Wegovy vs Saxenda UK: Compare Results & Price | Cured

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Wegovy vs Saxenda - Cheapest UK Price From £69.00

Compare Wegovy and Saxenda at the cheapest UK price from £69 with £20 off your first order using code WEIGHTLOSSNEW.

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£89.00 From £69.00 £10 discount using discount code Weightlossnew
LIVE PRICING

Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£99 £79.00

£19.75 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £99
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy vs Saxenda: Clinical Comparison for UK Patients

Choosing between wegovy vs saxenda uk comparison options requires understanding how semaglutide and liraglutide differ in clinical effectiveness, dosing frequency, and cost. At Cured Pharmacy, we provide transparent upfront pricing and expert guidance from UK-registered prescribers to help you make an informed decision about which weight loss injection may be right for you.

How Wegovy and Saxenda Work Differently

Both Wegovy (semaglutide) and Saxenda (liraglutide) are GLP-1 receptor agonists licensed by the MHRA for chronic weight management in the UK [1]. They work by mimicking the natural hormone GLP-1, which regulates appetite, slows gastric emptying, and helps control blood sugar levels. However, their molecular structures differ significantly, affecting how long they remain active in your body.

Wegovy is a once-weekly subcutaneous injection, whilst Saxenda requires daily administration [2]. This difference stems from semaglutide's longer half-life of approximately 7 days compared to liraglutide's 13 hours [1][2]. For many UK patients, the convenience of weekly dosing with Wegovy represents a significant practical advantage over daily injections, though individual preferences and clinical responses vary.

Clinical Trial Results: Weight Loss Outcomes

In the landmark STEP 1 trial, adults using Wegovy achieved an average body weight reduction of 14.9% over 68 weeks, compared to 2.4% with placebo [1]. Approximately 50% of participants lost at least 15% of their initial body weight, and nearly one-third lost 20% or more. These results represent some of the most significant weight loss outcomes achieved with pharmacological intervention in clinical trials.

The SCALE Obesity and Prediabetes trial evaluated Saxenda over 56 weeks, with participants achieving an average weight loss of 8.0% compared to 2.6% with placebo [2]. Whilst this demonstrates meaningful clinical benefit, the magnitude of weight reduction was notably lower than observed with semaglutide. Approximately 33% of Saxenda users lost at least 10% of their body weight during the trial period.

It's important to note that individual responses vary considerably, and clinical trial averages don't predict your personal outcome. Your UK prescriber will consider your medical history, weight loss goals, and any contraindications when recommending the most appropriate treatment.

Real-World Effectiveness in UK Practice

Beyond controlled trial environments, UK prescribers have observed that patient adherence often differs between weekly and daily injection regimens. Whilst both medications can produce meaningful weight loss when used as prescribed alongside lifestyle modifications, the practical convenience of Wegovy's weekly dosing may support better long-term adherence for some patients. However, others prefer the flexibility of adjusting daily doses or find daily injections easier to incorporate into their routine.

Wegovy vs Saxenda UK Comparison: Dosing and Administration

Wegovy follows a structured dose escalation protocol over 16-20 weeks, starting at 0.25 mg weekly and gradually increasing to the maintenance dose of 2.4 mg weekly [3]. This gradual titration helps minimise gastrointestinal side effects whilst your body adjusts to the medication. The pre-filled FlexTouch pens are designed for subcutaneous injection into the abdomen, thigh, or upper arm.

Saxenda begins at 0.6 mg daily, increasing by 0.6 mg increments each week until reaching the maintenance dose of 3.0 mg daily [4]. The daily injection requirement means you'll use approximately 30 injections per month compared to 4-5 with Wegovy. Both medications should be stored in the refrigerator before first use, though in-use pens can be kept at room temperature for specified periods.

Your UK prescriber will provide detailed injection technique guidance during your clinical consultation. Proper injection site rotation and technique are essential for both medications to optimise absorption and minimise injection site reactions.

Practical Considerations for UK Patients

When comparing wegovy vs saxenda uk options, consider your lifestyle and preferences. Weekly injections may suit patients who travel frequently or prefer fewer injection events, whilst daily dosing offers more frequent opportunities to adjust timing around your schedule. Both require consistent use alongside reduced-calorie diet and increased physical activity for optimal results, as recommended by NICE guidelines for weight management [5].

Feature Wegovy (Semaglutide) Saxenda (Liraglutide)
Active Ingredient Semaglutide Liraglutide
Injection Frequency Once weekly Once daily
Maintenance Dose 2.4 mg weekly 3.0 mg daily
Average Weight Loss (Clinical Trials) 14.9% over 68 weeks 8.0% over 56 weeks
Starting Price at Cured Pharmacy From £69.00 From £69.00
Dose Escalation Period 16-20 weeks 4-5 weeks
Half-Life ~7 days ~13 hours
Storage After First Use Room temperature up to 28 days Room temperature up to 30 days

Side Effects and Safety Profile Comparison

The most common side effects for both Wegovy and Saxenda are gastrointestinal, including nausea, diarrhoea, vomiting, constipation, and abdominal pain [1][2]. These effects typically occur during dose escalation and often diminish as your body adjusts. In clinical trials, nausea affected approximately 44% of Wegovy users and 39% of Saxenda users, though most cases were mild to moderate in severity.

Both medications carry a boxed warning regarding thyroid C-cell tumours observed in rodent studies, though the relevance to humans remains uncertain [3][4]. They are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Your UK prescriber will screen for these contraindications during your clinical assessment.

Serious but less common risks include pancreatitis, gallbladder disease, and acute kidney injury, particularly in patients who experience severe vomiting or diarrhoea leading to dehydration [5]. If you experience persistent severe abdominal pain, you should contact your healthcare provider immediately. Both medications may also affect heart rate slightly, and regular monitoring is recommended for patients with cardiovascular conditions.

Transparent Pricing: No Hidden Consultation Fees

At Cured Pharmacy, Wegovy starts from £79.00 with completely transparent pricing displayed before your free clinical consultation [6]. Unlike some UK pharmacy services that add consultation fees, prescription charges, or delivery costs at checkout, our upfront pricing model ensures you know exactly what you'll pay from the start. This commitment to transparency reflects our superintendent pharmacist Tarun Kumar's dedication to accessible, honest healthcare.

The total cost of your weight loss treatment depends on your prescribed dose and treatment duration, which your UK prescriber determines based on your clinical assessment and response to therapy. Both medications require ongoing prescription renewal through regular clinical reviews to monitor your progress, adjust dosing if needed, and ensure continued safety and appropriateness of treatment.

We guarantee the lowest prices in the UK for genuine, MHRA-licensed weight loss medications. All prescriptions are fulfilled by our GPhC-registered pharmacy (9012511) with discreet packaging and reliable delivery. There are no hidden fees, membership charges, or surprise costs — just transparent, competitive pricing for quality pharmaceutical care.

What's Included in Your Treatment Package

Your treatment includes a comprehensive online clinical assessment completed in under 3 minutes, review and prescribing by a UK-registered prescriber, dispensing by our qualified pharmacy team, and discreet home delivery. Follow-up consultations for prescription renewals are also provided at no additional consultation fee, ensuring continuity of care throughout your weight loss journey.

Starting Your Weight Loss Treatment at Cured Pharmacy

Beginning treatment is straightforward: complete our online clinical questionnaire, which takes under 3 minutes and covers your medical history, current medications, weight loss goals, and any contraindications. A UK-registered prescriber reviews your assessment, typically within 24 hours, and determines whether Wegovy, Saxenda, or an alternative treatment is clinically appropriate for you.

If approved, your prescription is sent to our GPhC-registered pharmacy where our team, led by superintendent pharmacist Tarun Kumar (GPhC 2233073), dispenses your medication. We use 100% discreet packaging for all deliveries, with no external indication of contents. Most orders are dispatched within 1-2 working days via tracked courier.

Weight loss medications work best as part of a comprehensive approach including dietary changes and increased physical activity. Your prescriber may provide guidance on lifestyle modifications, and we encourage working with your NHS GP or practice nurse for ongoing weight management support. Regular monitoring of your progress, side effects, and overall health is essential for safe, effective treatment.

If you have questions about which medication may be right for you, our pharmacy team is available on (+44) 116 4646009 during business hours. However, only a qualified prescriber can determine clinical suitability through a proper assessment — we cannot provide prescribing advice over the phone.

Scientific References

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183
  2. Pi-Sunyer, X., Astrup, A., Fujioka, K., et al. (2015). A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal of Medicine, 373(1), 11–22. https://doi.org/10.1056/NEJMoa1411892
  3. Novo Nordisk. (2023). Wegovy 2.4 mg Solution for Injection in Pre-filled Pen: Summary of Product Characteristics. Electronic Medicines Compendium. Retrieved from https://www.medicines.org.uk/emc/product/13799
  4. Novo Nordisk. (2023). Saxenda 6 mg/ml Solution for Injection in Pre-filled Pen: Summary of Product Characteristics. Electronic Medicines Compendium. Retrieved from https://www.medicines.org.uk/emc/product/2313
  5. National Institute for Health and Care Excellence. (2023). Obesity: Identification, Assessment and Management (CG189). NICE Guidelines. Retrieved from https://www.nice.org.uk/guidance/cg189
  6. Medicines and Healthcare products Regulatory Agency. (2023). Semaglutide (Wegovy) and Liraglutide (Saxenda): Drug Safety Update. GOV.UK. Retrieved from https://www.gov.uk/drug-safety-update

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Individual results may vary, and weight loss outcomes depend on multiple factors including adherence to treatment, dietary modifications, and physical activity levels.

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Faq

Which is better for weight loss: Wegovy or Saxenda?
Clinical trial data shows Wegovy (semaglutide) produced greater average weight loss (14.9%) compared to Saxenda (8.0%), though individual responses vary. Your UK prescriber will recommend the most appropriate option based on your medical history, preferences, and clinical circumstances.
Can I switch from Saxenda to Wegovy?
Yes, switching between these medications is possible under prescriber supervision. Your UK clinician will determine appropriate timing and dosing for the transition, typically allowing a washout period and starting Wegovy at the initial 0.25 mg dose despite previous liraglutide use.
How much does wegovy vs saxenda cost in the UK?
At Cured Pharmacy, Wegovy starts from £79.00 and Saxenda from £79.00, with transparent pricing shown before your free consultation. Final cost depends on your prescribed dose and treatment duration, determined by your UK prescriber during clinical assessment.
Do I need a prescription for Wegovy or Saxenda?
Yes, both are prescription-only medications in the UK and require clinical assessment by a UK-registered prescriber. Cured Pharmacy provides a free online consultation as part of our service, with prescribing decisions made by qualified clinicians based on your medical suitability.
How quickly do Wegovy and Saxenda work?
Most patients begin noticing appetite reduction within the first few weeks, though significant weight loss typically accumulates over months of consistent use alongside lifestyle modifications. Clinical trials measured outcomes at 56-68 weeks, reflecting the long-term nature of weight management treatment.
Can I use Wegovy or Saxenda if I have diabetes?
Both medications can be used in patients with type 2 diabetes, though different formulations (Ozempic, Victoza) are specifically licensed for diabetes management. Your UK prescriber will consider your diabetes status, current medications, and HbA1c levels when determining the most appropriate treatment option.
What happens if I miss a dose of Wegovy or Saxenda?
For Wegovy, if you miss a dose and it's been less than 5 days, take it as soon as possible; if more than 5 days have passed, skip that dose and resume your regular schedule. For Saxenda's daily dosing, resume your normal dose the next day without doubling up.
Are there any foods I should avoid whilst taking Wegovy or Saxenda?
No specific foods are prohibited, though high-fat, high-sugar, and large-portion meals may worsen gastrointestinal side effects. A reduced-calorie diet with balanced nutrition supports both medication effectiveness and overall health, as recommended in NICE weight management guidelines.
Which is cheaper in the UK - Wegovy or Saxenda?
Wegovy is typically cheaper than Saxenda when comparing cost per month of treatment. At Cured Pharmacy, Wegovy starts from £69 with £20 off your first order using code WEIGHTLOSSNEW, making it the most cost-effective weight loss injection option available in the UK.
Can I switch from Saxenda to Wegovy with Cured Pharmacy?
Yes, you can switch from Saxenda to Wegovy through Cured Pharmacy. Our UK-registered prescribers will review your medical history and current treatment during your online consultation to ensure a safe transition. Many patients switch to Wegovy due to its once-weekly dosing compared to Saxenda's daily injections.
How do Wegovy and Saxenda prices compare per dose?
Wegovy requires one injection weekly while Saxenda needs daily injections, making Wegovy more economical overall. Cured Pharmacy offers Wegovy from £69 per pen, covering four weekly doses, whereas Saxenda requires purchasing multiple pens monthly for daily use.
Is Wegovy or Saxenda better for weight loss results?
Clinical studies show Wegovy typically delivers greater average weight loss than Saxenda, with patients losing around 15% of body weight versus 8% with Saxenda. Cured Pharmacy's UK prescribers can help determine which medication suits your individual weight loss goals during your consultation.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Last reviewed: 17 July 2026