Mounjaro vs Wegovy UK - Compare Prices & Cheapest Option

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Cheapest Mounjaro vs Wegovy UK - Compare Prices

Compare Mounjaro vs Wegovy at the cheapest UK price from £124.99 — Save £20 off with code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Mounjaro vs Wegovy UK: Which Weight Loss Injection Is Right for You?

When comparing mounjaro vs wegovy uk options, both prescription weight loss injections have transformed obesity treatment, but they work differently and deliver distinct results. Mounjaro (tirzepatide) targets two hormones for appetite control, whilst Wegovy (semaglutide) acts on one — a difference that translates into measurably different weight loss outcomes in clinical trials. Understanding which treatment aligns with your health profile, budget, and weight loss goals requires examining the evidence behind each medication, and that's precisely what this pharmacist-led comparison will help you do.

How Mounjaro vs Wegovy UK Medications Work Differently

The fundamental difference between mounjaro vs wegovy uk treatments lies in their mechanism of action. Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics a single gut hormone to reduce appetite and slow gastric emptying [1]. Mounjaro, however, is a dual agonist — it activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, offering a two-pronged approach to metabolic regulation [2].

This dual action means Mounjaro influences insulin secretion, fat metabolism, and energy expenditure more comprehensively than Wegovy. In our clinical experience at Cured Pharmacy, patients often ask whether this translates to better results — and the trial data suggests it does. The SURPASS-2 head-to-head trial directly compared tirzepatide against semaglutide, showing tirzepatide delivered superior weight loss across all doses [2]. However, both medications require gradual dose escalation and work best alongside dietary modification and increased physical activity.

Receptor Targeting: Single vs Dual Agonism

Wegovy's single-receptor approach has proven highly effective — average weight loss in the STEP trials reached 15% of body weight over 68 weeks [1]. Mounjaro's dual-receptor activation, however, achieved up to 22.5% average weight reduction in SURMOUNT trials at the highest dose [2]. Both medications are administered as weekly subcutaneous injections and require ongoing prescriber supervision. At Cured Pharmacy, every prescription follows a comprehensive clinical assessment by our UK-registered prescribers to ensure suitability and safety.

Mounjaro vs Wegovy UK Clinical Trial Results Compared

When evaluating mounjaro vs wegovy uk efficacy, the SURPASS-2 trial provides the gold standard comparison. This 40-week study enrolled 1,879 adults with type 2 diabetes, comparing tirzepatide (5mg, 10mg, and 15mg) directly against semaglutide 1mg [2]. Results showed tirzepatide 15mg achieved an average 5.5kg greater weight loss than semaglutide — a statistically significant and clinically meaningful difference.

For weight management specifically, the SURMOUNT-1 trial demonstrated Mounjaro's potential in adults without diabetes. Participants taking tirzepatide 15mg lost an average of 22.5% body weight over 72 weeks, compared to 2.4% with placebo [3]. Wegovy's STEP 1 trial showed 14.9% average weight loss over 68 weeks versus 2.4% placebo [1]. Both represent substantial improvements over lifestyle modification alone, but the numerical advantage consistently favours tirzepatide in head-to-head and parallel comparisons.

Side Effects: Mounjaro vs Wegovy UK Patient Experiences

The side effect profiles of mounjaro vs wegovy uk treatments overlap considerably, as both are incretin-based therapies affecting gastrointestinal function. The most common adverse effects include nausea, diarrhoea, vomiting, constipation, and abdominal discomfort [1][2]. These typically emerge during dose escalation and diminish over time as the body adapts.

In SURPASS-2, gastrointestinal side effects occurred in 70-80% of tirzepatide participants versus 60-65% with semaglutide, though discontinuation rates remained similar (4-7% across groups) [2]. Importantly, both medications carry a boxed warning regarding thyroid C-cell tumours observed in rodent studies, though no causal link has been established in humans. Our superintendent pharmacist Tarun Kumar emphasises the importance of reporting any persistent neck swelling, hoarseness, or difficulty swallowing during treatment. Both medications are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.

Managing Gastrointestinal Symptoms

Most patients find gastrointestinal side effects manageable with simple strategies: eating smaller, more frequent meals, avoiding high-fat foods, and staying well-hydrated. The gradual dose titration schedule built into both mounjaro vs wegovy uk treatment protocols helps minimise these effects. At Cured Pharmacy, our clinical team provides ongoing support throughout your treatment journey, with advice tailored to your individual response and any side effects you experience.

Feature Mounjaro (Tirzepatide) Wegovy (Semaglutide)
Active Ingredient Tirzepatide Semaglutide
Mechanism Dual GLP-1/GIP agonist GLP-1 agonist
Dosing Frequency Weekly injection Weekly injection
Starting Dose 2.5mg weekly 0.25mg weekly
Maximum Dose 15mg weekly 2.4mg weekly
Average Weight Loss Up to 22.5% (72 weeks) Up to 14.9% (68 weeks)
Common Side Effects Nausea, diarrhoea, vomiting Nausea, diarrhoea, vomiting
Starting Price (Cured) From £145.00 From £89.00
Prescription Required Yes - UK prescriber Yes - UK prescriber

Dosing Schedules: Mounjaro vs Wegovy UK Titration Protocols

Understanding the dosing progression for mounjaro vs wegovy uk treatments is essential for setting realistic expectations. Wegovy begins at 0.25mg weekly for four weeks, then escalates monthly through 0.5mg, 1mg, and 1.7mg, reaching the maintenance dose of 2.4mg by week 17 [1]. This gradual increase allows your body to adapt whilst minimising gastrointestinal side effects.

Mounjaro follows a similar philosophy but with different increments: starting at 2.5mg weekly for four weeks, then increasing every four weeks through 5mg, 7.5mg, 10mg, 12.5mg, to a maximum of 15mg [2]. The higher absolute doses reflect tirzepatide's different receptor binding characteristics — not greater potency per milligram. Both medications are administered via pre-filled injection pens designed for self-administration in the abdomen, thigh, or upper arm. Our clinical team at Cured Pharmacy provides detailed injection technique guidance and ongoing monitoring throughout your dose escalation, ensuring you feel confident and supported at every stage.

Cost Analysis: Mounjaro vs Wegovy UK Pricing at Cured Pharmacy

Price is a significant consideration when comparing mounjaro vs wegovy uk options, as both are premium weight management treatments. At Cured Pharmacy, we guarantee the lowest UK prices with complete transparency — you'll see exact costs before completing your clinical assessment. Wegovy starts from £124.99, whilst Mounjaro begins at £124.99, reflecting differences in manufacturing, licensing, and market positioning.

New patients can access an additional £20 discount on their first order using code Weightlossnew, making these clinically proven treatments more accessible. Unlike some providers, we never hide prices behind consultations or charge separate prescriber fees — what you see is what you pay, including your medication, clinical assessment by a UK-registered prescriber, and discreet home delivery. Both treatments represent a significant investment in your health, but when you consider the clinical trial data showing sustained, substantial weight loss, many patients find the cost justifiable as part of a comprehensive weight management programme overseen by healthcare professionals.

Long-Term Cost Considerations

Weight loss medications like mounjaro vs wegovy uk treatments are typically prescribed for extended periods — often 6-12 months or longer, depending on individual response and goals. Budgeting for ongoing monthly costs is essential. At Cured Pharmacy, we offer subscription options that ensure uninterrupted treatment at the lowest possible price point, with the flexibility to adjust or pause as your needs change. Our clinical team regularly reviews your progress to ensure the treatment remains appropriate and cost-effective for your circumstances.

Which Should You Choose: Mounjaro vs Wegovy UK Decision Framework

Deciding between mounjaro vs wegovy uk treatments isn't purely about efficacy numbers — it involves weighing clinical evidence, side effect tolerance, cost, and individual health factors. If maximising weight loss is your primary goal and budget permits, Mounjaro's superior trial results make it a compelling choice, particularly at higher doses [2][3]. However, Wegovy remains an excellent option with substantial evidence, a slightly better-tolerated side effect profile in some studies, and a lower price point [1].

Certain medical conditions may influence your prescriber's recommendation. Both medications are contraindicated in pregnancy, and both require caution in patients with pancreatitis history, severe gastrointestinal disease, or diabetic retinopathy. Your BMI, weight loss goals, previous medication responses, and budget will all factor into the clinical decision. At Cured Pharmacy, our UK-registered prescribers conduct thorough assessments considering all these variables, ensuring you receive a personalised recommendation rather than a one-size-fits-all approach. Every prescription is subject to clinical approval, and our superintendent pharmacist Tarun Kumar (GPhC 2233073) oversees all dispensing to maintain the highest safety and quality standards.

Starting Your Treatment Journey

Beginning either mounjaro vs wegovy uk treatment is straightforward at Cured Pharmacy. Complete our confidential online clinical assessment in under three minutes, and a UK-registered prescriber will review your information, typically within 24 hours. If approved, your medication is dispensed by our GPhC-registered pharmacy (9012511) and delivered discreetly to your door, often with next-day delivery options. We provide ongoing clinical support, dose adjustment guidance, and prescription renewals throughout your weight loss journey, ensuring you never feel alone in the process.

Scientific References

  1. Wilding, J. P., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., ... & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  2. Frías, J. P., Davies, M. J., Rosenstock, J., Pérez Manghi, F. C., Fernández Landó, L., Bergman, B. K., ... & SURPASS-2 Investigators. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. New England Journal of Medicine, 385(6), 503-515. [accessed 15 August 2026]
  3. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., Wharton, S., Connery, L., Alves, B., ... & SURMOUNT-1 Investigators. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-218. [accessed 15 August 2026]
  4. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  5. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  6. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

Trusted by thousands

Real people, real results

Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Is Mounjaro more effective than Wegovy for weight loss in the UK?
Clinical trials show Mounjaro (tirzepatide) achieves greater average weight loss than Wegovy (semaglutide) — up to 22.5% versus 14.9% in respective studies. The SURPASS-2 head-to-head trial confirmed tirzepatide's superior efficacy, though both medications deliver clinically significant results when used as prescribed.
Can I switch from Wegovy to Mounjaro or vice versa in the UK?
Switching between mounjaro vs wegovy uk treatments is possible under prescriber guidance. Your clinician will determine appropriate starting doses based on your current treatment, response, and tolerance. At Cured Pharmacy, our prescribers can facilitate switches during your regular review consultations, ensuring safe transitions between medications.
Which has fewer side effects: Mounjaro or Wegovy?
Both mounjaro vs wegovy uk medications share similar gastrointestinal side effect profiles, with nausea, diarrhoea, and vomiting being most common. Some studies suggest slightly higher rates with tirzepatide, though discontinuation rates remain comparable. Individual tolerance varies, and gradual dose escalation helps minimise symptoms with both treatments.
How long does it take to see results with Mounjaro vs Wegovy UK treatments?
Most patients notice appetite reduction within the first few weeks of either mounjaro vs wegovy uk treatment, with measurable weight loss typically evident by 4-8 weeks. Maximum effects develop over 6-12 months as you reach maintenance doses. Clinical trials measured outcomes at 68-72 weeks, reflecting the long-term nature of these therapies.
Do I need a prescription for Mounjaro or Wegovy in the UK?
Yes, both Mounjaro and Wegovy are prescription-only medicines in the UK, requiring clinical assessment by a registered prescriber. At Cured Pharmacy, our UK-based clinical team conducts thorough online consultations to ensure suitability before prescribing either medication, in full compliance with MHRA and GPhC regulations.
Can I use Mounjaro or Wegovy if I don't have diabetes?
Yes, both mounjaro vs wegovy uk medications are licensed for weight management in adults without diabetes who meet specific BMI criteria. Wegovy is specifically licensed for obesity treatment, whilst Mounjaro has demonstrated efficacy in non-diabetic populations in the SURMOUNT trials. Your prescriber will assess your eligibility during consultation.
What's the cheapest way to get Mounjaro or Wegovy in the UK?
Cured Pharmacy offers the lowest UK prices for both treatments: Wegovy from £124.99 and Mounjaro from £124.99, with £20 off your first order using code Weightlossnew. Our transparent pricing includes clinical assessment, prescription, and discreet delivery, with no hidden fees or separate consultation charges.
How do I inject Mounjaro or Wegovy at home?
Both mounjaro vs wegovy uk treatments come in pre-filled injection pens designed for easy self-administration once weekly. You'll inject subcutaneously into your abdomen, thigh, or upper arm, rotating sites each week. Our clinical team at Cured Pharmacy provides detailed injection technique instructions and video guidance when you receive your first prescription, ensuring you feel confident throughout treatment.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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