Ozempic vs Wegovy vs Mounjaro UK - Compare Prices 2025

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Ozempic vs Wegovy vs Mounjaro UK - Compare Cheapest

Compare Ozempic, Wegovy and Mounjaro at the cheapest UK price from £124.99 — Save £20 with code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Ozempic vs Wegovy vs Mounjaro UK: Which Weight Loss Injection Is Right for You?

When comparing Ozempic vs Wegovy vs Mounjaro UK options, patients often ask which injectable delivers the most effective weight loss with the fewest side effects. All three medications—semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro)—are GLP-1 receptor agonists licensed by the MHRA, but they differ significantly in mechanism, dosing schedules, and clinical trial outcomes. As a UK-registered pharmacy with transparent pricing and expert clinical oversight, Cured Pharmacy helps you navigate these choices with confidence.

Ozempic vs Wegovy vs Mounjaro UK: Active Ingredients and Mechanisms

Understanding the Ozempic vs Wegovy vs Mounjaro UK comparison begins with their active ingredients. Ozempic and Wegovy both contain semaglutide, a GLP-1 receptor agonist that mimics the incretin hormone to reduce appetite and slow gastric emptying [1]. Mounjaro, by contrast, contains tirzepatide—a dual GIP/GLP-1 receptor agonist that targets two incretin pathways simultaneously, potentially offering enhanced weight loss efficacy [2].

While Ozempic was originally licensed for type 2 diabetes management, Wegovy received specific MHRA approval for chronic weight management in adults with a BMI ≥30 kg/m² or ≥27 kg/m² with weight-related comorbidities [1]. Mounjaro also holds dual licensing: for diabetes and, more recently, for weight management under the brand name in certain markets. All three require subcutaneous injection once weekly, though their dose escalation schedules differ. UK prescribers assess individual patient factors—including baseline BMI, comorbidities, and tolerance to gastrointestinal side effects—before recommending a specific agent.

The dual-agonist mechanism of Mounjaro has shown superior weight reduction in head-to-head trials. The SURPASS-2 trial demonstrated that tirzepatide 15 mg achieved an average weight loss of 12.4 kg compared to 6.2 kg with semaglutide 1 mg over 40 weeks [2]. However, Wegovy's higher 2.4 mg semaglutide dose (used specifically for weight management) narrows this gap, with the STEP 1 trial reporting an average 14.9% body weight reduction at 68 weeks [1]. Ozempic, typically prescribed at 0.5–1 mg for diabetes, produces modest weight loss as a secondary benefit rather than a primary indication.

Ozempic vs Wegovy vs Mounjaro UK: Dosing Schedules and Titration

Dosing protocols are a key differentiator in the Ozempic vs Wegovy vs Mounjaro UK landscape. Wegovy follows a structured five-step titration over 16–20 weeks: 0.25 mg weekly for four weeks, then 0.5 mg, 1 mg, 1.7 mg, and finally the maintenance dose of 2.4 mg [1]. This gradual escalation minimises gastrointestinal side effects such as nausea and vomiting, which are the most common reasons for discontinuation.

Mounjaro's titration is similarly cautious but extends across a broader dose range. Patients start at 2.5 mg weekly, increasing every four weeks through 5 mg, 7.5 mg, 10 mg, 12.5 mg, and up to a maximum of 15 mg [2]. The flexibility to stop at intermediate doses allows prescribers to balance efficacy with tolerability on an individual basis. Ozempic, when used off-label for weight loss, typically remains at 0.5–1 mg weekly, as higher doses are not licensed for this indication in the UK.

Missed doses require careful management. For all three agents, if a dose is missed and fewer than five days have passed, it should be administered as soon as possible. If more than five days have elapsed, the missed dose should be skipped, and the regular schedule resumed. UK prescribers emphasise adherence to the weekly injection day to maintain stable plasma concentrations and optimise outcomes.

Injection Technique and Device Differences

All three medications are supplied in pre-filled, single-use pens designed for subcutaneous injection into the abdomen, thigh, or upper arm. Wegovy and Ozempic pens deliver fixed doses per injection, whereas Mounjaro's KwikPen allows dose adjustment via a dial mechanism. Patients receive training from their prescriber or pharmacist on proper injection technique, needle disposal, and site rotation to prevent lipodystrophy. Cured Pharmacy provides comprehensive patient information leaflets and video tutorials with every prescription to ensure safe self-administration.

Ozempic vs Wegovy vs Mounjaro UK: Clinical Efficacy and Trial Data

Head-to-head comparisons reveal nuanced differences when evaluating Ozempic vs Wegovy vs Mounjaro UK efficacy. The STEP clinical trial programme for semaglutide 2.4 mg (Wegovy) demonstrated an average weight loss of 14.9% of baseline body weight over 68 weeks, with 83.5% of participants achieving at least 5% weight loss [1]. By contrast, the SURMOUNT-1 trial for tirzepatide showed dose-dependent reductions: 15.0% with the 5 mg dose, 19.5% with 10 mg, and 20.9% with 15 mg at 72 weeks [2].

Ozempic, when prescribed at 1 mg weekly for diabetes, produces average weight reductions of 4–6 kg—clinically meaningful but lower than the higher-dose semaglutide or tirzepatide formulations [3]. It is important to note that Ozempic is not licensed for weight management as a primary indication in the UK, and off-label use requires careful prescriber justification and patient counselling.

Beyond weight loss, all three agents improve cardiometabolic markers. Semaglutide has demonstrated cardiovascular risk reduction in the SUSTAIN-6 and SELECT trials, with significant decreases in major adverse cardiovascular events [3]. Tirzepatide's cardiovascular outcome trial (SURPASS-CVOT) is ongoing, with interim data suggesting favourable lipid and blood pressure effects [2]. UK prescribers consider these broader health benefits when selecting treatment, particularly for patients with obesity and coexisting type 2 diabetes or cardiovascular disease.

Treatment Active Ingredient Licensed Indication Maintenance Dose Average Weight Loss Starting Price
Wegovy Semaglutide Weight management 2.4 mg weekly 14.9% at 68 weeks From £89.00
Mounjaro Tirzepatide Diabetes & weight management 5–15 mg weekly Up to 20.9% at 72 weeks From £145.00
Ozempic Semaglutide Type 2 diabetes 0.5–1 mg weekly 4–6 kg (secondary outcome) Varies by dose

Ozempic vs Wegovy vs Mounjaro UK: Side Effects and Tolerability

Gastrointestinal side effects dominate the safety profile across the Ozempic vs Wegovy vs Mounjaro UK spectrum. Nausea, vomiting, diarrhoea, and constipation are reported in 20–50% of patients during dose escalation [1][2]. These symptoms typically diminish after 4–8 weeks as the body adapts, but they remain the leading cause of treatment discontinuation.

Tirzepatide's dual-agonist mechanism may confer a slightly higher incidence of nausea at equivalent weight loss magnitudes, though direct comparative trials are limited [2]. Rare but serious adverse events include pancreatitis, gallbladder disease, and thyroid C-cell tumours (observed in rodent studies, leading to a black-box warning in some jurisdictions). All three medications are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.

UK prescribers conduct thorough medical histories and monitor patients for signs of acute pancreatitis (persistent severe abdominal pain) and gallstones. Cured Pharmacy's clinical team reviews each patient's eligibility during the online consultation, ensuring contraindications are identified before prescribing. Patients are advised to report any unusual symptoms promptly and to attend follow-up assessments every 8–12 weeks.

Managing Side Effects in Clinical Practice

Practical strategies to minimise gastrointestinal symptoms include eating smaller, more frequent meals, avoiding high-fat foods, and staying well-hydrated. Some patients benefit from taking the injection in the evening to sleep through peak nausea periods. If side effects are intolerable, prescribers may slow the titration schedule or reduce the dose temporarily. Antiemetic medications are rarely needed but can be considered in severe cases. Open communication with your pharmacist or prescriber is essential to optimise tolerability while maintaining efficacy.

Ozempic vs Wegovy vs Mounjaro UK: Cost and Accessibility

Price is a decisive factor in the Ozempic vs Wegovy vs Mounjaro UK decision for many patients. At Cured Pharmacy, Wegovy is available from £124.99, Mounjaro from £124.99, and Ozempic pricing varies by dose and supply. All prices are displayed transparently before the online consultation, with no hidden fees or subscription traps. New patients receive £20 off their first order using code Weightlossnew, making Cured Pharmacy one of the most competitive UK sources for these treatments.

NHS availability remains limited. NICE guidelines recommend GLP-1 receptor agonists for weight management only in specialist tier 3 or 4 services, and supply shortages have restricted access further [4]. Most UK patients seeking these medications turn to registered online pharmacies like Cured Pharmacy, where prescriptions are issued following a clinical assessment by a UK-registered prescriber. The entire process—from consultation to delivery—takes under 48 hours in most cases, with discreet next-day shipping available.

When comparing total treatment costs, consider the maintenance dose and duration. Wegovy's 2.4 mg maintenance dose is typically continued long-term, whereas some patients on Mounjaro achieve target weight loss at lower doses (e.g., 7.5 or 10 mg), potentially reducing monthly expenditure. Your prescriber will discuss dose optimisation and cost-effectiveness during follow-up consultations.

Ozempic vs Wegovy vs Mounjaro UK: Which Should You Choose?

Selecting between Ozempic vs Wegovy vs Mounjaro UK options depends on your clinical profile, weight loss goals, and tolerance. Wegovy is the established first-line choice for weight management, backed by extensive STEP trial data and MHRA licensing specifically for obesity [1]. It offers a proven efficacy-to-tolerability ratio and is often the most accessible option at UK pharmacies.

Mounjaro may be preferred for patients seeking maximal weight loss or those who have not achieved target reductions on semaglutide. The SURPASS trials suggest superior efficacy at higher tirzepatide doses, though this comes with a modestly higher side effect burden and cost [2]. Patients with type 2 diabetes may benefit from Mounjaro's dual metabolic effects, including greater HbA1c reductions compared to semaglutide monotherapy.

Ozempic is generally not recommended as a first-line weight loss agent in the UK, given its lower licensed dose and primary indication for diabetes. However, some prescribers may consider it for patients with concurrent diabetes who require modest weight reduction alongside glycaemic control. Cured Pharmacy's clinical team evaluates your medical history, BMI, comorbidities, and previous treatment responses to recommend the most appropriate agent. All prescriptions are subject to approval by a UK-registered prescriber, ensuring safe and evidence-based care.

How to Start Treatment at Cured Pharmacy

Beginning your weight loss journey is straightforward. Complete the free online consultation (under 3 minutes), which covers your medical history, current medications, and weight loss goals. A UK-registered prescriber reviews your submission within 24 hours. If approved, your medication is dispensed by our GPhC-registered pharmacy and shipped in discreet packaging with next-day delivery. Follow-up consultations every 8–12 weeks ensure ongoing safety and dose optimisation. Use code Weightlossnew at checkout to Save £20 on your first order.

Scientific References

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., ... & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989–1002. [accessed 15 August 2026]
  2. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., Wharton, S., Connery, L., Alves, B., ... & Garvey, W. T. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205–216. [accessed 15 August 2026]
  3. Marso, S. P., Bain, S. C., Consoli, A., Eliaschewitz, F. G., Jódar, E., Leiter, L. A., ... & Zinman, B. (2016). Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. New England Journal of Medicine, 375(19), 1834–1844. [accessed 15 August 2026]
  4. National Institute for Health and Care Excellence. (2023). Semaglutide for managing overweight and obesity: Technology appraisal guidance [TA875]. NICE. [accessed 15 August 2026]
  5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

How much is Mounjaro 2.5mg?
Mounjaro 2.5mg costs from £124.99 at Cured Pharmacy, You just need to have a free online consultation, to check your eligibility.
How much is Mounjaro 5mg?
Mounjaro 5mg costs from £159.00 at Cured Pharmacy, You just need to have a free online consultation, to check your eligibility.
Which is better for weight loss: Ozempic vs Wegovy vs Mounjaro UK?
Mounjaro (tirzepatide) demonstrates the highest average weight loss in clinical trials (up to 20.9%), followed by Wegovy (14.9%). Ozempic is licensed for diabetes, not weight management, and produces lower weight reductions at standard doses.
Can I switch from Ozempic to Wegovy or Mounjaro in the UK?
Yes, switching is possible under prescriber supervision. Your clinician will assess your response to Ozempic and determine the appropriate starting dose for Wegovy or Mounjaro, typically resuming titration from a lower step to minimise side effects.
What are the main side effects when comparing Ozempic vs Wegovy vs Mounjaro UK?
All three cause similar gastrointestinal side effects—nausea, vomiting, diarrhoea, and constipation—most commonly during dose escalation. Tirzepatide may have a slightly higher nausea incidence, but individual tolerance varies widely.
Is Ozempic vs Wegovy vs Mounjaro UK available on the NHS?
NHS access is extremely limited due to NICE restrictions and supply shortages. Most UK patients obtain these medications through registered online pharmacies like Cured Pharmacy, where prescriptions are issued following a clinical assessment.
How long does it take to see results with Ozempic vs Wegovy vs Mounjaro UK?
Patients typically notice appetite suppression within 1–2 weeks and measurable weight loss by week 4–8. Maximum weight reduction occurs at 60–72 weeks, though significant progress is evident by 16–20 weeks in most cases.
Do I need a prescription for Ozempic vs Wegovy vs Mounjaro UK?
Yes, all three are prescription-only medications in the UK. Cured Pharmacy provides a free online consultation with a UK-registered prescriber, who reviews your eligibility and issues a prescription if clinically appropriate.
Can I use Ozempic vs Wegovy vs Mounjaro UK if I don't have diabetes?
Wegovy and Mounjaro are licensed for weight management in non-diabetic patients with a BMI ≥30 or ≥27 with comorbidities. Ozempic is licensed only for diabetes, though some prescribers use it off-label for weight loss.
What is the cheapest option when comparing Ozempic vs Wegovy vs Mounjaro UK prices?
Wegovy is the most affordable at Cured Pharmacy, starting from £124.99. Mounjaro starts at £124.99. Use code Weightlossnew for £20 off your first order, making Wegovy the cheapest UK option for effective weight loss.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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