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Utovlan Tablets

Utovlan Tablets

  • 1. Ozempic®️-equivalent therapy now available for weight management
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  • 3. May help reduce osteoarthritis-related pain
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  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Delays menstruation by up to 14 days effectively
  • ✔️ Treats heavy periods, endometriosis, and hormonal imbalance
  • ✔️ Contains clinically established norethisterone 5mg per tablet
  • ✔️ Period typically returns within 2–3 days of stopping
  • ✔️ Suitable for adult women needing short-term hormonal management

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What Are Norethisterone Tablets Used For?

 

Utovlan tablets contain norethisterone tablets 5mg as their active ingredient — a synthetic form of the female sex hormone progesterone. They're one of the most widely used hormonal treatments in the UK for managing menstruation and a range of gynaecological conditions. Whether you need to delay a period for a holiday, a sporting event, or a special occasion, or you're managing a longer-term hormonal condition, Utovlan offers a clinically established option. You can explore other treatments for women's health concerns in our women's health collection.

Norethisterone belongs to a class of medicines called progestogens. It has been used in clinical practice for decades and is well understood by healthcare professionals. It's available on prescription and, in some cases, through registered online pharmacies following an appropriate consultation.

 

How Do Utovlan Tablets Work?

 

Utovlan works by supplementing the body's natural progesterone levels. Normally, a drop in progesterone triggers the shedding of the uterine lining — your period. By keeping progesterone levels elevated artificially, Utovlan prevents that drop from occurring. Here's a simplified breakdown of the mechanism:

  • Norethisterone binds to progesterone receptors in the uterine lining (endometrium).
  • This maintains the endometrium in a stable, thickened state.
  • Menstruation is suppressed for as long as the tablets are taken.
  • Once you stop taking Utovlan, progesterone levels fall and your period typically begins within two to three days.

It's worth noting that Utovlan is not a contraceptive at the doses used for period delay. If you need contraception, speak to your GP or pharmacist about appropriate options.

 

Who Should Consider Using Utovlan Tablets?

 

Utovlan is suitable for adult women who need to temporarily delay menstruation or who are being treated for certain hormone-related conditions. It's not appropriate for everyone, so a consultation is always required before use.

  • Women wishing to delay their period for a holiday, wedding, or sporting event.
  • Women with endometriosis, where norethisterone may help manage symptoms.
  • Women experiencing dysfunctional uterine bleeding or menorrhagia (heavy periods).
  • Women with premenstrual syndrome (PMS) where hormonal management has been recommended.

It is not suitable for women who are pregnant, breastfeeding, or who have a history of blood clots, liver problems, or certain cancers. Always disclose your full medical history during your consultation.

 

How Does Utovlan Compare to Other Period Delay Options?

 

Feature Utovlan (Norethisterone 5mg) Combined Oral Contraceptive Pill
Active ingredient Norethisterone (progestogen only) Oestrogen + progestogen
Contraceptive effect No (at period delay doses) Yes
Suitable for non-pill users Yes No — requires existing use
Typical duration of use Up to 14 days for delay Varies by pill type

 

Is Utovlan Safe to Store and Use Long Term?

 

Utovlan tablets should be stored below 25°C, in a dry place away from direct sunlight, and kept out of the reach and sight of children. Do not use after the expiry date printed on the packaging. If you're managing a longer-term condition such as endometriosis, your doctor will advise on the appropriate duration of treatment — self-medicating with norethisterone tablets beyond the recommended period without medical supervision is not advised. If you're also managing pain alongside your hormonal condition, our pain relief collection may offer complementary support options.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Utovlan Tablets specifications
Treatment category Hormonal / Gynaecological
Mechanism of action Synthetic progestogen — maintains uterine lining to suppress menstruation
Effective for Period delay, endometriosis, dysfunctional uterine bleeding, menorrhagia
Suitable for Adult women (not suitable during pregnancy or breastfeeding)
Active ingredient Norethisterone 5mg
Pack sizes 30 tablets
Strengths 5mg
UK classification Prescription Only Medicine (POM)
Drug class Progestogen
Preparation Tablet
Route of administration Oral

Specifications of Utovlan Tablets

 

What Is Utovlan and What Is It Used For?

 

Utovlan tablets contain norethisterone 5mg, a synthetic progestogen used to treat a range of menstrual and gynaecological conditions. It is most commonly used to temporarily delay menstruation, but it also has clinical applications in managing endometriosis, dysfunctional uterine bleeding, premenstrual syndrome, and menorrhagia (heavy periods). Norethisterone works by mimicking the action of the naturally occurring hormone progesterone in the body.

Utovlan is a prescription-only medicine in the UK. It is not a contraceptive at the doses typically used for period delay, and patients should not assume it will prevent pregnancy.

 

What Do You Need to Know Before Using Utovlan?

 

Before taking Utovlan, it's essential to inform your prescriber or pharmacist of your full medical history. There are several situations where Utovlan should not be used:

  • You are pregnant or think you may be pregnant.
  • You are breastfeeding.
  • You have a history of venous thromboembolism (blood clots) or are at high risk.
  • You have severe liver disease or a history of liver tumours.
  • You have a history of hormone-sensitive cancers, such as breast cancer.
  • You have undiagnosed vaginal bleeding.
  • You have a history of arterial cardiovascular disease or stroke.

The following medicines may interact with Utovlan and reduce its effectiveness or increase the risk of side effects:

  • Enzyme-inducing medicines: rifampicin, carbamazepine, phenytoin, phenobarbital.
  • Herbal remedies: St John's Wort (Hypericum perforatum).
  • Ciclosporin — norethisterone may increase plasma levels.
  • Anticoagulants — effects may be altered; monitoring is advised.

 

How Should You Use Utovlan Tablets?

 

Always use Utovlan exactly as directed by your prescriber or pharmacist. Do not take more than the recommended dose. Swallow each tablet whole with a glass of water.

  1. Check the indication for which Utovlan has been prescribed — dosing varies by condition.
  2. For period delay: begin taking tablets three days before your period is expected.
  3. Take one tablet three times daily at evenly spaced intervals.
  4. Continue taking the tablets for as long as you wish to delay your period (maximum 14 days).
  5. Stop taking the tablets when you are ready for your period to begin — it should arrive within two to three days.
  6. If you vomit within two hours of taking a tablet, take another one as soon as possible.
Indication Age Group Dose Frequency
Period delay Adult women 5mg (1 tablet) Three times daily, starting 3 days before expected period
Endometriosis Adult women 10–15mg daily (as directed) As prescribed by doctor
Dysfunctional uterine bleeding Adult women 5mg (1 tablet) Three times daily for 10 days
Menorrhagia (heavy periods) Adult women 5mg (1 tablet) Three times daily from day 19 to 26 of cycle

 

What Are the Possible Side Effects of Utovlan?

 

Like all medicines, Utovlan can cause side effects, although not everyone experiences them. If you're also managing other aspects of your health, our women's health collection includes a range of supportive products. Below is a summary of known side effects:

Common side effects (may affect up to 1 in 10 people):

  • Nausea
  • Headache
  • Breast tenderness or discomfort
  • Mood changes, including low mood or irritability
  • Irregular vaginal bleeding or spotting
  • Bloating or fluid retention

Less common side effects (may affect up to 1 in 100 people):

  • Acne or skin changes
  • Decreased libido
  • Dizziness
  • Insomnia
  • Weight changes
  • Allergic skin reactions such as rash or urticaria

Seek immediate medical attention if you experience signs of a blood clot — such as sudden chest pain, breathlessness, leg swelling, or severe headache — as these may indicate a serious thromboembolic event.

 

How Should You Store Utovlan Tablets?

 

Correct storage helps maintain the quality and safety of your medication. If you're managing multiple health products at home, it's good practice to keep all medicines organised and clearly labelled. For other health essentials, browse our first aid collection.

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and moisture.
  • Do not store in the bathroom or near a sink.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the pack.
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Utovlan tablets online in the UK?

You can buy Utovlan tablets from Cured Pharmacy, a GPhC-registered online pharmacy in the UK. A short online consultation is required to confirm the medication is appropriate for you. Once approved by our pharmacist team, your order is dispatched promptly and discreetly.

How do Utovlan tablets work in the body?

Utovlan contains norethisterone, a synthetic progestogen that mimics the action of progesterone. It works by keeping the uterine lining stable, which prevents menstruation from occurring. Once you stop taking the tablets, progesterone levels fall and your period typically begins within two to three days.

How do I use Utovlan tablets to delay my period step by step?

Start taking one 5mg tablet three times a day, beginning three days before your period is expected. Continue taking the tablets for as long as you wish to delay your period, up to a maximum of 14 days. When you stop taking them, your period should arrive within two to three days.

What is the correct dose of Utovlan for period delay?

The standard dose for period delay is one 5mg norethisterone tablet taken three times daily. You should begin three days before your period is due and continue until you are ready for your period to start. Do not exceed 14 days of continuous use for this indication without medical advice.

What is the best time of day to take Utovlan tablets?

There is no single "best" time, but consistency matters. Try to take each dose at evenly spaced intervals throughout the day — for example, morning, afternoon, and evening. Taking tablets at the same times each day helps maintain stable hormone levels and reduces the risk of breakthrough bleeding.

What are the common side effects of Utovlan and how do I manage them?

Common side effects include nausea, headache, breast tenderness, mood changes, and irregular spotting. Taking tablets with food may help reduce nausea. If side effects are persistent or troublesome, speak to your pharmacist or GP — they may be able to suggest ways to manage them or review your treatment.

Who is not eligible to use Utovlan tablets?

Utovlan is not suitable for women who are pregnant, breastfeeding, or who have a history of blood clots, severe liver disease, or hormone-sensitive cancers. Women with undiagnosed vaginal bleeding or a history of stroke should also avoid it. Always complete a full medical consultation before use to confirm suitability.

What happens if I miss a dose of Utovlan?

If you miss a dose, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and carry on as normal — do not double up. Missing doses increases the risk of breakthrough bleeding, which may mean your period starts earlier than intended.

Does Utovlan work as a contraceptive?

No — Utovlan is not a contraceptive at the doses used for period delay. It will not protect you against pregnancy or sexually transmitted infections. If you need contraception, speak to your GP or sexual health clinic about appropriate options. You can also browse our condoms and sexual health collection for barrier method options.

What are the alternatives to Utovlan for delaying a period?

The main alternative for period delay is taking the combined oral contraceptive pill back-to-back, skipping the pill-free interval. This is only suitable for women already taking the pill. Speak to your GP or pharmacist about which approach is most appropriate for your circumstances and medical history.

Can Utovlan be used to treat endometriosis?

Yes — norethisterone is one of the hormonal treatments used to manage endometriosis, as it can suppress the growth of endometrial tissue outside the uterus. However, the dose used for endometriosis is typically higher than that used for period delay, and treatment should always be supervised by a doctor. The NHS provides detailed guidance on endometriosis treatment options.

How long can you stay on Utovlan tablets?

For period delay, Utovlan should not be used for more than 14 consecutive days. For longer-term conditions such as endometriosis or menorrhagia, your doctor will determine the appropriate duration of treatment. Extended use without medical supervision is not recommended and may carry additional risks.

Will my period be heavier than usual after stopping Utovlan?

Some women do notice that their period is slightly heavier or longer than usual after stopping Utovlan, as the uterine lining has had more time to build up. This is generally temporary and not a cause for concern. If bleeding is unusually heavy or prolonged, contact your GP for advice. You may also find our pain relief collection helpful for managing period discomfort.

Can I take Utovlan if I am on the contraceptive pill?

If you are already taking a combined oral contraceptive pill, taking Utovlan alongside it is generally not recommended — instead, your doctor may advise running pill packs back-to-back to delay your period. Always speak to your prescriber before combining hormonal medications, as interactions and risks need to be assessed individually.

What does the latest research say about norethisterone for period delay?

Norethisterone has been used clinically for period delay for many decades and remains a well-established option. Some research has highlighted a small increased risk of venous thromboembolism (blood clots) compared to the combined pill, which is why a thorough consultation is important before use. The NHS and BNF continue to recognise norethisterone as a clinically appropriate option for suitable patients.

How Should You Use Utovlan Tablets?

Utovlan tablets are taken orally with a glass of water. Always follow the instructions given by your prescriber or pharmacist, and read the patient information leaflet supplied with your pack before starting treatment.

Follow these steps for period delay use:

What Is the Correct Dose of Utovlan Tablets?

The dose of Utovlan varies depending on the condition being treated. Always use the dose prescribed or recommended by your healthcare professional. Do not adjust your dose without speaking to your doctor or pharmacist first.

When Is the Best Time to Use Utovlan Tablets?

For period delay, timing is everything. You must start taking Utovlan at least three days before your period is expected — starting later than this may not be effective. Plan ahead, particularly if you are delaying your period for a specific event such as a holiday or wedding.

Try to take each dose at the same times every day to maintain consistent hormone levels. If you take your tablets at irregular intervals, you may experience breakthrough bleeding, which can be frustrating and counterproductive.

How Long Can You Use Utovlan Tablets For?

For period delay, Utovlan should not be used for more than 14 consecutive days. This is the clinically recommended maximum for this indication. Using it for longer without medical supervision is not advised and may increase the risk of side effects.

For other conditions such as endometriosis or menorrhagia, your doctor will determine the appropriate length of treatment based on your individual circumstances. Long-term hormonal treatment should always be monitored by a healthcare professional. Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Utovlan Tablets?

Utovlan tablets are taken orally with a glass of water. Always follow the instructions given by your prescriber or pharmacist, and read the patient information leaflet supplied with your pack before starting treatment.

Follow these steps for period delay use:

What Is the Correct Dose of Utovlan Tablets?

The dose of Utovlan varies depending on the condition being treated. Always use the dose prescribed or recommended by your healthcare professional. Do not adjust your dose without speaking to your doctor or pharmacist first.

When Is the Best Time to Use Utovlan Tablets?

For period delay, timing is everything. You must start taking Utovlan at least three days before your period is expected — starting later than this may not be effective. Plan ahead, particularly if you are delaying your period for a specific event such as a holiday or wedding.

Try to take each dose at the same times every day to maintain consistent hormone levels. If you take your tablets at irregular intervals, you may experience breakthrough bleeding, which can be frustrating and counterproductive.

How Long Can You Use Utovlan Tablets For?

For period delay, Utovlan should not be used for more than 14 consecutive days. This is the clinically recommended maximum for this indication. Using it for longer without medical supervision is not advised and may increase the risk of side effects.

For other conditions such as endometriosis or menorrhagia, your doctor will determine the appropriate length of treatment based on your individual circumstances. Long-term hormonal treatment should always be monitored by a healthcare professional. Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Utovlan Tablets?

Most women tolerate Utovlan well, but like all medicines, it can cause side effects in some people. Common side effects are generally mild and tend to resolve once treatment is stopped. If you find them difficult to manage, speak to your pharmacist or GP.

  • Nausea or stomach discomfort
  • Headache
  • Breast tenderness or swelling
  • Mood changes, including low mood or irritability
  • Bloating or fluid retention
  • Irregular vaginal bleeding or spotting

What Are the Less Common Side Effects of Utovlan Tablets?

Less common side effects affect a smaller proportion of users but are still worth being aware of. These are not usually serious, but you should mention them to your doctor if they persist or worsen over time.

  • Acne or changes in skin condition
  • Decreased sex drive (libido)
  • Dizziness
  • Difficulty sleeping (insomnia)
  • Weight changes
  • Skin rash or urticaria (hives)
  • Depressive symptoms

What Are the Serious Side Effects of Utovlan Tablets?

Serious side effects are rare but require immediate medical attention. Norethisterone has been associated with a small increased risk of venous thromboembolism (blood clots), particularly in women with existing risk factors. Seek emergency help immediately if you experience any of the following:

  • Sudden chest pain or tightness
  • Shortness of breath or difficulty breathing
  • Swelling, redness, or pain in one leg
  • Severe or sudden headache, vision changes, or confusion
  • Signs of a severe allergic reaction: swelling of the face, lips, or throat, difficulty swallowing

What Should You Do If You Experience Side Effects of Utovlan?

If you experience mild side effects such as nausea or headache, taking your tablet with food may help. Staying well hydrated is also advisable. For mood-related side effects, keeping a symptom diary can help you and your doctor assess whether Utovlan is the right treatment for you.

You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve medicine safety monitoring across the UK.

Can Utovlan Interact With Other Medicines?

Yes — Utovlan can interact with several medicines, which may reduce its effectiveness or increase the risk of side effects. Always tell your prescriber about all medicines, supplements, and herbal remedies you are taking before starting Utovlan. Key interactions include enzyme-inducing drugs such as rifampicin, carbamazepine, phenytoin, and phenobarbital, as well as the herbal remedy St John's Wort. Utovlan may also affect the levels of ciclosporin in the blood and can alter the effects of anticoagulant medicines. If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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