Wegovy vs Mounjaro UK - Compare Prices & Cheapest Option

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Wegovy vs Mounjaro - Compare Prices & Cheapest Option

Compare Wegovy vs Mounjaro at the cheapest UK price — Wegovy from £124.99 Mounjaro from £124.99 plus £20 off with code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Wegovy vs Mounjaro: Which Weight Loss Treatment Is Right for You?

When comparing wegovy vs mounjaro, both are highly effective GLP-1 receptor agonist injections licensed by the MHRA for chronic weight management in adults with obesity or overweight with weight-related comorbidities. Mounjaro (tirzepatide) offers dual GIP/GLP-1 action, whilst Wegovy (semaglutide) targets GLP-1 receptors alone. Both require clinical assessment by a UK prescriber and have demonstrated substantial weight loss in landmark trials, but they differ in mechanism, efficacy data, dosing schedules, and cost.

How Do Wegovy vs Mounjaro Work Differently?

Understanding the mechanism behind wegovy vs mounjaro helps clarify why outcomes differ. Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics the incretin hormone GLP-1, which regulates appetite, slows gastric emptying, and enhances insulin secretion [1]. Mounjaro contains tirzepatide, the first dual GIP/GLP-1 receptor agonist, targeting both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 pathways simultaneously [2]. This dual action may amplify metabolic effects and appetite suppression beyond GLP-1 alone.

In clinical practice, this mechanistic difference translates to potentially greater weight reduction with Mounjaro in head-to-head comparisons. The SURPASS-2 trial directly compared tirzepatide with semaglutide 1mg in type 2 diabetes patients, showing superior glycaemic control and weight loss with tirzepatide [3]. Both medications require subcutaneous injection once weekly, are subject to prescriber approval, and carry similar gastrointestinal side effect profiles, though individual tolerance varies.

Wegovy vs Mounjaro Efficacy: What the Clinical Trials Show

The evidence base for wegovy vs mounjaro efficacy is robust but derived from separate trial programmes. Wegovy's STEP 1 trial demonstrated an average weight loss of 14.9% body weight over 68 weeks in adults with obesity, compared to 2.4% with placebo [1]. Participants received semaglutide 2.4mg weekly alongside lifestyle intervention, with two-thirds achieving at least 10% weight reduction.

Mounjaro's SURMOUNT-1 trial evaluated tirzepatide specifically for weight management in adults without diabetes, showing average weight reductions of 15.0% (5mg), 19.5% (10mg), and 20.9% (15mg) over 72 weeks, compared to 3.1% with placebo [4]. These results suggest tirzepatide may deliver incrementally greater weight loss at higher doses, though direct comparison is limited by differing trial populations and protocols. Both treatments require ongoing use to maintain weight loss, and efficacy depends on adherence to dosing and lifestyle modification.

Average Weight Loss Outcomes

When evaluating wegovy vs mounjaro for expected outcomes, Wegovy users in clinical trials lost an average of 15kg over 68 weeks, whilst Mounjaro users lost up to 22kg at the highest dose over 72 weeks [1][4]. Individual results vary based on baseline BMI, adherence, diet quality, and physical activity levels. Both medications are licensed for long-term use and work best when combined with a reduced-calorie diet and increased physical activity, as recommended by NICE guidance.

Side Effects: Wegovy vs Mounjaro Tolerability

The side effect profiles of wegovy vs mounjaro are broadly similar, reflecting their shared GLP-1 mechanism. The most common adverse events for both are gastrointestinal: nausea, diarrhoea, vomiting, constipation, and abdominal discomfort [1][2]. These symptoms typically emerge during dose escalation and diminish over time as the body adapts. Starting at a low dose and titrating gradually, as per licensed schedules, minimises these effects.

Serious but rare risks include pancreatitis, gallbladder disease, and thyroid C-cell tumours (observed in rodent studies, relevance to humans unclear). Both medications carry a boxed warning in some jurisdictions regarding thyroid tumours and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Prescribers assess medical history during consultation to ensure suitability. Patients should report persistent abdominal pain, jaundice, or neck swelling immediately.

Feature Wegovy Mounjaro
Active Ingredient Semaglutide Tirzepatide
Mechanism GLP-1 receptor agonist Dual GIP/GLP-1 receptor agonist
Dosing Frequency Once weekly injection Once weekly injection
Maintenance Dose 2.4mg weekly Up to 15mg weekly
Average Weight Loss (trials) 14.9% over 68 weeks Up to 20.9% over 72 weeks
Starting Price (UK) From £89.00/month From £145.00/month
Common Side Effects Nausea, diarrhoea, vomiting Nausea, diarrhoea, vomiting
Prescription Required Yes (UK prescriber) Yes (UK prescriber)

Dosing Schedules: Wegovy vs Mounjaro Administration

Dosing regimens differ slightly when comparing wegovy vs mounjaro, though both are once-weekly subcutaneous injections. Wegovy starts at 0.25mg weekly, increasing monthly through 0.5mg, 1mg, 1.7mg, to a maintenance dose of 2.4mg [1]. This gradual escalation over 16-20 weeks reduces gastrointestinal side effects and improves tolerability.

Mounjaro begins at 2.5mg weekly, increasing every four weeks through 5mg, 7.5mg, 10mg, to a maximum of 15mg if additional glycaemic or weight control is needed [2]. The starting dose is higher than Wegovy's, but still designed to minimise adverse events. Both medications are supplied in pre-filled, single-use injection pens for ease of self-administration. Patients inject into the abdomen, thigh, or upper arm, rotating sites to prevent lipodystrophy.

Which Dosing Schedule Suits You?

Choosing between wegovy vs mounjaro dosing depends on individual tolerance and clinical response. Wegovy's slower titration may suit those with sensitive gastrointestinal systems, whilst Mounjaro's flexible dosing up to 15mg offers scope for greater weight loss if tolerated. Your prescriber will tailor the schedule based on your medical history, current medications, and weight loss goals. Both regimens require commitment to weekly injections and regular follow-up to monitor progress and side effects.

Cost Comparison: Wegovy vs Mounjaro UK Pricing

Affordability is a key factor when deciding between wegovy vs mounjaro in the UK. At Cured Pharmacy, Mounjaro is available from £124.99 per month, subject to prescriber approval following a free online consultation under three minutes. Wegovy starts from £124.99 per month, making it the more budget-friendly option for many patients. New customers can Save £20 off their first order with code Weightlossnew, bringing the entry price down further.

Whilst Mounjaro may offer incrementally greater weight loss in some trials, the higher cost must be weighed against individual budget and expected benefit. Wegovy delivers clinically significant weight reduction at a lower price point, and for many patients represents the optimal balance of efficacy and affordability. Both medications are not currently available on the NHS for weight management alone in most areas, so private prescription is the primary route. Cured Pharmacy guarantees the lowest UK prices with transparent upfront costs and discreet next-day delivery.

Who Should Choose Wegovy vs Mounjaro?

The decision between wegovy vs mounjaro should be guided by clinical suitability, personal preference, and cost. Mounjaro may be preferred for patients seeking maximum weight loss potential and who can tolerate higher doses, particularly those with type 2 diabetes already benefiting from dual GIP/GLP-1 action [3]. Wegovy is ideal for patients prioritising proven efficacy at a lower cost, or those new to GLP-1 therapy who prefer a gentler dose escalation.

Both treatments require a BMI of 30 kg/m² or above, or 27 kg/m² with at least one weight-related comorbidity such as hypertension, dyslipidaemia, or obstructive sleep apnoea, in line with MHRA licensing. Contraindications include pregnancy, breastfeeding, type 1 diabetes, diabetic ketoacidosis, severe gastrointestinal disease, and personal or family history of medullary thyroid carcinoma. A UK prescriber will assess your medical history, current medications, and weight loss goals during the online consultation to determine the most appropriate treatment.

Switching Between Wegovy vs Mounjaro

Some patients start with Wegovy and later switch to Mounjaro if weight loss plateaus or additional efficacy is desired. Conversely, others may step down from Mounjaro to Wegovy to reduce costs once target weight is approached. Switching should always be supervised by a prescriber, with careful attention to dosing equivalence and monitoring for side effects during transition. Cured Pharmacy's clinical team can advise on safe switching protocols and provide ongoing support throughout your weight loss journey.

Scientific References

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., ... & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  2. Frias, J. P., Davies, M. J., Rosenstock, J., Pérez Manghi, F. C., Fernández Landó, L., Bergman, B. K., ... & Jastreboff, A. M. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. New England Journal of Medicine, 385(6), 503-515. [accessed 15 August 2026]
  3. Frías, J. P., Davies, M. J., Rosenstock, J., Pérez Manghi, F. C., Fernández Landó, L., Bergman, B. K., ... & SURPASS-2 Investigators. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes (SURPASS-2): a randomised, open-label, phase 3 trial. The Lancet, 398(10295), 64-77. [accessed 15 August 2026]
  4. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., Wharton, S., Connery, L., Alves, B., ... & Garvey, W. T. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. [accessed 15 August 2026]
  5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

Trusted by thousands

Real people, real results

Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Which is better for weight loss, Wegovy vs Mounjaro?
Mounjaro showed slightly higher average weight loss in trials (up to 20.9% vs 14.9% for Wegovy), but both are highly effective and choice depends on individual response, tolerability, and budget.
Can I switch from Wegovy to Mounjaro or vice versa?
Yes, switching between wegovy vs mounjaro is possible under prescriber supervision, with careful dose adjustment and monitoring for side effects during transition.
Is Mounjaro worth the extra cost compared to Wegovy?
Mounjaro may deliver incrementally greater weight loss, but Wegovy offers proven efficacy at a lower price (from £124.99 vs £124.99), making it excellent value for most patients.
Do Wegovy and Mounjaro have the same side effects?
Both wegovy vs mounjaro share similar gastrointestinal side effects (nausea, diarrhoea, vomiting) due to their GLP-1 mechanism, though individual tolerance varies.
How quickly do Wegovy vs Mounjaro work?
Both treatments begin reducing appetite within the first week, with measurable weight loss typically seen by week 4-8 and maximum effect achieved over 16-20 months with dose escalation.
Can I use Wegovy or Mounjaro if I have type 2 diabetes?
Yes, both are licensed for weight management in adults with or without type 2 diabetes, though Mounjaro's dual GIP/GLP-1 action may offer additional glycaemic benefits.
Are Wegovy and Mounjaro available on the NHS?
NHS availability for weight management is limited and varies by region. Most patients access wegovy vs mounjaro via private prescription from UK-registered pharmacies like Cured Pharmacy.
How long do I need to take Wegovy or Mounjaro?
Both are intended for long-term use. Weight loss is maintained with ongoing treatment, but may return if medication is stopped, so continued use alongside lifestyle changes is recommended.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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