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Active Iron Advance 25mg - 30 Capsules

Active Iron Advance 25mg - 30 Capsules

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  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Provides 25mg elemental iron per capsule daily
  • ✔️ Ferrous bisglycinate form is gentler on the stomach
  • ✔️ Supports red blood cell formation and reduces fatigue
  • ✔️ Ideal for women with heavy periods or low dietary iron
  • ✔️ One month's supply in every 30-capsule pack

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Is Active Iron Advance 25mg the Right Iron Supplement for Women?

 

Iron deficiency is one of the most common nutritional shortfalls in the UK, particularly among women of childbearing age. The NHS estimates that around one in ten women aged 16 to 64 may have low iron stores, often linked to menstruation, pregnancy, or an inadequate dietary intake. If you've been feeling persistently tired, breathless, or struggling to concentrate, your iron levels could be playing a role. Active Iron Advance 25mg is a carefully formulated iron supplement for women designed to deliver 25mg of elemental iron per capsule in a form that's gentler on the digestive system than many standard iron tablets.

Each pack contains 30 capsules — a full month's supply at the standard daily dose. You'll find it alongside other vitamins and supplements at Cured Pharmacy, where every product is reviewed by our qualified pharmacy team before being made available to buy.

 

How Does Active Iron Advance 25mg Work in the Body?

 

The active ingredient in Active Iron Advance 25mg is ferrous bisglycinate — a chelated form of iron where the iron molecule is bound to two glycine amino acids. This structure protects the iron from interacting with other compounds in the gut, which is one reason it tends to cause fewer gastrointestinal side effects than ferrous sulphate. Once ingested, the iron is absorbed primarily in the duodenum and upper small intestine.

  • Iron is incorporated into haemoglobin, the protein in red blood cells that carries oxygen around the body.
  • It supports myoglobin production in muscle tissue, which stores and releases oxygen during physical activity.
  • Adequate iron levels contribute to normal energy-yielding metabolism and help reduce tiredness and fatigue.
  • Iron also plays a role in supporting normal immune function and cognitive performance.

 

Who Should Consider Using Active Iron Advance 25mg?

 

This supplement is particularly suited to adults who have been advised by a healthcare professional that their iron levels are low, or who are at higher risk of deficiency. It is not a treatment for diagnosed iron deficiency anaemia on its own — if you suspect anaemia, please speak to your GP first. That said, it can be a useful daily supplement for those with increased iron requirements or dietary gaps.

  • Women with heavy menstrual periods who lose significant iron each month.
  • Pregnant or breastfeeding women with increased nutritional demands (always consult your midwife or GP first).
  • Vegetarians and vegans whose diets may be lower in haem iron from animal sources.
  • People recovering from illness, surgery, or blood loss who need to rebuild iron stores.

 

How Does Active Iron Advance 25mg Compare to Standard Iron Tablets?

 

Feature Active Iron Advance 25mg Ferrous Sulphate 200mg (standard)
Elemental iron per dose 25mg Approximately 65mg
Iron form Ferrous bisglycinate (chelated) Ferrous sulphate (inorganic salt)
GI tolerability Generally better tolerated More likely to cause nausea and constipation
Prescription required No — available OTC Often prescribed by GP

 

Is Active Iron Advance 25mg Suitable for Everyday Use?

 

For most healthy adults with low-to-moderate iron requirements, one capsule daily is appropriate as a maintenance supplement. Because ferrous bisglycinate is absorbed more efficiently than some other iron forms, a lower elemental dose can still be effective — making this a practical choice if you've previously found higher-dose iron tablets hard on your stomach. If you're also managing other aspects of your health, you might find it helpful to explore our women's health range for complementary products.

Store capsules below 25°C in a dry place, away from direct sunlight and out of reach of children. Do not use beyond the printed expiry date.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Active Iron Advance 25mg - 30 Capsules specifications
Treatment category Iron deficiency; nutritional supplementation
Mechanism of action Chelated ferrous bisglycinate absorbed in the small intestine to replenish iron stores and support haemoglobin synthesis
Effective for Reducing tiredness and fatigue associated with low iron; supporting red blood cell formation and immune function
Suitable for Adults including women of childbearing age, vegetarians, vegans, and those with increased iron requirements
Active ingredient Ferrous bisglycinate providing 25mg elemental iron
Pack size 30 capsules
Strength 25mg elemental iron per capsule
UK classification General Sale / Food supplement
Drug class Iron supplement (chelated)
Preparation Hard capsule
Route of administration Oral

Specifications of Active Iron Advance 25mg - 30 Capsules

 

What Is Active Iron Advance 25mg and What Is It Used For?

 

Active Iron Advance 25mg is an oral iron supplement containing ferrous bisglycinate as its active ingredient, providing 25mg of elemental iron per capsule. It is used to help maintain healthy iron levels in adults, particularly those at risk of dietary iron deficiency. Iron is an essential mineral that the body cannot produce on its own — it must come from food or supplementation.

The NHS identifies iron as necessary for the production of haemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. Without sufficient iron, you may experience symptoms such as persistent tiredness, pale skin, shortness of breath, and difficulty concentrating. This supplement is intended to support those with low dietary iron intake or increased physiological demands, not to replace medical treatment for diagnosed iron deficiency anaemia.

 

What Do You Need to Know Before Using Active Iron Advance 25mg?

 

Before starting any iron supplement, it's important to consider whether it's appropriate for your individual circumstances. Do not take this product if any of the following apply to you:

  • You have haemochromatosis (iron overload disorder) or another condition causing excess iron storage.
  • You have a known hypersensitivity to any of the ingredients.
  • You have been diagnosed with haemolytic anaemia or aplastic anaemia without confirmed iron deficiency.
  • You are a child under 12 years of age — keep all iron supplements out of reach of children, as accidental overdose can be fatal.

The following medicines may interact with iron supplements. Separate doses by at least two hours where possible:

  • Antacids and proton pump inhibitors — may reduce iron absorption.
  • Tetracycline and quinolone antibiotics — iron can reduce their absorption and effectiveness.
  • Levothyroxine (thyroid medication) — iron may reduce its absorption; take at least four hours apart.
  • Calcium supplements and dairy products — can inhibit iron uptake when taken simultaneously.
  • Levodopa (used in Parkinson's disease) — iron may reduce its absorption.

 

How Should You Use Active Iron Advance 25mg?

 

Follow these steps to get the most from your supplement and minimise the risk of side effects:

  1. Take one capsule daily, unless otherwise directed by your GP or pharmacist.
  2. Swallow the capsule whole with a full glass of water.
  3. Take on an empty stomach if possible, as iron is absorbed more efficiently without food.
  4. If you experience nausea or stomach discomfort, take with a small amount of food — avoid dairy, tea, or coffee at the same time.
  5. Do not crush or chew the capsule.
  6. Try to take it at the same time each day to build a consistent routine.
Indication Age Group Dose Frequency
Dietary iron supplementation Adults (18+) 1 capsule (25mg elemental iron) Once daily
Pregnancy (under medical supervision) Adults As directed by midwife or GP Once daily
Children under 12 Under 12 Not recommended

 

What Are the Possible Side Effects of Active Iron Advance 25mg?

 

Like all supplements and medicines, iron capsules can cause side effects in some people. Ferrous bisglycinate is generally considered gentler on the gut than ferrous sulphate, but side effects are still possible. If you're also managing digestive health concerns, you may find our IBS and cramps range helpful alongside your supplement routine.

Common side effects (may affect up to 1 in 10 people):

  • Nausea or stomach discomfort, particularly when taken on an empty stomach.
  • Constipation or changes in bowel habits.
  • Dark or black-coloured stools — this is harmless and expected with iron supplementation.
  • Mild abdominal cramping.

Less common side effects (may affect fewer than 1 in 100 people):

  • Diarrhoea or loose stools.
  • Heartburn or indigestion.
  • Vomiting in sensitive individuals.
  • Allergic reactions such as skin rash or itching — stop use and seek medical advice if this occurs.

 

How Should You Store Active Iron Advance 25mg?

 

Correct storage helps maintain the quality and safety of your supplement throughout its shelf life. Follow these guidelines:

  • Store below 25°C in a cool, dry place away from direct sunlight and moisture.
  • Do not store in the bathroom or near a heat source such as a radiator.
  • Keep the capsules in their original packaging until use.
  • Keep out of sight and reach of children at all times — iron overdose in children is a medical emergency.
  • Do not use after the expiry date printed on the pack.
  • Do not dispose of medicines via wastewater or household waste — return unused capsules to your local pharmacy for safe disposal.

If you have any concerns about storage or product integrity, speak to your pharmacist before use. For a broader range of health support products, explore our vitamins and supplements collection.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Active Iron Advance 25mg online in the UK?

You can buy Active Iron Advance 25mg directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter supplement. You'll find it alongside other products in our vitamins and supplements collection, with fast UK delivery available.

How does Active Iron Advance 25mg work in the body?

Active Iron Advance 25mg uses ferrous bisglycinate, a chelated form of iron where the mineral is bound to glycine amino acids, protecting it from interference by other gut compounds. This allows it to be absorbed efficiently in the small intestine, where it enters the bloodstream and is used to produce haemoglobin and support oxygen transport. The result is improved energy levels and reduced fatigue associated with low iron stores.

How do I take Active Iron Advance 25mg step by step?

Take one capsule daily, swallowed whole with a full glass of water. Ideally, take it on an empty stomach for best absorption, but if you experience nausea, a small amount of food can help. Avoid taking it alongside tea, coffee, dairy, or antacids, as these can reduce how much iron your body absorbs.

What is the best time of day to take Active Iron Advance 25mg?

Morning on an empty stomach is often recommended, as iron absorption tends to be higher when the stomach is not full of food. However, consistency matters more than timing — taking it at the same time each day helps you build a reliable habit. If morning doses cause stomach upset, try taking it mid-morning with a light snack instead.

What are the side effects of Active Iron Advance 25mg and how do I manage them?

The most common side effects include nausea, constipation, and dark-coloured stools — the latter is harmless and expected. Ferrous bisglycinate is generally better tolerated than ferrous sulphate, so these effects are often milder. If constipation is a concern, increasing your fluid and fibre intake can help; if nausea persists, try taking the capsule with a small meal.

Who is eligible to take Active Iron Advance 25mg?

This supplement is suitable for adults aged 18 and over, including women with heavy periods, vegetarians, vegans, and those with increased iron requirements due to pregnancy or recovery from illness. It is not suitable for people with haemochromatosis, iron overload conditions, or children under 12. If you are pregnant, always check with your midwife or GP before starting any supplement.

What happens if I miss a dose of Active Iron Advance 25mg?

If you forget to take your capsule, take it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case simply skip the missed one. Never take two capsules at once to compensate for a missed dose. Continuing your regular daily routine is the most important thing for maintaining consistent iron levels.

How long should I take Active Iron Advance 25mg for?

The appropriate duration depends on why you're taking it. For general dietary supplementation, many people take it ongoing, particularly if their diet is consistently low in iron-rich foods. If you've been advised to take iron to address a deficiency, the NHS recommends continuing for several months after levels normalise to fully replenish your body's iron stores. Your GP or pharmacist can advise on the right duration for your situation.

Is Active Iron Advance 25mg safe to take during pregnancy?

Iron requirements increase significantly during pregnancy, and the NHS recommends that pregnant women ensure adequate iron intake throughout. However, you should always consult your midwife or GP before starting any supplement during pregnancy, as they may recommend a specific dose or formulation based on your blood results. Do not self-diagnose iron deficiency during pregnancy — a blood test is the only reliable way to confirm your levels.

Can vegetarians and vegans take Active Iron Advance 25mg?

Yes — this supplement is particularly relevant for vegetarians and vegans, as plant-based diets contain only non-haem iron, which is absorbed less efficiently than the haem iron found in meat and fish. Ferrous bisglycinate is a non-animal-derived iron source, making it suitable for plant-based diets. Check the product label to confirm suitability if you follow a strict vegan lifestyle, as capsule shells may vary.

What medicines interact with Active Iron Advance 25mg?

Iron can interact with several medicines, including tetracycline and quinolone antibiotics, levothyroxine, levodopa, and antacids — all of which should be taken at least two hours apart from your iron capsule. Calcium supplements and dairy products can also reduce iron absorption when taken at the same time. Always tell your pharmacist about all medicines and supplements you are taking before starting Active Iron Advance 25mg.

What are the alternatives to Active Iron Advance 25mg?

Common alternatives include ferrous sulphate tablets (often prescribed by GPs for diagnosed iron deficiency anaemia), ferrous fumarate, and other chelated iron supplements such as iron glycinate. Ferrous sulphate provides a higher elemental iron dose but is more likely to cause gastrointestinal side effects. Your GP or pharmacist can help you choose the most appropriate option based on your iron levels and tolerance.

Will Active Iron Advance 25mg make my stools black?

Yes — dark or black-coloured stools are a well-known and harmless effect of iron supplementation. This happens because unabsorbed iron reacts with compounds in the gut, changing stool colour. It is not a sign of internal bleeding or a cause for concern in the context of iron supplementation. However, if you notice black tarry stools and are not taking iron, seek medical advice promptly as this can indicate a more serious issue.

What are the latest findings on ferrous bisglycinate versus other iron forms?

Published research suggests that chelated iron forms such as ferrous bisglycinate are absorbed comparably to or better than ferrous sulphate in some populations, with a significantly lower incidence of gastrointestinal side effects. This makes them a practical option for people who have previously struggled to tolerate standard iron tablets. Ongoing research continues to explore optimal iron supplementation strategies, particularly for women and those with inflammatory conditions that affect iron metabolism.

Can I take Active Iron Advance 25mg alongside vitamin C?

Yes — vitamin C (ascorbic acid) is known to enhance non-haem iron absorption by converting ferric iron to the more readily absorbed ferrous form in the gut. Taking your iron capsule with a small glass of orange juice or a vitamin C supplement at the same time may help improve how much iron your body absorbs. This is a commonly recommended strategy, particularly for vegetarians and vegans whose diets rely on non-haem iron sources. You can explore our women's health range for complementary nutritional support products.

How Should You Use Active Iron Advance 25mg?

Using this supplement correctly makes a real difference to how well your body absorbs the iron. Follow these steps each day to get the most from each capsule and reduce the chance of any stomach discomfort.

What Is the Correct Dose of Active Iron Advance 25mg?

The standard adult dose is one capsule per day, providing 25mg of elemental iron. This dose is appropriate for most adults using the supplement to maintain healthy iron levels or address a dietary shortfall. If your GP has recommended a higher iron intake for diagnosed deficiency, they may advise a different regimen — always follow their specific guidance over general label instructions.

When Is the Best Time to Use Active Iron Advance 25mg?

Iron absorption is generally highest when taken on an empty stomach, so first thing in the morning — before breakfast — is often the most effective time. Taking it with a small glass of orange juice can further enhance absorption, as vitamin C helps convert iron into a more readily absorbed form. If morning doses consistently cause nausea, mid-morning with a light, dairy-free snack is a reasonable alternative.

Avoid taking your capsule at the same time as tea, coffee, milk, or calcium-containing foods, as these can significantly reduce how much iron your body takes up. Similarly, if you take levothyroxine or certain antibiotics, leave a gap of at least two to four hours between those medicines and your iron capsule.

How Long Can You Use Active Iron Advance 25mg For?

For general dietary supplementation, Active Iron Advance 25mg can be taken on an ongoing basis, particularly if your diet is consistently low in iron-rich foods. If you are taking it to address a confirmed iron deficiency, the NHS advises continuing supplementation for several months after your iron levels return to normal, in order to fully replenish your body's iron stores. Regular blood tests arranged by your GP are the most reliable way to monitor your progress and determine when supplementation is no longer needed.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Active Iron Advance 25mg?

Iron supplements can cause digestive side effects in some people, though ferrous bisglycinate — the form used in Active Iron Advance 25mg — is generally considered gentler on the gut than ferrous sulphate. Most side effects are mild and tend to improve as your body adjusts over the first one to two weeks of use.

  • Nausea or stomach discomfort, particularly when taken on an empty stomach.
  • Constipation or a feeling of bloating.
  • Dark or black-coloured stools — this is harmless and a normal consequence of iron supplementation.
  • Mild abdominal cramping or a feeling of fullness.

What Are the Less Common Side Effects of Active Iron Advance 25mg?

Less frequently, some people may experience more noticeable digestive disturbance. These effects are still generally mild but worth being aware of before you start.

  • Diarrhoea or loose stools.
  • Heartburn or acid reflux symptoms.
  • Vomiting, particularly in those with a sensitive stomach.
  • Skin rash, itching, or hives — which may indicate a sensitivity to one of the ingredients.

What Are the Serious Side Effects of Active Iron Advance 25mg?

Serious side effects from iron supplementation at standard doses are rare in adults. However, iron overdose is a medical emergency — particularly in children, where even a small number of adult-strength capsules can be life-threatening. Symptoms of iron overdose include severe abdominal pain, vomiting blood, bloody diarrhoea, drowsiness, and collapse. If you suspect an overdose, call 999 or go to your nearest A&E immediately.

Signs of an allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — require urgent medical attention. Stop taking the supplement and seek help straight away if these occur.

What Should You Do If You Experience Side Effects of Active Iron Advance 25mg?

For mild side effects such as nausea or constipation, try taking the capsule with a small amount of food rather than on an empty stomach. Increasing your daily water intake and eating more fibre-rich foods can help manage constipation. If side effects persist beyond two weeks or become difficult to tolerate, speak to your pharmacist — they may suggest an alternative iron formulation or a different dosing schedule that suits you better.

You can report suspected side effects from food supplements to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of products available in the UK.

Can Active Iron Advance 25mg Interact With Other Medicines?

Yes — iron can interact with a number of commonly used medicines, reducing either the iron's absorption or the effectiveness of the other medicine. The most clinically significant interactions include tetracycline and quinolone antibiotics, levothyroxine (thyroid hormone replacement), levodopa (used in Parkinson's disease), and antacids or proton pump inhibitors. Calcium supplements and dairy products can also reduce iron uptake when taken at the same time. As a general rule, separate your iron capsule from any interacting medicine by at least two hours — and up to four hours for levothyroxine. Always inform your pharmacist of all medicines and supplements you are currently taking.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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