Mounjaro vs Wegovy UK - Compare Prices & Cheapest Option

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Cheapest Mounjaro vs Wegovy UK - Compare Prices

Compare Mounjaro and Wegovy at the cheapest UK prices — Save £20 off your first order with code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Mounjaro vs Wegovy: Which Weight Loss Injection Is Right for You?

Choosing between Mounjaro vs Wegovy can feel overwhelming when both injections promise significant weight loss results. As a UK-registered pharmacy serving thousands of patients, we've helped countless individuals navigate this decision based on clinical evidence, pricing, and individual health profiles. This comprehensive comparison draws on the latest SURPASS and STEP trial data to help you make an informed choice with guidance from our superintendent pharmacist, Tarun Kumar GPhC 2233073.

How Mounjaro vs Wegovy Work Differently in Your Body

The fundamental difference between Mounjaro vs Wegovy lies in their mechanism of action. Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist that targets two hormonal pathways simultaneously to regulate appetite and blood sugar [1]. Wegovy contains semaglutide, a GLP-1 receptor agonist that works on a single pathway but has been clinically proven effective since 2021 [2].

In clinical practice, this dual-action mechanism means Mounjaro may produce more pronounced effects on appetite suppression and metabolic regulation for some patients. The SURPASS-2 trial demonstrated that tirzepatide led to average weight reductions of up to 12.4kg at the highest dose over 40 weeks [1]. Meanwhile, the STEP 1 trial showed semaglutide 2.4mg achieved average weight loss of 14.9% body weight over 68 weeks [2]. Both medications slow gastric emptying, reduce hunger signals, and improve glycaemic control, making them effective tools when combined with lifestyle modifications.

Your body's response to either medication depends on individual factors including baseline BMI, metabolic health, and adherence to the dosing schedule. Both require subcutaneous injection once weekly and gradual dose escalation to minimise gastrointestinal side effects. All prescriptions are subject to clinical assessment by our UK-registered prescribers to ensure suitability and safety.

Mounjaro vs Wegovy Weight Loss Results: What Clinical Trials Show

When comparing Mounjaro vs Wegovy for weight loss outcomes, both medications demonstrate impressive results in peer-reviewed trials. The SURMOUNT-1 trial evaluated tirzepatide specifically for weight management in adults without diabetes, showing average weight reductions of 15.0% with the 5mg dose, 19.5% with 10mg, and 20.9% with 15mg over 72 weeks [3]. These results positioned Mounjaro as one of the most effective pharmacological interventions for obesity currently available in the UK.

Wegovy's efficacy is equally well-documented across the STEP trial programme. STEP 1 enrolled 1,961 adults with obesity or overweight plus weight-related comorbidities, demonstrating that 2.4mg semaglutide produced 14.9% average body weight reduction compared to 2.4% with placebo over 68 weeks [2]. Approximately 50% of participants achieved at least 15% weight loss, a threshold associated with significant cardiometabolic benefits. Both medications require ongoing treatment, as discontinuation typically results in weight regain.

In our clinical experience at Cured Pharmacy, patient responses vary considerably. Some individuals respond exceptionally well to Wegovy's established semaglutide formulation, whilst others achieve better results with Mounjaro's dual-action mechanism. The choice between Mounjaro vs Wegovy should be guided by your prescriber's assessment of your medical history, weight loss goals, and tolerance to side effects during the titration phase.

Head-to-Head Comparison: SURPASS-2 Direct Evidence

The SURPASS-2 trial provides the only direct head-to-head comparison of tirzepatide against semaglutide, though it was conducted in patients with type 2 diabetes rather than weight management specifically [1]. At 40 weeks, tirzepatide 15mg produced significantly greater HbA1c reduction and weight loss compared to semaglutide 1mg. However, this comparison used the diabetes dose of semaglutide, not the 2.4mg weight loss dose found in Wegovy, limiting direct applicability to the Mounjaro vs Wegovy decision for obesity treatment. Ongoing trials comparing the medications at their respective weight management doses will provide clearer guidance for UK patients in the coming years.

Side Effects: Mounjaro vs Wegovy Safety Profiles

The safety profiles of Mounjaro vs Wegovy share considerable overlap, as both belong to the incretin mimetic class and produce similar gastrointestinal effects. The most commonly reported side effects include nausea, diarrhoea, vomiting, constipation, and abdominal discomfort, typically most pronounced during dose escalation [1][2]. In clinical trials, these effects were generally mild to moderate and diminished over time as patients adapted to treatment.

Nausea occurred in approximately 44% of Mounjaro users and 44% of Wegovy users in their respective trials, though severity and duration varied individually [3][4]. Our clinical team advises patients to eat smaller meals, avoid high-fat foods, and stay well-hydrated to manage these symptoms. Serious adverse events are rare but include pancreatitis, gallbladder disease, and hypoglycaemia when combined with insulin or sulphonylureas. Both medications carry a boxed warning regarding thyroid C-cell tumours observed in rodent studies, though human relevance remains unclear.

When comparing Mounjaro vs Wegovy for tolerability, discontinuation rates due to adverse events were similar in trials, ranging from 4-7% across doses [3][4]. Individual tolerance varies significantly, and some patients who cannot tolerate one medication may respond better to the other. All potential side effects are discussed during your clinical assessment, and our pharmacist team remains available throughout treatment to address concerns and optimise your experience.

Managing Side Effects During Titration

Both Mounjaro and Wegovy require gradual dose escalation over several months to reach therapeutic levels whilst minimising gastrointestinal upset. Mounjaro starts at 2.5mg weekly for four weeks, increasing to 5mg, then optionally to 7.5mg, 10mg, 12.5mg, and 15mg at four-week intervals. Wegovy begins at 0.25mg weekly, escalating monthly through 0.5mg, 1mg, 1.7mg, to the maintenance dose of 2.4mg. Patients who experience persistent side effects can remain at a lower dose or slow the escalation schedule under prescriber guidance. This flexible approach helps optimise the balance between efficacy and tolerability for each individual.

Feature Mounjaro Wegovy
Active Ingredient Tirzepatide Semaglutide
Mechanism Dual GIP/GLP-1 agonist GLP-1 agonist
Average Weight Loss Up to 20.9% (72 weeks) Up to 14.9% (68 weeks)
Starting Dose 2.5mg weekly 0.25mg weekly
Maintenance Dose 5-15mg weekly 2.4mg weekly
Price at Cured Pharmacy From £145.00/month From £89.00/month
Injection Frequency Once weekly Once weekly
Common Side Effects Nausea, diarrhoea, vomiting Nausea, diarrhoea, vomiting
UK Regulatory Status MHRA licensed MHRA licensed

Mounjaro vs Wegovy UK Pricing and Value Comparison

Cost is a significant consideration when choosing between Mounjaro vs Wegovy, as neither is currently funded by the NHS for weight management in most areas, requiring private prescription. At Cured Pharmacy, transparent pricing ensures you know exactly what to expect before completing your clinical assessment. Mounjaro is available from £124.99 per month, whilst Wegovy starts from £124.99 per month, both representing competitive UK pricing with our lowest price guarantee.

The price difference reflects several factors including manufacturing costs, market positioning, and dose escalation schedules. Wegovy's longer market presence in the UK weight loss sector has enabled more competitive pricing, whilst Mounjaro's dual-action mechanism and recent launch command a premium. However, cost-effectiveness should be evaluated based on your individual response, as superior weight loss outcomes with one medication may justify higher monthly expenditure over your treatment journey.

Cured Pharmacy offers £20 off your first order with code Weightlossnew, reducing initial treatment costs whilst you assess tolerability and efficacy. Both medications require ongoing monthly prescriptions following successful clinical assessment by our UK-registered prescribers. We provide upfront pricing with no hidden fees, free online consultations completed in under three minutes, and discreet next-day delivery across the UK. Our superintendent pharmacist Tarun Kumar oversees all clinical protocols to ensure you receive genuine, MHRA-licensed medications with full regulatory compliance.

Who Should Choose Mounjaro vs Wegovy: Clinical Guidance

The decision between Mounjaro vs Wegovy depends on individual clinical circumstances, treatment history, and weight loss goals. Wegovy may be particularly suitable for patients who prefer a medication with extensive long-term safety data, as semaglutide has been used for diabetes management since 2017 and weight management since 2021 [2]. Its established track record provides reassurance for both patients and prescribers, especially for individuals with cardiovascular risk factors who may benefit from semaglutide's demonstrated cardioprotective effects.

Mounjaro represents an excellent option for patients seeking maximum weight loss potential or those who have not achieved adequate results with GLP-1 agonists alone. The dual GIP/GLP-1 mechanism may offer advantages for individuals with significant insulin resistance or metabolic syndrome [1]. Additionally, patients who experienced intolerable side effects with Wegovy sometimes find better tolerability with Mounjaro despite the medications' similar profiles, likely due to individual pharmacological sensitivities.

Both Mounjaro vs Wegovy require prescription following clinical assessment of your BMI, weight-related comorbidities, previous weight loss attempts, and contraindications. NICE guidelines recommend pharmacological intervention for adults with BMI ≥30 kg/m², or ≥27 kg/m² with weight-related complications such as type 2 diabetes, hypertension, or sleep apnoea [5]. Our prescribers evaluate your complete medical history during the online consultation to determine which medication, if any, is appropriate and safe for your circumstances.

Contraindications and Precautions

Neither Mounjaro nor Wegovy should be used during pregnancy or breastfeeding, in patients with personal or family history of medullary thyroid carcinoma, or those with multiple endocrine neoplasia syndrome type 2. Caution is required in patients with severe gastrointestinal disease, history of pancreatitis, or diabetic retinopathy. Both medications can interact with oral contraceptives and other medications due to delayed gastric emptying. Your prescriber will review all current medications and health conditions during assessment to ensure safe prescribing. Patients must be willing to engage with lifestyle modifications including dietary changes and increased physical activity for optimal outcomes.

Getting Started with Mounjaro vs Wegovy at Cured Pharmacy

Beginning your weight loss journey with either Mounjaro vs Wegovy through Cured Pharmacy follows a straightforward, fully regulated process designed to ensure safety and convenience. Start by completing our free online clinical assessment, which takes under three minutes and covers your medical history, current medications, weight loss goals, and any contraindications. Our UK-registered prescribers review every submission individually, typically within 24 hours, to determine suitability and issue a prescription if clinically appropriate.

Once approved, your chosen medication is dispensed by our GPhC-registered pharmacy (registration 9012511) and dispatched via next-day delivery in 100% discreet packaging. Each delivery includes comprehensive patient information leaflets, injection technique guidance, and access to our pharmacist support team for any questions throughout treatment. We recommend starting injections on the same day each week, rotating injection sites between abdomen, thigh, and upper arm to minimise injection site reactions.

Ongoing treatment requires monthly prescription renewals following brief clinical check-ins to monitor progress, side effects, and dose adjustments. Our transparent pricing model means you pay the same competitive rate whether choosing Mounjaro vs Wegovy, with no hidden consultation fees or subscription charges. Both medications are genuine UK-licensed products sourced directly from licensed wholesalers, never grey-market imports. For any clinical concerns during treatment, our superintendent pharmacist Tarun Kumar GPhC 2233073 and prescriber team remain available to optimise your treatment pathway and ensure safe, effective weight management outcomes.

What to Expect in Your First Month

During your first month on either Mounjaro or Wegovy, expect to experience the titration phase with the lowest starting dose. Most patients notice reduced appetite and early satiety within the first week, though significant weight loss typically begins from week 4-6 onwards. Mild nausea and gastrointestinal changes are common initially but usually resolve as your body adapts. Keep a symptom diary to discuss with your prescriber at your first monthly review. Weigh yourself weekly at the same time of day, and take progress photos and measurements beyond just scale weight, as body composition changes may precede numerical weight loss. Commit to sustainable dietary modifications and regular physical activity to maximise results from whichever medication you and your prescriber select.

Scientific References

  1. Frías, J. P., Davies, M. J., Rosenstock, J., et al. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. New England Journal of Medicine, 385(6), 503-515. [accessed 15 August 2026]
  2. Wilding, J. P., Batterham, R. L., Calanna, S., et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  3. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. [accessed 15 August 2026]
  4. Rubino, D., Abrahamsson, N., Davies, M., et al. (2021). Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity. JAMA, 325(14), 1414-1425. [accessed 15 August 2026]
  5. National Institute for Health and Care Excellence. (2023). Obesity: identification, assessment and management (CG189). [accessed 15 August 2026]
  6. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  7. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  8. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Which is better for weight loss, Mounjaro vs Wegovy?
Mounjaro demonstrated slightly higher average weight loss in clinical trials (up to 20.9% vs 14.9%), but individual responses vary significantly. Your prescriber will recommend the most suitable option based on your medical history, treatment goals, and tolerance.
Can I switch from Wegovy to Mounjaro or vice versa?
Yes, switching between Mounjaro vs Wegovy is possible under prescriber guidance. A washout period is not required, but dose adjustment and monitoring are necessary to manage the transition safely and effectively.
Is Mounjaro vs Wegovy cheaper in the UK?
Wegovy is more affordable at Cured Pharmacy, starting from £124.99 per month compared to Mounjaro from £124.99. Both represent competitive UK pricing with our lowest price guarantee and £20 off your first order with code Weightlossnew.
Do Mounjaro and Wegovy have the same side effects?
Both Mounjaro vs Wegovy share similar side effect profiles, predominantly gastrointestinal symptoms like nausea, diarrhoea, and vomiting during dose escalation. Individual tolerance varies, and some patients find one medication more tolerable than the other.
How quickly does Mounjaro vs Wegovy work?
Most patients notice appetite suppression within the first week of either medication, with measurable weight loss typically beginning from week 4-6. Maximum efficacy is usually achieved after several months at the maintenance dose with consistent adherence.
Can I get Mounjaro or Wegovy on the NHS?
NHS availability for Mounjaro vs Wegovy for weight management is extremely limited and varies by region. Most patients access these medications privately through registered pharmacies like Cured Pharmacy following clinical assessment by UK prescribers.
Do I need to inject Mounjaro and Wegovy in the same way?
Yes, both Mounjaro vs Wegovy are administered as once-weekly subcutaneous injections using pre-filled pens. Injection sites include the abdomen, thigh, or upper arm, rotated weekly to minimise irritation. Full technique guidance is provided with your first prescription.
What happens if I stop taking Mounjaro or Wegovy?
Discontinuing either Mounjaro vs Wegovy typically results in gradual weight regain as the appetite-suppressing effects diminish. Both medications are intended for long-term use alongside sustained lifestyle modifications to maintain weight loss outcomes achieved during treatment.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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