Wegovy Mounjaro Dose Equivalent UK - Compare Prices

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Cheapest Wegovy Mounjaro Dose Equivalent UK - From £124.99

Compare Wegovy and Mounjaro at the cheapest UK price from £124.99 with £20 off using code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Understanding Wegovy Mounjaro Dose Equivalent: A UK Clinical Comparison

Understanding the wegovy mounjaro dose equivalent is essential for patients and prescribers comparing these two leading weight loss medications in the UK. Whilst both Wegovy (semaglutide) and Mounjaro (tirzepatide) are GLP-1 receptor agonists licensed for weight management, they work through different mechanisms and follow distinct dosing schedules that cannot be directly converted milligram-for-milligram. This comprehensive guide explains how these medications compare in terms of dosing, efficacy, and clinical outcomes based on the latest trial data.

How Wegovy Mounjaro Dose Equivalent Differs in Mechanism

The wegovy mounjaro dose equivalent question is complicated by their fundamentally different mechanisms of action. Wegovy contains semaglutide, a selective GLP-1 receptor agonist, whilst Mounjaro contains tirzepatide, a dual GIP/GLP-1 receptor agonist [1]. This dual action means Mounjaro activates both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors, potentially explaining why direct dose comparisons are not clinically meaningful.

In the STEP trials, Wegovy demonstrated an average weight loss of 15% of body weight at the 2.4mg weekly maintenance dose [2]. Meanwhile, the SURPASS trials showed Mounjaro achieving up to 22.5% average weight loss at the 15mg maintenance dose [3]. However, these outcomes cannot be attributed solely to dose differences, as the dual receptor mechanism of tirzepatide contributes significantly to its efficacy profile. Both medications require gradual dose escalation under UK prescriber supervision to minimise gastrointestinal side effects.

Wegovy Mounjaro Dose Equivalent Escalation Schedules

Rather than seeking a wegovy mounjaro dose equivalent conversion, UK prescribers follow each medication's licensed escalation schedule. Wegovy begins at 0.25mg weekly, increasing monthly through 0.5mg, 1mg, and 1.7mg before reaching the 2.4mg maintenance dose [4]. This five-month escalation period allows the body to adapt to increasing GLP-1 receptor stimulation.

Mounjaro follows a different trajectory, starting at 2.5mg weekly and increasing every four weeks through 5mg, 7.5mg, 10mg, 12.5mg, with a maximum dose of 15mg weekly [1]. The escalation period can extend up to five months depending on individual tolerance and clinical response. These distinct schedules reflect each medication's unique pharmacokinetic profile and receptor binding characteristics.

Clinical Considerations for Dose Titration

UK prescribers assess individual patient response at each dose level before advancing. Factors influencing the wegovy mounjaro dose equivalent discussion include baseline BMI, comorbidities such as type 2 diabetes, and tolerability of gastrointestinal side effects. Subject to prescriber approval, some patients may remain on lower maintenance doses if they achieve their weight loss targets with acceptable side effect profiles. The MHRA-approved product information for both medications emphasises individualised dosing based on clinical response rather than rigid equivalence ratios.

Wegovy Mounjaro Dose Equivalent in Clinical Trial Outcomes

When comparing wegovy mounjaro dose equivalent effects, clinical trial data provides the most robust evidence. The STEP 1 trial demonstrated that Wegovy 2.4mg weekly produced an average 14.9% weight reduction over 68 weeks in adults with obesity [2]. The SURPASS-2 trial directly compared tirzepatide to semaglutide 1mg (the diabetes dose, not the Wegovy 2.4mg dose), showing superior weight loss with tirzepatide across all dose levels [5].

More recently, the SURMOUNT-1 trial evaluated Mounjaro specifically for weight management in adults without diabetes, showing average weight reductions of 15%, 19.5%, and 22.5% for the 5mg, 10mg, and 15mg doses respectively over 72 weeks [3]. Whilst head-to-head trials comparing Mounjaro to Wegovy 2.4mg are limited, indirect comparisons suggest Mounjaro may produce greater average weight loss, though individual responses vary considerably. Both medications require ongoing treatment to maintain weight loss, as discontinuation typically results in weight regain.

Cardiovascular and Metabolic Benefits

Beyond the wegovy mounjaro dose equivalent question for weight loss, both medications demonstrate cardiovascular and metabolic benefits. The SELECT trial showed Wegovy reduced major adverse cardiovascular events by 20% in adults with obesity and established cardiovascular disease [6]. Mounjaro trials have consistently shown improvements in HbA1c, blood pressure, and lipid profiles, with ongoing cardiovascular outcome trials expected to report in coming years. UK prescribers consider these broader health benefits when selecting between medications, not just the dose equivalence for weight reduction.

Medication Active Ingredient Mechanism Starting Dose Maintenance Dose Price from
Wegovy Semaglutide GLP-1 agonist 0.25mg weekly 2.4mg weekly £89.00
Mounjaro Tirzepatide Dual GIP/GLP-1 agonist 2.5mg weekly 5-15mg weekly £145.00

Understanding Wegovy Mounjaro Dose Equivalent Costs in the UK

The wegovy mounjaro dose equivalent discussion extends to treatment costs, which vary significantly across UK pharmacies. At Cured Pharmacy, Wegovy is available from £124.99 and Mounjaro from £124.99, with transparent pricing displayed before consultation. New patients can Save £20 off their first order using code Weightlossnew, making these treatments more accessible.

Monthly treatment costs depend on which dose you're prescribed during the escalation phase and at maintenance. As Mounjaro doses increase from 2.5mg to 15mg, the cost per pen remains consistent, but you progress through different strength pens. Similarly, Wegovy pens are available in the specific doses needed for the escalation schedule. All prescription treatments at Cured Pharmacy require clinical assessment by a UK-registered prescriber, ensuring safe and appropriate use. Our superintendent pharmacist, Tarun Kumar (GPhC 2233073), oversees all dispensing to guarantee genuine UK-licensed medications.

Wegovy Mounjaro Dose Equivalent Side Effect Profiles

When considering wegovy mounjaro dose equivalent tolerability, both medications share similar side effect profiles due to their GLP-1 receptor activity. The most common adverse effects include nausea, diarrhoea, vomiting, constipation, and abdominal discomfort, typically most pronounced during dose escalation [1][4]. These gastrointestinal symptoms usually diminish over time as the body adapts.

Clinical trial data suggests side effects are dose-dependent for both medications. In the STEP trials, approximately 74% of Wegovy patients experienced gastrointestinal adverse events, compared to 47% on placebo [2]. The SURPASS trials reported similar rates with Mounjaro, with higher doses associated with increased incidence [3]. Serious side effects such as pancreatitis, gallbladder disease, and thyroid C-cell tumours are rare but require monitoring. UK prescribers assess individual risk factors before prescribing and provide guidance on managing common side effects through dietary modifications and gradual dose titration.

Contraindications and Precautions

Regardless of the wegovy mounjaro dose equivalent you're considering, both medications are contraindicated in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. They should be used with caution in patients with severe gastrointestinal disease, history of pancreatitis, or diabetic retinopathy. Pregnancy and breastfeeding are contraindications for both medications. UK prescribers conduct thorough medical assessments to identify any contraindications before prescribing either treatment.

Choosing Between Wegovy Mounjaro Dose Equivalent Options

Rather than focusing solely on wegovy mounjaro dose equivalent conversions, UK patients and prescribers should consider multiple factors when selecting treatment. Individual response to medication varies considerably, with some patients achieving excellent results on Wegovy whilst others may benefit more from Mounjaro's dual receptor mechanism. Clinical factors such as presence of type 2 diabetes, cardiovascular disease, and previous medication trials influence the decision.

Practical considerations include injection frequency (both are weekly), cost, availability, and individual tolerance of side effects. At Cured Pharmacy, our UK-registered clinical team provides free online consultations under 3 minutes to assess suitability for either medication. We offer competitive UK pricing with no hidden fees, 100% discreet packaging, and genuine UK-licensed medicines only. Our lowest prices guaranteed policy ensures you receive the cheapest UK price without compromising on clinical safety or pharmaceutical quality.

The wegovy mounjaro dose equivalent question ultimately has no single answer, as these are distinct medications with different mechanisms, dosing schedules, and efficacy profiles. Subject to prescriber approval, your clinician will recommend the most appropriate option based on your individual medical history, weight loss goals, and tolerability. Both medications have demonstrated significant weight loss in clinical trials and are valuable tools in managing obesity when combined with lifestyle modifications including reduced-calorie diet and increased physical activity.

Scientific References

  1. Jastreboff, A. M., et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. [accessed 15 August 2026]
  2. Wilding, J. P., et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  3. Garvey, W. T., et al. (2023). Tirzepatide for the treatment of obesity: rationale and design of the SURMOUNT clinical development program. Obesity, 31(1), 96-110. [accessed 15 August 2026]
  4. Electronic Medicines Compendium. (2023). Wegovy 2.4 mg solution for injection in pre-filled pen - Summary of Product Characteristics. [accessed 15 August 2026]
  5. Frías, J. P., et al. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes (SURPASS-2): a randomised, open-label, phase 3 trial. Lancet, 398(10295), 64-77. [accessed 15 August 2026]
  6. Lincoff, A. M., et al. (2023). Semaglutide and cardiovascular outcomes in obesity without diabetes. New England Journal of Medicine, 389(24), 2221-2232. [accessed 15 August 2026]
  7. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  8. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  9. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

What is the wegovy mounjaro dose equivalent for weight loss?
There is no direct milligram-to-milligram wegovy mounjaro dose equivalent because they work through different mechanisms. Wegovy (semaglutide) is a GLP-1 agonist with a 2.4mg maintenance dose, whilst Mounjaro (tirzepatide) is a dual GIP/GLP-1 agonist with maintenance doses ranging from 5-15mg weekly.
Can I switch from Wegovy to Mounjaro or vice versa?
Switching between Wegovy and Mounjaro requires clinical assessment by a UK prescriber, as there is no established wegovy mounjaro dose equivalent conversion protocol. Your prescriber will typically start the new medication at its initial dose and titrate according to the licensed schedule.
Which is more effective for weight loss, Wegovy or Mounjaro?
Clinical trials suggest Mounjaro may produce slightly greater average weight loss (up to 22.5%) compared to Wegovy (average 15%), though individual responses vary considerably. The wegovy mounjaro dose equivalent question is less important than finding which medication works best for your individual circumstances.
How long does it take to reach maintenance dose for each medication?
Wegovy requires approximately 16-20 weeks to reach the 2.4mg maintenance dose, whilst Mounjaro takes 12-20 weeks depending on which maintenance dose (5mg, 10mg, 12.5mg, or 15mg) your prescriber determines is appropriate for you.
Are the side effects different between Wegovy and Mounjaro?
Both medications share similar gastrointestinal side effects including nausea, diarrhoea, and vomiting due to GLP-1 receptor activity. The wegovy mounjaro dose equivalent side effect profile is comparable, though individual tolerance varies and may influence which medication suits you better.
Can I use Wegovy and Mounjaro together?
No, Wegovy and Mounjaro should not be used together as they work through overlapping mechanisms and combining them would increase the risk of side effects without additional benefit. Your UK prescriber will recommend one medication based on your individual needs.
How much does wegovy mounjaro dose equivalent treatment cost in the UK?
At Cured Pharmacy, Wegovy starts from £124.99 and Mounjaro from £124.99, with £20 off your first order using code Weightlossnew. Monthly costs depend on your prescribed dose during escalation and maintenance phases.
Do I need a prescription for Wegovy or Mounjaro in the UK?
Yes, both Wegovy and Mounjaro are prescription-only medications requiring clinical assessment by a UK-registered prescriber. Cured Pharmacy offers free online consultations under 3 minutes to determine suitability for either treatment.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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