Wegovy vs Mounjaro UK: Compare Weight Loss Injections

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Cheapest Wegovy vs Mounjaro UK - Price From £69.00

Compare Wegovy and Mounjaro at the cheapest UK price from £124.99, plus save £20 off your first order with code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£99 £79.00

£19.75 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £99
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy Oral Pill
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
Start Consultation
Wegovy Oral Pill
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
Start Consultation
Wegovy Oral Pill
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy Oral Pill
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Wegovy vs Mounjaro: Compare UK Weight Loss Injections

Published on: June 03, 2026

Choosing between treatments requires a thorough wegovy vs mounjaro uk comparison to understand which injectable best suits your weight loss goals. Both are MHRA-licensed GLP-1 receptor agonists proven in clinical trials, but they differ in mechanism, efficacy, dosing schedules, and side effect profiles. At Cured Pharmacy, our UK-registered clinical team helps you navigate these options with transparent pricing and expert guidance.

How Wegovy and Mounjaro Work Differently

Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics the natural hormone glucagon-like peptide-1 to regulate appetite and blood sugar levels [1]. By activating GLP-1 receptors in the brain and pancreas, semaglutide slows gastric emptying, increases feelings of fullness, and reduces hunger signals between meals.

Mounjaro contains tirzepatide, the UK's first dual GIP/GLP-1 receptor agonist, activating both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 pathways simultaneously [2]. This dual mechanism produces enhanced metabolic effects compared to single-pathway treatments, with clinical trials demonstrating superior weight reduction outcomes.

The dual-action approach of tirzepatide affects insulin secretion, glucagon suppression, and energy expenditure through complementary pathways, which may explain why Mounjaro achieved greater average weight loss in head-to-head comparative studies [2][3].

Clinical Trial Results: Wegovy vs Mounjaro Weight Loss Efficacy

In the STEP 1 trial, adults using Wegovy achieved an average body weight reduction of 14.9% over 68 weeks, with 83.5% of participants losing at least 5% of their initial body weight [1]. Participants on the maximum 2.4mg weekly dose experienced consistent weight loss throughout the trial period, with improvements in cardiovascular risk markers.

The SURPASS-2 trial directly compared tirzepatide against semaglutide in adults with type 2 diabetes. Patients on the highest tirzepatide dose (15mg) achieved average weight loss of 11.2kg compared to 5.7kg with semaglutide 1mg over 40 weeks [3]. Subsequent obesity-focused trials showed even greater results, with SURMOUNT-1 demonstrating average weight reductions up to 22.5% with tirzepatide 15mg over 72 weeks [2].

Both medications show dose-dependent efficacy, meaning higher prescribed doses generally correlate with greater weight loss, subject to individual tolerability and prescriber assessment [1][2]. Your UK prescriber will determine the appropriate starting dose and titration schedule based on your medical history and treatment response.

Real-World Weight Loss Expectations

Clinical trial results represent controlled conditions with dietary counselling and regular monitoring. Real-world outcomes vary based on adherence, lifestyle modifications, baseline metabolic health, and individual response to treatment. Most patients begin seeing measurable weight loss within 4-8 weeks of starting either medication, with continued gradual reduction over subsequent months when combined with reduced-calorie diet and increased physical activity.

Dosing Schedules and Administration

Both Wegovy and Mounjaro are administered as once-weekly subcutaneous injections using pre-filled pens, typically into the abdomen, thigh, or upper arm. The injection site should be rotated each week to minimise skin reactions.

Wegovy follows a fixed dose escalation schedule starting at 0.25mg weekly, increasing every four weeks through 0.5mg, 1mg, and 1.7mg, reaching the maintenance dose of 2.4mg by week 17 [4]. This gradual titration helps minimise gastrointestinal side effects as your body adjusts to the medication.

Mounjaro starts at 2.5mg weekly with dose increases every four weeks as tolerated, progressing through 5mg, 7.5mg, 10mg, 12.5mg, and up to a maximum of 15mg weekly [5]. The slower titration and wider dose range allow for more personalised treatment optimisation based on individual response and tolerability.

What Happens If You Miss a Dose

For both medications, if you miss a dose and fewer than five days have passed since your scheduled injection day, take it as soon as you remember. If more than five days have passed, skip the missed dose and resume your normal weekly schedule. Never take two doses within three days of each other, as this increases the risk of gastrointestinal side effects.

Feature Wegovy (Semaglutide) Mounjaro (Tirzepatide)
Active Ingredient Semaglutide (GLP-1 agonist) Tirzepatide (dual GIP/GLP-1 agonist)
Injection Frequency Once weekly Once weekly
Starting Dose 0.25mg weekly 2.5mg weekly
Maximum Dose 2.4mg weekly 15mg weekly
Average Weight Loss (trials) Up to 14.9% over 68 weeks Up to 22.5% over 72 weeks
Titration Period 16 weeks to maintenance 20+ weeks to maximum dose
Price at Cured Pharmacy From £69.00 From £69.00
MHRA Approval Date 2022 (weight management) 2023 (weight management)

Side Effects: What to Expect with Each Treatment

The most common side effects for both Wegovy and Mounjaro are gastrointestinal, including nausea, diarrhoea, vomiting, constipation, and abdominal discomfort [1][2]. These effects typically occur during dose escalation phases and often diminish as treatment continues, though some patients experience persistent symptoms.

In clinical trials, nausea occurred in approximately 44% of Wegovy users and 34-43% of Mounjaro users depending on dose, with most cases rated as mild to moderate [1][2]. Eating smaller, more frequent meals and avoiding high-fat foods may help manage these symptoms.

Both medications carry similar warnings regarding thyroid C-cell tumours observed in rodent studies, pancreatitis risk, gallbladder problems, and hypoglycaemia when used with insulin or sulfonylureas [4][5]. Neither should be used if you have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.

Some patients report injection site reactions, fatigue, or changes in taste. Serious allergic reactions are rare but require immediate medical attention if you experience difficulty breathing, severe rash, or facial swelling.

Cost Comparison and UK Availability

At Cured Pharmacy, Wegovy starts from £135.00 per pen, representing competitive UK pricing with transparent upfront costs shown before your clinical consultation. The final price depends on your prescribed dose and treatment duration, determined by your UK prescriber following assessment.

Pricing structures across UK pharmacies vary based on dose strength, supply duration, and whether you're purchasing maintenance doses or following the initial titration schedule. Cured Pharmacy guarantees the lowest prices in the UK with no hidden consultation fees or prescription charges.

Both medications are available through private prescription only in the UK, as NHS availability remains limited to specialist weight management services in most areas. All purchases require completion of a free online clinical assessment by a UK-registered prescriber, typically completed in under three minutes.

Insurance and NHS Coverage

NHS prescription of GLP-1 medications for weight loss follows strict NICE guidelines, typically reserved for patients with BMI ≥35 with weight-related complications or BMI ≥30 with specific conditions, accessed through specialist services. Private prescriptions offer faster access without lengthy waiting lists, with treatment costs not typically covered by standard health insurance policies in the UK.

Which Treatment Is Right for You: Wegovy vs Mounjaro UK

Your choice between Wegovy and Mounjaro depends on multiple factors including your weight loss goals, medical history, tolerance for side effects, dosing preferences, and budget considerations. Patients seeking maximum weight loss outcomes may prefer Mounjaro based on superior trial results, whilst those prioritising established long-term safety data and lower starting costs may choose Wegovy.

Certain medical conditions influence suitability for each medication. Your UK prescriber will review contraindications including previous pancreatitis, severe gastrointestinal disease, diabetic retinopathy complications, and kidney function. Both medications require caution in patients with history of eating disorders or depression.

The online consultation at Cured Pharmacy includes a comprehensive medical questionnaire reviewed by our UK-registered clinical team led by Superintendent Pharmacist Tarun Kumar (GPhC 2233073). Based on your responses, our prescribers recommend the most appropriate treatment or suggest alternative options if GLP-1 medications aren't suitable.

Many patients achieve successful weight loss with either medication when combined with sustainable lifestyle changes. The 'best' choice is the one you can adhere to consistently, tolerate well, and afford long-term, as weight management typically requires ongoing treatment to maintain results.

Starting Your Treatment Journey

Beginning treatment involves completing your free online assessment, receiving prescriber approval, and having your medication dispensed from our UK-registered pharmacy with discreet next-day delivery. Our clinical team remains available throughout your treatment for dose adjustments, side effect management, and ongoing support as you progress towards your weight loss goals.

Scientific References

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183 [accessed 13 August 2026]
  2. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205–216. https://doi.org/10.1056/NEJMoa2206038 [accessed 13 August 2026]
  3. Frías, J. P., Davies, M. J., Rosenstock, J., et al. (2021). Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. New England Journal of Medicine, 385(6), 503–515. https://doi.org/10.1056/NEJMoa2107519 [accessed 13 August 2026]
  4. Novo Nordisk. (2023). Wegovy (semaglutide) Summary of Product Characteristics. Medicines and Healthcare products Regulatory Agency (MHRA). Retrieved from https://www.gov.uk/ [accessed 13 August 2026]
  5. Eli Lilly. (2023). Mounjaro (tirzepatide) Summary of Product Characteristics. Medicines and Healthcare products Regulatory Agency (MHRA). Retrieved from https://www.gov.uk/ [accessed 13 August 2026]
  6. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 13 August 2026.
  7. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 13 August 2026.
  8. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 13 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Individual results may vary, and weight loss outcomes depend on adherence to treatment, lifestyle modifications, and individual metabolic factors.

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Real people, real results

Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Is Mounjaro better than Wegovy for weight loss?
Clinical trials show Mounjaro (tirzepatide) achieved greater average weight loss than Wegovy (semaglutide), with SURMOUNT-1 demonstrating up to 22.5% body weight reduction compared to 14.9% with Wegovy in respective trials. Individual results vary based on adherence, lifestyle factors, and metabolic response.
Can I switch from Wegovy to Mounjaro or vice versa?
Yes, switching between GLP-1 medications is possible under prescriber supervision. Your UK clinician will determine appropriate transition timing and starting dose based on your current treatment response, side effect profile, and medical history to ensure safe changeover.
How long does it take to see results with Wegovy vs Mounjaro?
Most patients notice initial weight loss within 4-8 weeks of starting either medication, with continued gradual reduction over subsequent months during dose escalation. Maximum effects typically occur after reaching maintenance doses and continuing treatment for 6-12 months alongside lifestyle modifications.
Do Wegovy and Mounjaro have the same side effects?
Both medications share similar gastrointestinal side effects including nausea, diarrhoea, and vomiting, though incidence rates differ slightly between trials. Mounjaro's dual mechanism may produce different tolerability profiles in individual patients, which your prescriber will monitor during treatment.
Can I use Wegovy or Mounjaro if I have diabetes?
Both medications are licensed for weight management in adults with or without type 2 diabetes, though dose adjustments to existing diabetes medications may be necessary to prevent hypoglycaemia. Your UK prescriber will review your current diabetes treatment and HbA1c levels during assessment.
How much does the full wegovy vs mounjaro uk treatment cost?
Treatment costs vary based on prescribed dose and duration. At Cured Pharmacy, Wegovy starts from £135.00 and Mounjaro from £124.99 per pen, with transparent pricing shown before consultation. Most patients require ongoing treatment, so discuss long-term affordability with your prescriber.
What happens when I stop taking Wegovy or Mounjaro?
Weight regain is common after discontinuing GLP-1 medications, as the appetite-suppressing effects cease once treatment stops. Maintaining weight loss typically requires ongoing medication alongside sustained lifestyle changes, though some patients successfully transition to maintenance strategies under medical supervision.
Are Wegovy and Mounjaro available on the NHS?
NHS availability remains limited to specialist weight management services following strict NICE criteria, typically for patients with BMI ≥35 with complications. Private prescription through UK-registered pharmacies like Cured Pharmacy offers faster access without lengthy NHS waiting lists, subject to clinical assessment.
Is Mounjaro or Wegovy cheaper in the UK?
Mounjaro starts at £124.99 for the 2.5mg dose, while Wegovy starts at £69.00 for the 0.25mg starter dose. However, Mounjaro's higher doses deliver stronger results per injection, making it cost-effective for many patients. Cured Pharmacy offers both at the cheapest UK prices with transparent dose-by-dose pricing.
Which is better for weight loss - Wegovy or Mounjaro?
Clinical trials show Mounjaro typically leads to greater average weight loss than Wegovy, as it targets both GLP-1 and GIP receptors. However, individual results vary based on your health profile, tolerance, and lifestyle. Cured Pharmacy's UK-registered prescribers will help you choose the right treatment during your free online consultation.
Can I switch from Wegovy to Mounjaro in the UK?
Yes, you can switch from Wegovy to Mounjaro under medical guidance to ensure safe dose transition and minimise side effects. Cured Pharmacy's prescribers will review your current treatment and weight loss progress before approving a switch. Always complete a new consultation when changing medications.
Does Mounjaro work faster than Wegovy for weight loss?
Mounjaro often shows weight loss results slightly faster due to its dual-action formula targeting GLP-1 and GIP receptors. Most patients notice appetite reduction within the first week on either medication. Cured Pharmacy provides ongoing support to track your progress and adjust doses as needed for optimal results.
Are Wegovy and Mounjaro available on the NHS in the UK?
Both medications have very limited NHS availability due to supply constraints and strict eligibility criteria, with long waiting lists in most areas. Cured Pharmacy offers a faster, affordable private option with Mounjaro from £124.99 and same-day prescription approval. You'll receive genuine medication from UK-licensed pharmacies with full clinical support.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 13 August 2026

Last updated on 13 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 13 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (13 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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