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Understanding Tadalafil Pack Sizes: Strengths, Pricing and How to Order Safely
Published: 8 November 2026
Tadalafil pack sizes vary by strength and quantity, giving you flexibility to choose the option that best suits your needs and budget. Tadalafil is the generic version of Cialis, a prescription medicine used to treat erectile dysfunction (ED) in men [1]. Available in 10mg and 20mg tablets, tadalafil can be taken on-demand before sexual activity, with effects lasting up to 36 hours, or as a lower daily dose (2.5mg or 5mg) for continuous support [4].
Key takeaways
- Tadalafil is available in 10mg and 20mg strengths for on-demand use, lasting up to 36 hours.
- Generic tadalafil starts from £7.95, or £6.36 for your first order with code Ednew.
- Larger pack sizes offer better value per tablet if you use tadalafil regularly.
- All tadalafil orders require a prescription following an online consultation with a UK prescriber.
- Never take tadalafil with nitrates, nicorandil, riociguat, or other ED medicines.
What Tadalafil Pack Sizes Are Available in the UK?
Tadalafil is supplied in two main strengths for on-demand use: 10mg and 20mg tablets [4]. The 10mg dose is typically the recommended starting strength, while 20mg may be prescribed if the lower dose is not effective or if your prescriber considers it more suitable based on your individual circumstances. Pack sizes commonly range from 4 tablets up to 28 or more, allowing you to order a quantity that matches how often you plan to use the treatment.
At Cured Pharmacy, generic tadalafil is available from £7.95 per pack (or £6.36 for your first order with code Ednew). Branded Cialis is also stocked at £12.00 (£9.60 with code Ednew), and Teva-manufactured tadalafil 20mg is priced at £9.99 (£7.99 with code Ednew). Avarante, another tadalafil brand in 10mg strength, costs £11.49 (£9.19 with code Ednew). All tadalafil products require a prescription following an online consultation with a UK-registered prescriber, who will review your medical history and current medicines to ensure the treatment is safe and appropriate for you [2].
Choosing the right pack size depends on how frequently you anticipate needing the medication. Smaller packs are ideal if you are trying tadalafil for the first time or use it occasionally, while larger packs offer better value if you use the treatment regularly. Your prescriber can advise on the most suitable strength and quantity during your consultation.
How Do Tadalafil Strengths Compare?
Tadalafil is licensed in the UK in four strengths: 2.5mg and 5mg for daily use, and 10mg and 20mg for on-demand use [4]. The on-demand doses are taken at least 30 minutes before sexual activity, and the effect can last up to 36 hours, which is why tadalafil is sometimes called the 'weekend pill'. This long duration means you do not need to time the tablet as precisely as with some other ED treatments, offering greater spontaneity.
The 10mg strength is the usual starting dose for most men. If this proves effective and well-tolerated, it may be continued; if not, the prescriber may increase the dose to 20mg or, conversely, reduce it to 5mg if side effects occur [4]. Daily tadalafil (2.5mg or 5mg) is an alternative regimen for men who prefer not to plan ahead and want continuous support. Daily dosing is taken at the same time each day, regardless of sexual activity, and may be suitable if you are sexually active more than twice a week.
Your prescriber will consider factors such as your overall health, other medications, and how you respond to treatment when recommending a strength. It is important never to take more than one on-demand dose in 24 hours, and not to combine tadalafil with other ED medicines or with nitrates, nicorandil, riociguat, or recreational drugs known as 'poppers', as these combinations can cause a dangerous drop in blood pressure [4].
On-Demand vs Daily Tadalafil
On-demand tadalafil (10mg or 20mg) is taken as needed before sexual activity and suits men who do not require daily treatment. Daily tadalafil (2.5mg or 5mg) is taken every day and may be preferred by those who value spontaneity and are sexually active frequently. Both regimens are effective, and the choice depends on your lifestyle and preferences, which you can discuss during your online consultation.
At a glance
What Affects the Price of Tadalafil Pack Sizes?
Several factors influence the cost of tadalafil. Generic versions are typically more affordable than branded Cialis because they do not carry the research and marketing costs of the original product, yet they contain the same active ingredient and meet the same UK regulatory standards [4]. The strength of the tablet also plays a role: higher-strength tablets (20mg) may cost slightly more per tablet than 10mg, though the difference is often modest.
Pack size is another key factor. Larger packs usually offer a lower cost per tablet, making them more economical if you use tadalafil regularly. For example, buying a 28-tablet pack works out cheaper per dose than purchasing multiple smaller packs over time. Manufacturer can also affect price: Teva and Avarante are both reputable suppliers, and their products are priced competitively alongside unbranded generics.
At Cured Pharmacy, first-time customers receive 20% off with code Ednew, reducing the price of generic tadalafil to £6.36 and branded Cialis to £9.60. This discount applies across all pack sizes and strengths, helping you try the treatment at a lower cost. Prescription fees are included in the price, and delivery is discreet and fast, with no hidden charges. Because tadalafil is a prescription-only medicine, every order requires completion of an online consultation, which is reviewed by a UK prescriber to ensure the treatment is safe for you [2].
How to Order Tadalafil Pack Sizes Safely Online
Ordering tadalafil online from a registered UK pharmacy is straightforward and confidential. At Cured Pharmacy (GPhC 9012511), you start by selecting the tadalafil product and pack size that suits your needs. You will then complete a short online consultation form, which asks about your medical history, current medications, and any underlying health conditions. This information is essential for the prescriber to assess whether tadalafil is safe and appropriate for you [2].
A UK-registered prescriber reviews every consultation. They will check for contraindications, such as use of nitrates, nicorandil, riociguat, or other PDE5 inhibitors, and consider any interactions with medicines you are already taking, including alpha-blockers or potent CYP3A4 inhibitors like ritonavir or ketoconazole [4]. If the prescriber approves your request, the prescription is sent to the pharmacy, and your order is dispensed and dispatched in discreet, unbranded packaging. If tadalafil is not suitable, the prescriber will explain why and may suggest an alternative treatment or advise you to see your GP.
It is important to use only registered online pharmacies. You can verify Cured Pharmacy's registration on the General Pharmaceutical Council website. Avoid websites that offer prescription medicines without a consultation, as these are operating illegally and may supply counterfeit or unsafe products. Genuine tadalafil requires a prescription for good reason: your safety depends on a qualified healthcare professional reviewing your individual circumstances before you start treatment.
What Happens During the Online Consultation?
The online consultation takes just a few minutes. You will answer questions about your general health, any heart or blood pressure problems, current medications, and whether you have had any previous reactions to ED treatments. The prescriber uses this information to decide if tadalafil is safe for you and, if so, which strength and pack size to recommend. If you have any questions, you can contact the pharmacy team for advice before or after placing your order.
Choose Your Pack Size Wisely
If you are new to tadalafil, start with a smaller pack to see how you respond. Once you know it works for you, larger packs offer better value per tablet and are more convenient for regular use.
Comparing Tadalafil Pack Sizes with Other ED Treatments
Tadalafil is one of several PDE5 inhibitors licensed in the UK for erectile dysfunction. Sildenafil (generic Viagra) is the most widely known alternative, available in 25mg, 50mg, and 100mg strengths. Sildenafil is taken about one hour before sexual activity and lasts for around four to six hours [3]. At Cured Pharmacy, generic sildenafil starts from £0.45 per tablet (£0.36 with code Ednew), making it a very cost-effective option, though its shorter duration means it requires more precise timing than tadalafil.
Vardenafil (generic Levitra) is another PDE5 inhibitor, available in 5mg, 10mg, and 20mg strengths. It is taken 25 to 60 minutes before sex and has a similar duration to sildenafil [5]. Vardenafil is priced at £16.95 (£13.56 with code Ednew). Avanafil (Spedra) is the newest PDE5 inhibitor, with a faster onset of action—around 15 to 30 minutes—and is available in 50mg, 100mg, and 200mg strengths [6]. Spedra costs £20.95 (£16.76 with code Ednew) and may suit men who value a rapid effect.
The choice between these treatments depends on your preferences and lifestyle. Tadalafil's long duration (up to 36 hours) is ideal if you want flexibility and spontaneity, while sildenafil's lower cost and shorter action may be preferable if you plan ahead and use treatment less frequently. Your prescriber can help you weigh the options during your consultation, taking into account your medical history and any other medicines you take [2].
Common Questions About Tadalafil Pack Sizes and Dosing
Many men wonder whether they should start with a smaller or larger pack. If you are new to tadalafil, a smaller pack (e.g. 4 or 8 tablets) allows you to try the treatment and see how you respond before committing to a larger quantity. If you find tadalafil effective and well-tolerated, ordering a larger pack on your next purchase will reduce the cost per tablet. Your prescriber may also adjust the strength after your first pack if needed.
Another common question is whether higher-strength tablets can be split. Tadalafil tablets are not scored and are not designed to be divided. If a lower dose is required, you should be prescribed the appropriate strength rather than splitting a higher-strength tablet. This ensures accurate dosing and avoids the risk of uneven splitting. If you experience side effects on 10mg or 20mg, speak to your prescriber, who may recommend a lower dose or an alternative treatment.
Some men ask whether they can take tadalafil every day. Daily tadalafil (2.5mg or 5mg) is licensed for this purpose and is taken at the same time each day, regardless of sexual activity [4]. On-demand tadalafil (10mg or 20mg) should not be taken more than once in 24 hours. Mixing different ED treatments or taking tadalafil with nitrates, nicorandil, riociguat, or 'poppers' is dangerous and must be avoided. Always declare all your current medicines during the consultation so the prescriber can check for interactions.
Can I Switch Between Tadalafil Pack Sizes or Strengths?
Yes, you can switch pack sizes or strengths, but any change in dose must be approved by a prescriber. If you find that 10mg is not effective, your prescriber may increase you to 20mg. Conversely, if you experience side effects, a lower dose may be suggested. You can also change pack size based on how often you use the treatment. Simply complete a new consultation when you reorder, and the prescriber will review your request.
When to get urgent help
- Erection lasting more than 4 hours (priapism) – go to A&E immediately.
- Sudden loss of vision or hearing – stop taking tadalafil and seek urgent medical help.
- Chest pain during or after sex – stop activity, do not take more tadalafil, and call 999 if pain persists.
- Severe dizziness or fainting after taking tadalafil – lie down and seek medical advice urgently.
- Allergic reaction (rash, swelling of face or throat, difficulty breathing) – call 999 immediately.
Call 999 or go to A&E in an emergency, or contact NHS 111 for urgent advice.
Scientific References
- NHS. (n.d.). Erectile dysfunction (impotence). NHS website. https://www.nhs.uk/conditions/erection-problems-erectile-dysfunction/ [accessed 8 November 2026]
- National Institute for Health and Care Excellence. (n.d.). Erectile dysfunction. Clinical Knowledge Summaries. https://cks.nice.org.uk/topics/erectile-dysfunction/ [accessed 8 November 2026]
- Joint Formulary Committee. (n.d.). Sildenafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/sildenafil/ [accessed 8 November 2026]
- Joint Formulary Committee. (n.d.). Tadalafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/tadalafil/ [accessed 8 November 2026]
- Joint Formulary Committee. (n.d.). Vardenafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/vardenafil/ [accessed 8 November 2026]
- Joint Formulary Committee. (n.d.). Avanafil. British National Formulary. NICE. https://bnf.nice.org.uk/drugs/avanafil/ [accessed 8 November 2026]
Information on this page is for educational purposes only and is not medical advice. Prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting or changing any medication.
Your Questions Answered
Can't find your answer? Our UK pharmacists review every consultation and can help.
What is the difference between 10mg and 20mg tadalafil?
The 10mg dose is the usual starting strength for most men, while 20mg is a higher dose that may be prescribed if 10mg is not effective. Both last up to 36 hours and are taken on-demand at least 30 minutes before sexual activity.
Can I buy tadalafil in larger pack sizes to save money?
Yes, larger packs typically offer a lower cost per tablet. At Cured Pharmacy, you can choose the pack size that suits your needs, and all orders include 20% off your first purchase with code Ednew.
Is generic tadalafil the same as branded Cialis?
Yes, generic tadalafil contains the same active ingredient and meets the same UK regulatory standards as branded Cialis. The main difference is price: generics are more affordable because they do not carry the branding costs.
How long does a pack of tadalafil last?
It depends on how often you use it. If you take tadalafil once a week, a 4-tablet pack lasts about a month, while a 28-tablet pack lasts around seven months. On-demand tadalafil should not be taken more than once in 24 hours.
Do I need a prescription for every tadalafil order?
Yes, tadalafil is a prescription-only medicine. Each order requires an online consultation reviewed by a UK prescriber, who will check that the treatment remains safe and appropriate for you.
Can I switch from sildenafil to tadalafil?
Yes, many men switch between ED treatments to find the one that suits them best. You will need to complete a new consultation so the prescriber can review your medical history and ensure tadalafil is safe for you.
What if 10mg tadalafil does not work for me?
If 10mg is not effective, your prescriber may increase the dose to 20mg or suggest trying a different PDE5 inhibitor. Contact the pharmacy or complete a new consultation to discuss your options.
Are there any medicines I cannot take with tadalafil?
Yes, tadalafil must not be taken with nitrates, nicorandil, riociguat, 'poppers', or another PDE5 inhibitor, as these combinations can cause a dangerous drop in blood pressure. Always declare all your current medicines during the consultation.
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Medically reviewed by
Tarun Kumar, Superintendent Pharmacist (GPhC 2233073)