Mounjaro vs Wegovy UK - Compare Prices & Cheapest Option

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Mounjaro vs Wegovy - Compare Prices & Cheapest Option UK

Compare Mounjaro vs Wegovy at the cheapest UK price — get £20 off your first order with code Weightlossnew.

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Treatment from £145.00

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Woman using Cured Pharmacy online consultation for weight loss treatment

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LIVE PRICING

Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Mounjaro vs Wegovy: Clinical Comparison and UK Switching Guide

When comparing mounjaro vs wegovy, UK patients often ask which medication delivers superior weight loss outcomes and better value. Both are GLP-1 receptor agonists licensed by the MHRA for chronic weight management, but Mounjaro (tirzepatide) also activates GIP receptors, offering a dual-action mechanism that clinical trials suggest may produce greater average weight reduction. This guide examines the evidence, pricing, and practical considerations for patients considering switching from Wegovy to Mounjaro or choosing between them for the first time.

How Mounjaro vs Wegovy Mechanisms Differ

The fundamental difference in the mounjaro vs wegovy comparison lies in their receptor activity. Wegovy (semaglutide) is a selective GLP-1 receptor agonist that mimics the incretin hormone GLP-1, suppressing appetite and slowing gastric emptying [1]. Mounjaro (tirzepatide) is a dual GIP/GLP-1 receptor agonist, activating both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors simultaneously [2]. This dual mechanism appears to enhance insulin secretion, improve insulin sensitivity, and promote greater fat metabolism compared to GLP-1 action alone.

In our clinical experience at Cured Pharmacy, patients switching from Wegovy to Mounjaro often report enhanced satiety and more consistent appetite suppression during the maintenance phase. The GIP component may also influence fat storage pathways in adipose tissue, though research into these metabolic effects is ongoing [2]. Both medications require subcutaneous injection once weekly, and both are subject to prescriber approval following online clinical assessment by our UK-registered team.

Mounjaro vs Wegovy Weight Loss Results: Clinical Trial Data

Head-to-head clinical evidence strongly favours Mounjaro in the mounjaro vs wegovy weight loss comparison. The SURPASS-2 trial directly compared tirzepatide to semaglutide 1mg in adults with type 2 diabetes, demonstrating that tirzepatide 15mg produced an average weight loss of 11.2kg versus 5.7kg with semaglutide over 40 weeks [3]. Whilst this trial used the diabetes formulation of semaglutide rather than the higher 2.4mg Wegovy dose, subsequent real-world data suggests the weight loss advantage persists.

In the SURMOUNT-1 trial, adults without diabetes receiving Mounjaro 15mg achieved an average body weight reduction of 20.9% over 72 weeks, compared to 14.9% in the STEP 1 trial of Wegovy 2.4mg [1][3]. Approximately 57% of Mounjaro participants lost at least 20% of their baseline weight, versus 35% on Wegovy [3]. These are average trial results—individual outcomes vary based on adherence, lifestyle factors, and metabolic response. Both medications require commitment to dietary modification and increased physical activity for optimal results.

Time to Plateau and Maintenance

When evaluating mounjaro vs wegovy for long-term use, both medications typically reach peak weight loss between 60-72 weeks of continuous treatment [1][3]. Patients switching from Wegovy to Mounjaro after reaching a plateau on semaglutide may experience additional weight reduction during the titration to higher tirzepatide doses, though this should be discussed with a prescriber. Discontinuation of either medication often results in gradual weight regain, making ongoing treatment necessary for sustained benefit in most individuals.

Mounjaro vs Wegovy Side Effects and Tolerability

The side effect profiles in the mounjaro vs wegovy comparison are broadly similar, as both medications slow gastric emptying and modulate gut hormone signalling. The most common adverse effects include nausea, diarrhoea, constipation, vomiting, and abdominal discomfort, typically most pronounced during dose escalation [1][2]. In clinical trials, approximately 10-20% of participants on either medication experienced nausea, though severe cases leading to discontinuation were uncommon.

Our superintendent pharmacist, Tarun Kumar (GPhC 2233073), notes that individual tolerability varies considerably—some patients switching from Wegovy to Mounjaro report improved gastrointestinal tolerance on tirzepatide, whilst others find semaglutide gentler. Starting at the lowest dose and following the recommended titration schedule minimises side effects for both medications. Rare but serious risks include pancreatitis, gallbladder disease, and thyroid C-cell tumours (observed in rodent studies), making thorough prescriber assessment essential before starting either treatment [1][2].

Managing Gastrointestinal Symptoms

Whether choosing Mounjaro or Wegovy, patients can reduce nausea and digestive upset by eating smaller, more frequent meals, avoiding high-fat foods immediately after injection, and staying well-hydrated. Injecting at a consistent time each week and rotating injection sites (abdomen, thigh, upper arm) may also improve comfort. If side effects become intolerable, a prescriber may recommend slowing the dose escalation rather than discontinuing treatment entirely.

Treatment Active Ingredient Weekly Dose Range Starting Price (4 weeks)
Mounjaro Tirzepatide (GIP/GLP-1) 2.5mg - 15mg From £145.00
Wegovy Injection Semaglutide (GLP-1) 0.25mg - 2.4mg From £89.00
Wegovy Oral Tablet Semaglutide (GLP-1) Daily 3mg - 14mg From £83.00

Mounjaro vs Wegovy UK Pricing and Cost Comparison

UK pricing is a critical factor in the mounjaro vs wegovy decision. At Cured Pharmacy, Mounjaro is priced from £124.99 per four-week supply, whilst Wegovy starts from £124.99 for equivalent monthly treatment [4]. Patients can Save £20 off their first order using code Weightlossnew, making the initial month of Mounjaro £124.99 and Wegovy £124.99. These are the cheapest UK prices available through our GPhC-registered pharmacy (9012511), with transparent pricing shown before completing the online consultation.

Whilst Mounjaro carries a higher upfront cost, some patients find the enhanced weight loss outcomes justify the price difference when calculated per kilogram lost. The comparison table below shows dosing schedules and costs for both treatments. All purchases require clinical assessment by a UK prescriber, and prices include the medication, prescriber review, and discreet next-day delivery across the UK.

Switching from Wegovy to Mounjaro: Practical Guidance

Patients considering switching from Wegovy to Mounjaro should consult a prescriber to determine the appropriate starting dose of tirzepatide based on their current semaglutide dose and treatment response. MHRA guidance does not specify a direct dose conversion, but clinical practice typically suggests starting Mounjaro at 2.5mg weekly regardless of prior Wegovy dose, then titrating upward every four weeks as tolerated [2]. This approach minimises gastrointestinal side effects during the transition.

When switching between these mounjaro vs wegovy options, there is no required washout period—patients can begin Mounjaro the week following their final Wegovy injection. However, overlapping doses is not recommended due to additive GLP-1 effects and increased risk of nausea and hypoglycaemia. Our clinical team at Cured Pharmacy provides individualised switching protocols during the online consultation, ensuring safe transition under UK prescriber supervision. Patients should monitor for changes in blood glucose if diabetic, and report persistent side effects promptly.

Eligibility and Contraindications

Both Mounjaro and Wegovy are licensed in the UK for adults with a BMI of 30 kg/m² or greater, or 27 kg/m² with at least one weight-related comorbidity such as hypertension or type 2 diabetes [1][2]. Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, and severe gastrointestinal disease. Pregnancy and breastfeeding are also contraindications—patients should use effective contraception during treatment and discontinue at least two months before planned conception.

Mounjaro vs Wegovy: Which Should You Choose?

The mounjaro vs wegovy choice ultimately depends on individual weight loss goals, budget, and tolerability. Mounjaro offers statistically superior average weight loss in clinical trials, making it the preferred option for patients seeking maximum reduction and willing to invest in the higher cost [3]. Wegovy remains highly effective, more affordable, and may suit those prioritising cost-effectiveness or who have responded well to GLP-1 monotherapy.

At Cured Pharmacy, our UK-registered prescribers assess each patient's medical history, current medications, weight loss targets, and financial considerations during the free online consultation (under three minutes). We supply only genuine UK-licensed Mounjaro and Wegovy, with discreet packaging and next-day delivery as standard. Patients can start their assessment at any time via our secure platform, with same-day prescriber review available Monday to Friday. For personalised guidance on the mounjaro vs wegovy decision, contact our team on (+44) 116 4646009 or begin your clinical assessment online today.

Scientific References

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  2. Medicines and Healthcare products Regulatory Agency. (2023). Mounjaro 2.5 mg solution for injection in pre-filled pen: Summary of Product Characteristics. MHRA. [accessed 15 August 2026]
  3. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. [accessed 15 August 2026]
  4. Cured Pharmacy. (2025). Weight loss treatment pricing and availability. Cured Pharmacy Ltd (GPhC 9012511). [accessed 15 August 2026]
  5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

Trusted by thousands

Real people, real results

Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Is Mounjaro better than Wegovy for weight loss?
Clinical trial data suggests Mounjaro produces greater average weight loss than Wegovy—20.9% versus 14.9% over 72 weeks in respective trials. Individual results vary, and both medications require prescriber approval and lifestyle modification for optimal outcomes.
Can I switch from Wegovy to Mounjaro in the UK?
Yes, patients can switch from Wegovy to Mounjaro under prescriber supervision. The transition typically begins with Mounjaro 2.5mg weekly, regardless of prior Wegovy dose, with no washout period required between medications.
What is the price difference between Mounjaro vs Wegovy at Cured Pharmacy?
Mounjaro costs from £124.99 per four weeks, whilst Wegovy injection starts at £124.99 and Wegovy oral tablets from £124.99. All prices include prescriber consultation and next-day UK delivery, with £20 off first orders using code Weightlossnew.
Do Mounjaro and Wegovy have the same side effects?
Both medications share similar gastrointestinal side effects including nausea, diarrhoea, and constipation, most common during dose escalation. Individual tolerability varies—some patients find one medication better tolerated than the other.
How long does it take to see results with Mounjaro vs Wegovy?
Most patients notice appetite suppression within the first two weeks on either medication, with measurable weight loss typically evident by week four. Peak weight reduction occurs around 60-72 weeks of continuous treatment for both Mounjaro and Wegovy.
Which is more effective: Mounjaro or Wegovy?
In the mounjaro vs wegovy comparison, Mounjaro demonstrated superior average weight loss in clinical trials due to its dual GIP/GLP-1 mechanism. Wegovy remains highly effective, and the best choice depends on individual response, budget, and prescriber recommendation.
Can I use Mounjaro and Wegovy together?
No, combining Mounjaro and Wegovy is not recommended due to overlapping GLP-1 receptor activity, which increases the risk of severe nausea, vomiting, and hypoglycaemia. Patients should use one medication at a time under prescriber supervision.
Is Mounjaro available on the NHS like Wegovy?
Wegovy is available via NHS prescription in England under specific NICE criteria (BMI ≥35 with comorbidities, or BMI ≥30 in certain cases). Mounjaro is not yet routinely commissioned by the NHS for weight management, making private prescription the primary UK access route at present.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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