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Adcal D3

Adcal D3

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  • ✔️ Supports bone density and reduces osteoporosis fracture risk
  • ✔️ Corrects calcium and vitamin D deficiency simultaneously
  • ✔️ Each tablet provides 600 mg calcium and 400 IU vitamin D3
  • ✔️ Chewable fruit-flavoured tablet — no water needed to swallow
  • ✔️ Suitable for adults and children over 12 years of age

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What Is Adcal D3 Calcium Vitamin D Supplement?

 

If you've been told your calcium or vitamin D levels are low, or you're looking to support your bone health as you get older, Adcal D3 is one of the most widely used options available in the UK. The Adcal D3 calcium vitamin D supplement combines two essential nutrients — calcium carbonate and colecalciferol (vitamin D3) — in a single chewable tablet. It's used both to correct existing deficiencies and to help prevent conditions like osteoporosis, particularly in older adults, postmenopausal women, and people with limited sun exposure. You can find it alongside other trusted products in our vitamins and supplements collection.

Calcium and vitamin D work hand in hand. Without adequate vitamin D, your body simply cannot absorb calcium efficiently from food — no matter how much dairy you eat. The NHS recognises that many people in the UK, especially during autumn and winter, do not get enough vitamin D from sunlight alone. Adcal D3 addresses both gaps in one convenient tablet.

 

How Does Adcal D3 Work in the Body?

 

Understanding the mechanism helps you appreciate why both ingredients matter. Here's how Adcal D3 works once you take it:

  • Calcium carbonate (1,500 mg per tablet, providing 600 mg elemental calcium) is released in the stomach and absorbed through the gut wall into the bloodstream.
  • Colecalciferol (400 IU / 10 micrograms of vitamin D3) is absorbed alongside dietary fats and converted in the liver and kidneys into its active form, calcitriol.
  • Calcitriol increases the expression of calcium transport proteins in the intestinal lining, significantly improving how much calcium your body actually absorbs.
  • Calcium then travels to bones and teeth, where it is incorporated into the mineral matrix to maintain density and strength.
  • Calcium also plays a role in muscle contraction, nerve transmission, and blood clotting — so adequate levels matter beyond just bone health.

This dual-action approach means you're not just supplementing calcium in isolation — you're giving your body the tools it needs to actually use it.

 

Who Should Consider Using Adcal D3?

 

Adcal D3 is suitable for a broad range of people, but it's particularly recommended for those at higher risk of calcium or vitamin D deficiency. Your GP or pharmacist may suggest it if you fall into one of the following groups:

  • Postmenopausal women, who are at increased risk of osteoporosis due to falling oestrogen levels
  • Older adults (generally over 65) whose skin is less efficient at synthesising vitamin D from sunlight
  • People with limited sun exposure — including those who cover their skin for cultural or religious reasons
  • Individuals with malabsorption conditions such as coeliac disease or Crohn's disease
  • Those taking corticosteroids long-term, which can reduce bone density over time
  • Adults and children over 12 with a confirmed calcium or vitamin D deficiency

It is not suitable for children under 12, and it should not be used by anyone with hypercalcaemia (raised blood calcium), hypercalciuria (excess calcium in urine), or calcium-containing kidney stones. Always check with your pharmacist if you're unsure whether it's right for you.

 

How Does Adcal D3 Compare to Other Calcium Supplements?

 

Feature Adcal D3 Calcichew D3 Forte
Calcium per tablet 600 mg elemental calcium 500 mg elemental calcium
Vitamin D per tablet 400 IU (10 mcg) 400 IU (10 mcg)
Tablet form Chewable (fruit flavour) Chewable (lemon flavour)
UK classification P (Pharmacy medicine) P (Pharmacy medicine)

 

Is Adcal D3 Safe to Store and Use Long Term?

 

Adcal D3 should be stored below 25°C in a dry place, away from direct sunlight and out of reach of children. The tablets have a pleasant fruit flavour, which makes them easier to take than standard swallowed tablets — particularly useful for older patients who may have difficulty swallowing. As with any supplement, it's worth checking the expiry date on the pack before use.

Long-term use is common, especially in people being treated for or against osteoporosis. However, taking too much calcium or vitamin D over time can lead to hypercalcaemia. If you're taking Adcal D3 alongside other supplements or medicines that also contain calcium or vitamin D, speak to your pharmacist to make sure your total daily intake stays within safe limits. You might also find it helpful to explore our pain relief collection if you're managing musculoskeletal discomfort alongside a bone health regimen.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Adcal D3 specifications
Treatment category Calcium and vitamin D deficiency; osteoporosis prevention
Mechanism of action Provides elemental calcium and colecalciferol to support bone mineralisation and calcium absorption
Effective for Calcium deficiency, vitamin D deficiency, osteoporosis adjunct therapy
Suitable for Adults and children over 12 years
Active ingredients Calcium carbonate 1500 mg (600 mg elemental calcium), Colecalciferol 400 IU (10 mcg)
Pack sizes 56 tablets, 112 tablets
Strengths Calcium 600 mg / Vitamin D3 400 IU per tablet
UK classification P (Pharmacy medicine)
Drug class Calcium and vitamin D supplement
Preparation Chewable tablet
Route of administration Oral

Specifications of Adcal D3

 

What Is Adcal D3 and What Is It Used For?

 

Adcal D3 is a combined calcium and vitamin D supplement available as a chewable tablet. Each tablet contains calcium carbonate 1,500 mg (providing 600 mg of elemental calcium) and colecalciferol 400 IU (10 micrograms of vitamin D3). It is used to treat and prevent calcium and vitamin D deficiency in adults and children over 12 years of age. It is also used as an adjunct — meaning alongside other treatments — in the prevention and management of osteoporosis, where maintaining adequate calcium and vitamin D intake is considered a cornerstone of care.

The NHS recommends that adults consider a daily vitamin D supplement of 10 micrograms, particularly during autumn and winter months when sunlight is insufficient for the skin to produce adequate amounts. Adcal D3 meets this recommendation while simultaneously addressing calcium intake — making it a practical two-in-one option for many patients.

 

What Do You Need to Know Before Using Adcal D3?

 

Before starting Adcal D3, it's important to be aware of the following contraindications and warnings:

  • Do not use if you have hypercalcaemia (abnormally high blood calcium levels)
  • Do not use if you have hypercalciuria (excess calcium in the urine)
  • Do not use if you have calcium-containing kidney stones (nephrolithiasis)
  • Do not use if you have severe renal impairment or renal failure
  • Do not use if you have hypervitaminosis D (vitamin D toxicity)
  • Tell your pharmacist if you have sarcoidosis, as this condition can affect how your body handles vitamin D
  • Tell your pharmacist if you are immobilised for long periods, as this can increase the risk of hypercalcaemia
  • Not recommended for children under 12 years of age

Adcal D3 can interact with a number of other medicines. Always tell your pharmacist or doctor about everything you are taking, including:

  • Tetracycline antibiotics — calcium can reduce their absorption; take Adcal D3 at least two hours before or four to six hours after
  • Bisphosphonates (e.g. alendronic acid) — take at least 30 minutes apart
  • Fluoride supplements — separate by at least three hours
  • Iron supplements — calcium can reduce iron absorption; space doses by at least two hours
  • Thiazide diuretics — may increase the risk of hypercalcaemia when taken with calcium supplements
  • Cardiac glycosides (e.g. digoxin) — hypercalcaemia can increase the risk of toxicity
  • Corticosteroids — may reduce calcium absorption, but this is often why Adcal D3 is prescribed alongside them

 

How Should You Use Adcal D3 Correctly?

 

Always use Adcal D3 exactly as directed by your doctor or pharmacist. The tablets are designed to be chewed — do not swallow them whole. Here's how to take them:

  1. Check the expiry date on the pack before use.
  2. Place one tablet in your mouth and chew it thoroughly.
  3. Swallow after chewing — you do not need water, but a sip can help.
  4. If taking two tablets daily, you can take both at once or split them into morning and evening doses.
  5. If you are taking other medicines, leave a gap of at least two to four hours between Adcal D3 and those medicines.
Indication Age Group Dose Frequency
Calcium & vitamin D deficiency Adults & children over 12 1–2 tablets Once or twice daily as directed
Osteoporosis adjunct Adults 2 tablets Daily (as directed by doctor)

 

What Are the Possible Side Effects of Adcal D3?

 

Like all medicines, Adcal D3 can cause side effects, although not everyone experiences them. Most side effects are mild and related to the digestive system.

Common side effects (may affect up to 1 in 10 people):

  • Constipation
  • Flatulence (wind)
  • Nausea
  • Abdominal pain or discomfort

Less common side effects (may affect up to 1 in 100 people):

  • Hypercalcaemia — symptoms include excessive thirst, frequent urination, confusion, fatigue, and muscle weakness
  • Hypercalciuria — excess calcium in the urine, which can increase kidney stone risk
  • Diarrhoea
  • Skin reactions such as rash or itching (rare)

If you notice symptoms of hypercalcaemia — particularly unusual thirst, confusion, or muscle weakness — stop taking Adcal D3 and contact your GP promptly. You can also browse our women's health collection for additional products relevant to bone health and hormonal wellbeing.

 

How Should You Store Adcal D3 Safely?

 

  • Store below 25°C in a dry place — avoid bathrooms and areas with high humidity
  • Keep away from direct sunlight
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the pack
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Adcal D3 online in the UK?

You can buy Adcal D3 online from Cured Pharmacy, a GPhC-registered UK online pharmacy, without a prescription. It is classified as a Pharmacy (P) medicine, so it is available over the counter. Browse our vitamins and supplements collection for Adcal D3 and related products.

How does Adcal D3 work in the body?

Adcal D3 provides calcium carbonate and colecalciferol (vitamin D3). The vitamin D3 component is converted in the liver and kidneys into its active form, which increases calcium absorption from the gut. The absorbed calcium is then used to maintain bone density, support muscle function, and assist nerve signalling throughout the body.

How do I take Adcal D3 step by step?

Adcal D3 tablets should be chewed thoroughly before swallowing — do not swallow them whole. The usual adult dose is one to two tablets daily, as directed by your doctor or pharmacist. If you are taking other medicines, leave a gap of at least two to four hours between doses to avoid interactions.

What is the best time of day to take Adcal D3?

Adcal D3 can be taken at any time of day, with or without food. If you are taking bisphosphonates such as alendronic acid, take those first thing in the morning on an empty stomach and wait at least 30 minutes before taking Adcal D3. Consistency matters more than timing — try to take it at the same time each day.

What are the side effects of Adcal D3 and how do I manage them?

The most common side effects are constipation, flatulence, nausea, and mild abdominal discomfort. Increasing your fluid intake and dietary fibre can help manage constipation. If you experience symptoms of hypercalcaemia — such as excessive thirst, confusion, or muscle weakness — stop taking the tablets and contact your GP promptly.

Who is eligible to take Adcal D3?

Adcal D3 is suitable for adults and children over 12 years who have calcium or vitamin D deficiency, or who are at risk of osteoporosis. It is particularly recommended for postmenopausal women, older adults, people with limited sun exposure, and those taking long-term corticosteroids. It is not suitable for people with hypercalcaemia, kidney stones, or severe renal impairment.

What happens if I miss a dose of Adcal D3?

If you miss a dose, take it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case skip the missed one. Never take a double dose to compensate for a missed tablet. Simply continue with your regular dosing schedule as normal.

Can I take Adcal D3 if I am pregnant or breastfeeding?

Calcium and vitamin D requirements increase during pregnancy and breastfeeding, but you should not take Adcal D3 without first speaking to your midwife, GP, or pharmacist. The total daily intake of calcium and vitamin D from all sources — including diet and other supplements — must be carefully monitored to avoid exceeding safe limits during pregnancy.

How long do you stay on Adcal D3?

The duration of treatment depends on your individual clinical needs and the advice of your doctor or pharmacist. Some people take Adcal D3 long-term as part of an osteoporosis management plan, while others use it for a defined period to correct a confirmed deficiency. Regular blood tests may be recommended to monitor calcium and vitamin D levels during prolonged use.

What are the alternatives to Adcal D3?

Common alternatives include Calcichew D3 Forte (500 mg calcium / 400 IU vitamin D3) and Calfovit D3 sachets. Separate calcium and vitamin D supplements can also be taken individually if a combined tablet is not suitable. Speak to your pharmacist to find the most appropriate option for your needs and lifestyle.

Does Adcal D3 interact with other medicines?

Yes, Adcal D3 can interact with several medicines including tetracycline antibiotics, bisphosphonates, iron supplements, fluoride, thiazide diuretics, and digoxin. Calcium can reduce the absorption of some of these medicines, so spacing doses by at least two to four hours is usually recommended. Always tell your pharmacist about all medicines and supplements you are taking.

Is Adcal D3 suitable for vegans?

Adcal D3 tablets contain colecalciferol derived from lanolin (sheep's wool), which means they are not suitable for vegans or strict vegetarians. If you follow a vegan diet, speak to your pharmacist about alternative calcium and vitamin D supplements that use plant-derived vitamin D2 or vegan-certified D3 sources. You can also explore our vegan collection for suitable alternatives.

Can I take Adcal D3 with food?

Yes, Adcal D3 can be taken with or without food. Taking it with a meal may help reduce any mild digestive side effects such as nausea. However, if you are also taking medicines that interact with calcium, check with your pharmacist about the best timing relative to meals and other doses.

What are the latest studies on calcium and vitamin D supplementation?

Current evidence supports the use of combined calcium and vitamin D supplementation in reducing fracture risk in older adults, particularly those who are deficient or housebound. The NHS and NICE continue to recommend vitamin D supplementation for at-risk groups throughout the year. Research also highlights the importance of not exceeding recommended daily intakes, as excessive supplementation carries its own risks.

Can Adcal D3 help with muscle weakness or fatigue caused by vitamin D deficiency?

Yes — vitamin D deficiency can cause muscle weakness, fatigue, and bone pain, and correcting the deficiency with a supplement like Adcal D3 may help relieve these symptoms over time. However, improvement is gradual and may take several weeks. If your symptoms are severe or persistent, speak to your GP, who may recommend a blood test to confirm your vitamin D status. You might also find relevant products in our pain relief collection if you are managing associated musculoskeletal discomfort.

How Should You Use Adcal D3?

Adcal D3 tablets are designed to be chewed, not swallowed whole. Taking them correctly ensures you get the full benefit of both the calcium and vitamin D they contain. Follow these steps each time you take a dose:

What Is the Correct Dose of Adcal D3?

The dose of Adcal D3 depends on your age and the reason you are taking it. Always follow the instructions given by your doctor or pharmacist. The table below provides a general guide based on standard clinical recommendations.

When Is the Best Time to Use Adcal D3?

There is no single "best" time to take Adcal D3 — what matters most is taking it consistently at the same time each day. If you are also taking bisphosphonates such as alendronic acid, those should be taken first thing in the morning on an empty stomach, with Adcal D3 taken at least 30 minutes later. Taking Adcal D3 with or after a meal may help reduce any mild digestive discomfort, particularly if you are prone to nausea.

How Long Can You Use Adcal D3 For?

The length of time you take Adcal D3 depends entirely on your individual clinical situation. For people managing osteoporosis or taking long-term corticosteroids, treatment is often ongoing and reviewed regularly by a GP. For those correcting a short-term deficiency, a defined course may be recommended. Your doctor or pharmacist may arrange periodic blood tests to check your calcium and vitamin D levels during prolonged use, ensuring your intake remains within safe limits.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Adcal D3?

Most people tolerate Adcal D3 well, but some do experience mild digestive side effects, particularly when first starting treatment. These are generally not serious and often settle as your body adjusts.

  • Constipation
  • Flatulence (wind)
  • Nausea
  • Mild abdominal pain or bloating

What Are the Less Common Side Effects of Adcal D3?

Less commonly, some people may experience side effects related to elevated calcium levels in the blood or urine. These are more likely if you are taking other calcium-containing products at the same time, or if you have an underlying condition affecting calcium metabolism.

  • Hypercalcaemia — symptoms include excessive thirst, frequent urination, fatigue, confusion, and muscle weakness
  • Hypercalciuria — excess calcium in the urine, which may increase the risk of kidney stones
  • Diarrhoea
  • Vomiting

What Are the Serious Side Effects of Adcal D3?

Serious side effects from Adcal D3 are rare when the product is used as directed. However, hypercalcaemia — if left untreated — can become clinically significant. Symptoms to watch for include severe confusion, irregular heartbeat, extreme muscle weakness, and loss of consciousness. Allergic reactions are very rare but can include skin rash, itching, swelling of the face or throat, and difficulty breathing. If you experience any of these, seek emergency medical attention immediately.

What Should You Do If You Experience Side Effects?

If you develop mild digestive side effects such as constipation or wind, try increasing your fluid and dietary fibre intake. Taking Adcal D3 with food may also help reduce nausea. If you suspect you are experiencing hypercalcaemia — particularly unusual thirst, confusion, or muscle weakness — stop taking the tablets and contact your GP as soon as possible. Do not restart without medical advice.

Can Adcal D3 Interact With Other Medicines?

Yes. Adcal D3 can affect the absorption and activity of several other medicines. Calcium can bind to tetracycline antibiotics, bisphosphonates, iron supplements, and fluoride in the gut, reducing their effectiveness. Thiazide diuretics can increase the risk of hypercalcaemia when taken alongside calcium supplements. Digoxin toxicity risk may increase if blood calcium levels rise. Always inform your pharmacist or GP of all medicines and supplements you are taking before starting Adcal D3.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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