Is Biofreeze Pain Relieving Gel suitable for arthritis?

Biofreeze can provide temporary relief from the minor joint discomfort associated with arthritis, including osteoarthritis. It does not treat the underlying condition or reduce inflammation in the way that NSAID gels do, but many people find the cooling sensation helpful for day-to-day symptom management. Always discuss your arthritis management plan with your GP for a holistic approach.

What are the latest studies on menthol-based pain relief gels?

Research into topical menthol continues to support its role as a counter-irritant analgesic, with studies confirming its action on TRPM8 cold receptors in the skin. Clinical evidence suggests it is effective for short-term relief of minor musculoskeletal pain, though it is not a substitute for anti-inflammatory treatment where inflammation is the primary driver. Your pharmacist can advise on the most appropriate product for your specific situation.

Can I use Biofreeze Pain Relieving Gel after exercise?

Yes, Biofreeze is widely used by athletes and active individuals to manage post-exercise muscle soreness and stiffness. Apply it to the affected muscles after cooling down and showering, ensuring the skin is clean and dry before application. It is not a substitute for proper warm-up, cool-down, and recovery practices, but it can be a helpful addition to your post-exercise routine.

How Should You Use Biofreeze Pain Relieving Gel?

Using Biofreeze correctly is straightforward, but a few simple steps make a real difference to both comfort and effectiveness. Always read the full product label before your first application, and never apply the gel to broken, damaged, or infected skin.

What Is the Correct Dose of Biofreeze Pain Relieving Gel?

There is no fixed measured dose for topical gels in the same way as oral medicines — the key is to use a small amount sufficient to cover the affected area. Using more gel than necessary does not increase pain relief and may increase the risk of skin irritation.

When Is the Best Time to Use Biofreeze Pain Relieving Gel?

Biofreeze can be used at any time of day when pain or discomfort is present. Many people find it particularly helpful in the morning when joints and muscles tend to feel stiffest, or after physical activity when muscle soreness is at its peak. Applying it before bed may also help ease discomfort that disrupts sleep, though you should allow it to absorb fully before lying down on bedding.

Spacing applications evenly throughout the day — for example, morning, midday, afternoon, and evening — tends to provide more consistent relief than applying multiple times in quick succession.

How Long Can You Use Biofreeze Pain Relieving Gel For?

Biofreeze is designed for short-term use to manage temporary, minor pain. If your symptoms have not improved after seven days of regular use, you should stop using the product and consult your GP or pharmacist. Continuing to use it beyond this point without medical review is not advisable, as persistent pain may indicate an underlying condition that requires proper assessment and treatment.

If your pain is well managed and you are using Biofreeze intermittently — for example, only after exercise — your pharmacist can advise on whether longer-term occasional use is appropriate for your situation.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Based on 1 review
100%
(1)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
J
Jill

Used it for years

What Are the Most Common Side Effects of Biofreeze Pain Relieving Gel?

The majority of people who use Biofreeze experience no significant side effects. The most frequently reported sensation is the expected cooling or tingling feeling at the application site — this is a normal part of how the product works and is not a cause for concern. However, some people may notice mild skin reactions, particularly on first use or if they have sensitive skin.

  • Cooling or tingling sensation at the application site (expected effect)
  • Mild temporary redness of the skin
  • Slight skin irritation or dryness after repeated use

What Are the Less Common Side Effects of Biofreeze Pain Relieving Gel?

Less commonly, some individuals may experience a more pronounced reaction to the menthol or other ingredients in the gel. These reactions are not typical but are worth being aware of before you start using the product. If any of the following occur, stop using Biofreeze and seek advice from a pharmacist.

  • Persistent burning sensation that does not settle after a few minutes
  • Skin rash, hives, or itching at or around the application site
  • Blistering or peeling of the skin
  • Allergic contact dermatitis (a delayed skin reaction)
  • Increased sensitivity to touch at the application site

What Are the Serious Side Effects of Biofreeze Pain Relieving Gel?

Serious side effects from topical menthol products are rare but can occur in the event of a severe allergic reaction (anaphylaxis). This is a medical emergency. If you experience any of the following after applying Biofreeze, call 999 or go to your nearest A&E immediately.

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Sudden drop in blood pressure or feeling faint
  • Widespread skin rash or hives appearing rapidly

What Should You Do If You Experience Side Effects of Biofreeze Pain Relieving Gel?

If you notice mild irritation, remove any excess gel by wiping the area with a clean cloth and rinsing with cool water. Do not apply heat to the area, as this can intensify the menthol sensation. For persistent or worsening reactions, contact your pharmacist or GP. You can also report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Always keep the product away from your eyes. If accidental eye contact occurs, rinse immediately with plenty of cool water and seek medical advice if irritation continues.

Can Biofreeze Pain Relieving Gel Interact With Other Medicines?

No significant drug interactions are currently known for topical menthol at the concentration found in Biofreeze. However, you should avoid applying other topical products — such as other gels, creams, or patches — to the same area at the same time without first checking with your pharmacist. Combining multiple topical products on the same skin area may increase the risk of irritation or unpredictable effects.

If you are using any prescription topical medicines or have a complex medical history, always inform your pharmacist before adding a new topical product to your routine.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery