Can You Take Vardenafil and Felodipine Together?
Learn how these medicines interact and what your UK prescriber checks before treatment.
Takes less than 2 minutes to complete 100% online
ED Treatments We Offer
Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.
Trusted by thousands
Real people, real results
“Fabulous service and quick delivery”
“Felt the effects of these after about 5 days. Erections are better and can get aroused and ready easier”
“Excellent value and brilliant customer service”
“I received excellent service and everything went well. The order arrived quickly and in perfect condition. It's working very well! Thank you to the whole team for the great work!”
“Delivery was good, the product lived up to expectations.”
How Our Online Service Works
Choose your treatment
Select from our recommended UK-licensed medications.
Answer quick questions
Select safe UK treatments. Quick answers.
Get it delivered fast
We will deliver direct to you as quickly as tomorrow.
Vardenafil and Felodipine: Understanding the Interaction
Published: 30 October 2026
Many men wonder whether vardenafil and felodipine can be taken together safely. Vardenafil (generic Levitra) is a prescription medicine used to treat erectile dysfunction, while felodipine is a calcium channel blocker prescribed for high blood pressure and angina. The good news is that these two medicines can usually be used together, but there are important safety considerations your prescriber will check before treatment begins.
Start Low, Go Slow
If your prescriber approves vardenafil with felodipine, they will likely recommend starting with the lowest dose (5mg) to minimise the risk of low blood pressure. Be cautious when standing up, and avoid heavy alcohol to reduce dizziness.
What Is Vardenafil and How Does It Work?
Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor licensed in the UK for treating erectile dysfunction [5]. It works by relaxing the blood vessels in the penis, allowing increased blood flow when you are sexually aroused. Vardenafil is available in 5mg, 10mg and 20mg tablets and is usually taken about 25 to 60 minutes before sexual activity [5].
The medicine does not cause an erection on its own—sexual stimulation is still needed. Effects typically last for around four to five hours, and you should not take more than one dose in 24 hours [5]. Like all PDE5 inhibitors, vardenafil can lower blood pressure slightly, which is why interactions with other blood-pressure medicines need careful consideration.
At Cured Pharmacy, vardenafil is available on prescription after an online consultation with a UK-registered prescriber. The consultation ensures the medicine is suitable for you, taking into account all your current medications and health conditions.
What Is Felodipine and Why Is It Prescribed?
Felodipine belongs to a group of medicines called calcium channel blockers (also known as calcium antagonists). It is commonly prescribed to treat high blood pressure (hypertension) and to prevent angina (chest pain caused by reduced blood flow to the heart). Felodipine works by relaxing and widening blood vessels, which lowers blood pressure and reduces the workload on the heart.
This medicine is usually taken once daily as a modified-release tablet, often in doses ranging from 2.5mg to 10mg. Because felodipine lowers blood pressure, combining it with other medicines that also affect blood pressure—such as vardenafil—requires careful monitoring to avoid excessive drops in blood pressure that could cause dizziness or fainting.
If you have been prescribed felodipine, it is important to tell your prescriber during any consultation for erectile dysfunction treatment. This allows them to assess whether vardenafil or another ED medicine is appropriate for you, and to recommend the safest starting dose.
Other Calcium Channel Blockers
Felodipine is one of several calcium channel blockers. Others include amlodipine, nifedipine, diltiazem, verapamil, lacidipine, lercanidipine and nicardipine. All work in similar ways to lower blood pressure and may have comparable interactions with vardenafil. Your prescriber will consider whichever calcium channel blocker you are taking when assessing your suitability for ED treatment.
How Do Vardenafil and Felodipine Interact?
Both vardenafil and felodipine can lower blood pressure, so taking them together may add to this blood-pressure-lowering effect. In plain English, this means that the combination could potentially cause your blood pressure to drop more than either medicine would on its own. This can lead to symptoms such as dizziness, light-headedness, fainting, or feeling unsteady when you stand up.
However, this interaction is usually manageable and does not mean the two medicines cannot be used together. Most men who are stable on felodipine and whose blood pressure is well controlled can safely take vardenafil, provided their prescriber has reviewed their full medical history and current medication list [5]. The key is to start with the lowest effective dose of vardenafil and to monitor for any symptoms of low blood pressure.
It is important to understand that this interaction is different from the dangerous combinations with nitrates, nicorandil or riociguat, which are absolute contraindications. Felodipine does not fall into that category, and the interaction is one of caution and dose adjustment rather than prohibition.
What you need to know
- Vardenafil and felodipine can usually be taken together safely with prescriber approval and dose adjustment.
- Both medicines lower blood pressure, so the combination may cause dizziness; start with the lowest vardenafil dose.
- Always declare felodipine and all other medicines during your ED consultation for a safe, personalised assessment.
- Watch for dizziness or fainting when standing up; seek help if symptoms are severe or persistent.
- This interaction is manageable, unlike the dangerous combination with nitrates which must never be taken together.
What Your Prescriber Will Check Before Prescribing Vardenafil and Felodipine Together
When you request vardenafil through Cured Pharmacy's online consultation, the UK-registered prescriber will ask detailed questions about your current medicines, including felodipine. They will check that your blood pressure is stable and well controlled, as uncontrolled high blood pressure or very low blood pressure can make ED treatment unsuitable.
The prescriber will also review your cardiovascular health more broadly. They will ask about any history of heart attack, stroke, angina, heart failure or other heart conditions, because these can affect whether sexual activity—and therefore ED treatment—is safe for you [2]. If you have recently had a heart attack or stroke, or if you have unstable angina or severe heart failure, ED medicines may not be appropriate.
If the prescriber decides that vardenafil is suitable for you, they may recommend starting with a lower dose (such as 5mg) to minimise the risk of low blood pressure. They will also advise you on what symptoms to watch for and when to seek medical help. This individualised approach ensures that treatment is both effective and safe.
Declaring All Your Medicines
It is essential to list every medicine you take during the consultation, including prescription medicines, over-the-counter products, herbal remedies and supplements. Some medicines can interact with vardenafil in ways that are not immediately obvious, and your prescriber needs the full picture to make a safe decision. Never stop or change a prescribed medicine without speaking to your doctor or pharmacist first.
Practical Advice for Taking Vardenafil and Felodipine Safely
If your prescriber approves the combination of vardenafil and felodipine, there are several practical steps you can take to use the medicines safely. First, take vardenafil exactly as prescribed—do not take more than one dose in 24 hours, and do not exceed the recommended dose. Taking more will not improve the effect but will increase the risk of side effects, including low blood pressure.
Be cautious when standing up from sitting or lying down, especially after taking vardenafil, as this is when you are most likely to feel dizzy if your blood pressure drops. Avoid drinking large amounts of alcohol, as this can worsen erectile dysfunction and add to the blood-pressure-lowering effect of both medicines. Grapefruit juice can also raise vardenafil levels in the blood, so it is best avoided.
If you experience persistent dizziness, light-headedness, fainting or any chest pain during sexual activity, stop and seek medical advice. These symptoms may indicate that your blood pressure has dropped too low or that there is another issue that needs attention. Always keep your GP informed about all the medicines you are taking, including those obtained through online pharmacies.
When to get urgent help
- An erection lasting more than 4 hours (priapism)—go to A&E immediately to prevent permanent damage
- Sudden loss of vision in one or both eyes—stop vardenafil and seek urgent medical help
- Sudden decrease or loss of hearing, possibly with ringing in the ears or dizziness—seek medical advice promptly
- Chest pain during or after sexual activity—stop and call 999; do not take nitrate medicines
- Severe dizziness, fainting or feeling very unwell after taking vardenafil—seek same-day medical advice
Call 999 or go to A&E in an emergency, or contact NHS 111 for urgent advice.
Alternative ED Treatments If Vardenafil and Felodipine Are Not Suitable Together
In most cases, vardenafil and felodipine can be used together safely with appropriate dose adjustment and monitoring. However, if your prescriber has concerns about this combination—for example, if your blood pressure is difficult to control or you have other complicating health conditions—they may suggest an alternative ED treatment.
Other PDE5 inhibitors, such as sildenafil (Viagra) or tadalafil (Cialis), work in similar ways to vardenafil and have comparable interactions with calcium channel blockers [3][4]. The choice between them often comes down to how quickly you want the medicine to work and how long you want the effect to last. Tadalafil, for example, can last up to 36 hours, while sildenafil and vardenafil have shorter durations.
If oral ED medicines are not suitable, your doctor may discuss other options such as Vitaros (alprostadil cream) or Caverject (alprostadil injection), which work locally rather than affecting blood pressure throughout the body [7]. Eroxon, a topical gel medical device, is another option available without prescription. Your GP or a specialist can help you find the treatment that best fits your individual circumstances.
When to See Your GP
If you are experiencing erectile dysfunction for the first time, it is important to see your GP for a full assessment. ED can be an early warning sign of underlying health conditions such as heart disease, diabetes or high cholesterol [1][2]. Treating the underlying cause, as well as the ED itself, can improve your overall health and quality of life. Your GP can also review all your medicines and refer you to a specialist if needed.
Scientific References
- NHS. (n.d.). Erectile dysfunction (impotence). NHS website. https://www.nhs.uk/conditions/erection-problems-erectile-dysfunction/ [accessed 30 October 2026]
- National Institute for Health and Care Excellence. (n.d.). Erectile dysfunction. Clinical Knowledge Summaries. https://cks.nice.org.uk/topics/erectile-dysfunction/ [accessed 30 October 2026]
- Joint Formulary Committee. (n.d.). Sildenafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/sildenafil/ [accessed 30 October 2026]
- Joint Formulary Committee. (n.d.). Tadalafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/tadalafil/ [accessed 30 October 2026]
- Joint Formulary Committee. (n.d.). Vardenafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/vardenafil/ [accessed 30 October 2026]
- Joint Formulary Committee. (n.d.). Alprostadil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/alprostadil/ [accessed 30 October 2026]
Information on this page is for educational purposes only and is not medical advice. Prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting or changing any medication.
Your Questions Answered
Can I take vardenafil if I am on felodipine for high blood pressure?
Yes, in most cases vardenafil can be taken with felodipine, provided your blood pressure is stable and your prescriber has reviewed your full medical history. They may recommend a lower starting dose of vardenafil to minimise the risk of low blood pressure.
Will vardenafil and felodipine together cause my blood pressure to drop dangerously?
The combination can lower blood pressure more than either medicine alone, but this is usually manageable with careful prescribing and monitoring. Dangerous drops are rare when the medicines are used as directed, unlike the life-threatening interaction with nitrates.
What symptoms should I watch for when taking vardenafil and felodipine together?
Watch for dizziness, light-headedness, fainting or feeling unsteady when you stand up. If you experience persistent symptoms, chest pain during sex, or any sudden vision or hearing loss, seek medical help immediately.
Do I need to tell my GP that I am taking vardenafil with felodipine?
Yes, it is important to keep your GP informed about all the medicines you are taking, including those obtained through online pharmacies. This helps ensure your overall treatment is coordinated and safe.
Can I take vardenafil with other calcium channel blockers like amlodipine?
Yes, the interaction between vardenafil and other calcium channel blockers (such as amlodipine, nifedipine or diltiazem) is similar to that with felodipine. Your prescriber will assess your individual situation and advise on the safest approach.
Is it safe to drink alcohol when taking vardenafil and felodipine?
Drinking large amounts of alcohol can worsen erectile dysfunction and add to the blood-pressure-lowering effects of both medicines, increasing the risk of dizziness. It is best to limit alcohol intake when using these medicines together.
What should I do if I feel dizzy after taking vardenafil with felodipine?
Sit or lie down until the dizziness passes, and avoid standing up quickly. If dizziness is severe, persistent or accompanied by chest pain or fainting, seek medical help immediately.
Are there any ED treatments that do not interact with felodipine?
All PDE5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil) have similar interactions with blood-pressure medicines. If oral ED medicines are not suitable, your doctor may discuss alternatives such as alprostadil cream or injection, which work locally and have different side-effect profiles.
Get Discreet ED Treatment Online
Reviewed by UK-based prescribers · Takes under 3 minutes · Discreet Packaging
Medically reviewed by
Tarun Kumar, Superintendent Pharmacist (GPhC 2233073)