Tadalafil 5mg Cheapest UK Price - From £7.99 | Cured

Clinically Proven UK Registered Pharmacy

Tadalafil 5mg - Cheapest UK Price From £7.99

Get tadalafil 5mg at the cheapest UK price from £7.99 with 20% off first order using code Ednew.

UK-registered clinical team
Confidential and secure
No GP visit needed
Fast and discreet delivery
Start Your Free Consultation

Takes less than 2 minutes to complete 100% online

Ednew 20% off for new customers
Genuine Products
UK-licensed only
Fast Delivery
Next-day available
Expert Advice
UK pharmacists
Man using Cured Pharmacy online consultation for erectile dysfunction treatment
£9.99 From £7.99 20% discount using discount code Ednew
LIVE PRICING

Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Sildenafil - UK-licensed prescription Treatment
Treatment

Sildenafil

From £0.45

Future orders save 5%
Start Assessment
Tadalafil - UK-licensed prescription Treatment
Treatment

Tadalafil

From £9.99

Future orders save 5%
Start Assessment
Sildenafil Eropid - UK-licensed prescription Treatment
Treatment

Sildenafil Eropid

From £8.99

Future orders save 5%
Start Assessment
Tadalafil (Teva) - UK-licensed prescription Treatment
Treatment

Tadalafil (Teva)

From £9.99

Future orders save 5%
Start Assessment
Avarante Tablets Tadalafil Tablets 10mg - UK-licensed prescription Treatment
Treatment

Avarante Tablets Tadalafil Tablets 10mg

From £11.49

Future orders save 5%
Start Assessment
Viagra Connect 50mg - UK-licensed prescription Treatment
Treatment

Viagra Connect 50mg

From £11.49

Future orders save 5%
Start Assessment

Tadalafil 5mg: Daily Treatment for Erectile Dysfunction

Tadalafil 5mg is a low-dose daily treatment for erectile dysfunction (ED) that provides continuous support rather than on-demand dosing. Unlike higher-strength tadalafil taken before sexual activity, the 5mg daily dose maintains steady therapeutic levels, allowing for spontaneity without planning ahead. This approach suits men who prefer not to time medication around intimacy and has demonstrated consistent efficacy in clinical trials [1].

How Tadalafil 5mg Works for Daily ED Management

Tadalafil 5mg belongs to the phosphodiesterase type 5 (PDE5) inhibitor class and works by increasing blood flow to the penis during sexual stimulation. When taken daily, it maintains a constant level of the active ingredient in your system, which means you don't need to plan doses around sexual activity [1]. This differs significantly from higher on-demand doses (10mg or 20mg) that are taken 30 minutes to 12 hours before intercourse.

The daily regimen is particularly effective for men who engage in sexual activity more than twice weekly, as it eliminates the need to anticipate timing. Clinical studies show that tadalafil 5mg taken once daily significantly improved erectile function scores compared to placebo, with effects maintained throughout the 24-hour dosing interval [2]. The medication reaches steady-state plasma concentrations after approximately five days of once-daily dosing, providing consistent therapeutic benefit.

Because tadalafil has a half-life of 17.5 hours—considerably longer than sildenafil—the 5mg daily dose maintains effective drug levels without accumulation to unsafe levels [3]. This pharmacokinetic profile makes it uniquely suited for continuous daily use, subject to prescriber assessment and approval based on your individual health profile.

Tadalafil 5mg Dosing: What to Expect from Daily Treatment

The standard tadalafil 5mg daily dose is one tablet taken at approximately the same time each day, regardless of when sexual activity is planned. This consistency is crucial for maintaining therapeutic drug levels. Most men begin noticing improvement within the first week, though optimal effects typically emerge after two to four weeks of continuous use [2].

Your prescriber may adjust your dose based on efficacy and tolerability. Some men with milder ED or those taking certain medications (such as alpha-blockers or potent CYP3A4 inhibitors) may be started on 2.5mg daily instead. Conversely, if 5mg proves insufficient after adequate trial, your clinician might increase the dose to 10mg or 20mg for on-demand use rather than daily dosing.

Switching from On-Demand to Tadalafil 5mg Daily

Men currently using on-demand tadalafil (10mg or 20mg) or sildenafil can transition to tadalafil 5mg daily if they prefer spontaneity over planned dosing. The switch is straightforward: simply begin taking 5mg once daily, ideally at a consistent time. There is no need for a washout period, though your prescriber will review your current medication regimen to ensure no contraindications exist [3].

Clinical evidence supports this transition, with studies demonstrating that men switching from on-demand PDE5 inhibitors to daily tadalafil 5mg report high satisfaction rates, particularly valuing the freedom from timing constraints and the psychological benefit of not needing to plan intimacy around medication [4].

Benefits of Tadalafil 5mg Over Higher On-Demand Doses

The primary advantage of tadalafil 5mg daily dosing is spontaneity. You are ready for sexual activity at any time without needing to take a pill beforehand, which many men find reduces performance anxiety and improves overall sexual confidence. This psychological benefit is frequently cited in patient-reported outcomes from clinical trials [4].

Daily tadalafil 5mg also offers benefits for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). The same 5mg dose is licensed in the UK for treating both ED and BPH symptoms simultaneously, providing dual therapeutic action that on-demand higher doses do not address as effectively [1]. Men experiencing both conditions may find particular value in this dual benefit.

From a practical standpoint, the lower daily dose typically produces fewer side effects than higher on-demand doses. Headache, flushing, and dyspepsia—the most common adverse effects—tend to be milder and less frequent with 5mg daily compared to 20mg on-demand use [2]. This improved tolerability profile contributes to better long-term adherence.

Treatment Type Frequency Starting Price
Tadalafil 5mg PDE5 Inhibitor Daily £9.99
Tadalafil 10mg/20mg PDE5 Inhibitor On-demand £9.99
Sildenafil 50mg/100mg PDE5 Inhibitor On-demand £0.45
Cialis (Brand Tadalafil) PDE5 Inhibitor On-demand/Daily £53.00
Viagra Connect 50mg PDE5 Inhibitor On-demand £11.49

Tadalafil 5mg Side Effects and Safety Considerations

Common side effects of tadalafil 5mg include headache (reported in approximately 3-4% of daily users), dyspepsia, back pain, nasal congestion, and flushing. These effects are generally mild and diminish with continued use as your body adjusts to the medication [2]. Serious adverse events are rare but include sudden vision or hearing loss, priapism (erection lasting over four hours), and cardiovascular events in susceptible individuals.

Tadalafil 5mg is contraindicated in men taking nitrates (for angina) or riociguat (for pulmonary hypertension) due to the risk of severe hypotension. It should be used cautiously in men with cardiovascular disease, and your prescriber will assess your fitness for sexual activity as part of the consultation process. Men with severe hepatic impairment or end-stage renal disease require dose adjustments or may not be suitable candidates [3].

Drug Interactions with Tadalafil 5mg Daily

Tadalafil 5mg interacts with several medication classes. Alpha-blockers (used for hypertension or BPH) can cause additive blood pressure lowering, so your prescriber may adjust timing or doses. Potent CYP3A4 inhibitors such as ketoconazole, ritonavir, and clarithromycin increase tadalafil plasma levels, potentially necessitating a dose reduction to 2.5mg daily [3].

Grapefruit juice should be consumed in moderation, as it inhibits CYP3A4 and may increase tadalafil exposure. Alcohol does not have a clinically significant interaction with tadalafil 5mg, though excessive alcohol consumption can independently impair erectile function and should be moderated. Always disclose all medications and supplements during your online consultation to ensure safe prescribing.

Buying Tadalafil 5mg Online: UK Prescription Requirements

Tadalafil 5mg is a prescription-only medicine (POM) in the UK, meaning it legally requires a consultation with a registered prescriber before supply. At Cured Pharmacy, our UK-registered clinical team conducts a free online assessment that takes under three minutes, reviewing your medical history, current medications, and cardiovascular health to determine suitability [5].

Once approved, your tadalafil 5mg prescription is dispensed by our GPhC-registered pharmacy (registration number 9012511) under the supervision of superintendent pharmacist Tarun Kumar (GPhC 2233073). We supply only genuine UK-licensed medicines sourced from reputable wholesalers, ensuring quality and authenticity. Prices start from £7.99, with 20% off your first order using code Ednew, making it the cheapest UK price available for this daily treatment.

Discreet packaging is standard for all orders, with next-day delivery available across the UK. Your medication arrives in plain, unmarked packaging with no indication of contents, respecting your privacy throughout the process. All transactions are secure, and your personal health information is handled in strict accordance with UK GDPR and GPhC confidentiality standards.

Tadalafil 5mg vs 10mg and 20mg: Choosing the Right Strength

Tadalafil 5mg is specifically formulated for daily use, while 10mg and 20mg strengths are intended for on-demand dosing. The choice between daily low-dose and on-demand higher-dose depends on your sexual activity frequency, lifestyle preferences, and response to treatment. Men who engage in sexual activity twice weekly or more often typically benefit most from the daily 5mg regimen [4].

Clinical trials directly comparing daily tadalafil 5mg to on-demand 10mg found comparable efficacy in improving erectile function, with the daily regimen offering superior spontaneity and patient satisfaction scores [2]. However, some men with more severe ED or those who prefer dosing only when needed may achieve better results with the higher on-demand strengths.

Your prescriber will recommend the most appropriate strength based on your individual circumstances, including ED severity, comorbid conditions (such as BPH), and personal preference. It is possible to trial different regimens under clinical supervision to identify the optimal approach for your needs. Switching between strengths is straightforward and does not require a washout period, subject to prescriber guidance.

Cost Comparison: Daily vs On-Demand Tadalafil

When comparing costs, daily tadalafil 5mg requires 30 tablets per month, whereas on-demand dosing uses only the number of tablets corresponding to sexual activity frequency. For men engaging in intimacy twice weekly, on-demand dosing (8-10 tablets monthly) may be more economical. However, for those with higher activity frequency or who value spontaneity, the daily regimen offers better value and convenience despite the higher monthly tablet count.

At Cured Pharmacy, tadalafil 5mg is priced competitively at £7.99, with transparent upfront pricing and no hidden consultation fees. Our lowest price guarantee ensures you receive the cheapest UK price for genuine licensed tadalafil, with the added benefit of 20% off your first order using code Ednew. This pricing structure makes daily treatment accessible and affordable for long-term ED management.

Scientific References

  1. Porst, H., Giuliano, F., Glina, S., Ralph, D., Casabé, A. R., Elion-Mboussa, A., & Sorsaburu, S. (2006). Evaluation of the efficacy and safety of once-a-day dosing of tadalafil 5mg and 10mg in the treatment of erectile dysfunction: results of a multicenter, randomized, double-blind, placebo-controlled trial. European Urology, 50(2), 351-359.
  2. Rajfer, J., Aliotta, P. J., Steidle, C. P., Fitch, W. P., Zhao, Y., & Yu, A. (2007). Tadalafil dosed once a day in men with erectile dysfunction: a randomized, double-blind, placebo-controlled study in the US. International Journal of Impotence Research, 19(1), 95-103.
  3. Forgue, S. T., Patterson, B. E., Bedding, A. W., Payne, C. D., Phillips, D. L., Wrishko, R. E., & Mitchell, M. I. (2006). Tadalafil pharmacokinetics in healthy subjects. British Journal of Clinical Pharmacology, 61(3), 280-288.
  4. Hatzichristou, D., Gambla, M., Rubio-Aurioles, E., Buvat, J., Brock, G. B., Spera, G., & Rose, L. (2008). Efficacy of tadalafil once daily in men with diabetes mellitus and erectile dysfunction. Diabetic Medicine, 25(2), 138-146.
  5. Medicines and Healthcare products Regulatory Agency. (2023). Tadalafil 5mg film-coated tablets: Summary of Product Characteristics. MHRA UK Public Assessment Report.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

How it Works?

Select from our recommended UK-licensed medications.

1

Choose your treatment

Step 1: Choose your treatment from Cured Pharmacy

Select safe UK treatments. Quick answers.

2

Answer quick questions

Step 2: Answer quick consultation questions

We will deliver direct to you as quickly as tomorrow.

3

Get it delivered fast

Step 3: Fast discreet delivery to your door

Start Your Assessment For Erectile Dysfunction

Start your journey to better health today.

  • Reviewed by UK-based prescribers
  • Takes under 3 minutes
  • Discreet Packaging

Start Your Journey To Better Health Today

Once you complete a short online assessment you will be able to choose your preferred treatment from safe medically approved options tailored to you.

Start My Assessment

Returning Customer?

Log in to Your Account

Faq

How long does tadalafil 5mg take to work when starting daily treatment?
Most men notice improvement within the first week of daily tadalafil 5mg, though optimal effects typically emerge after two to four weeks of continuous use as steady-state drug levels are established.
Can I take tadalafil 5mg every other day instead of daily?
Tadalafil 5mg is licensed for once-daily use to maintain consistent therapeutic levels. Taking it every other day may reduce efficacy and is not a recommended dosing schedule; consult your prescriber if daily dosing is inconvenient.
Is tadalafil 5mg effective for severe erectile dysfunction?
Tadalafil 5mg daily is effective for mild to moderate ED, but men with severe ED may require higher on-demand doses (10mg or 20mg) for optimal results, subject to prescriber assessment.
Can I drink alcohol while taking tadalafil 5mg daily?
Moderate alcohol consumption does not significantly interact with tadalafil 5mg, though excessive drinking can independently impair erectile function and should be limited for best treatment outcomes.
Does tadalafil 5mg help with prostate symptoms as well as ED?
Yes, tadalafil 5mg is licensed in the UK for treating both erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH), offering dual therapeutic benefit.
What should I do if I miss a dose of tadalafil 5mg?
If you miss a daily tadalafil 5mg dose, take it as soon as you remember, then resume your regular schedule the next day. Do not double the dose to make up for a missed tablet.
Can I switch from sildenafil to tadalafil 5mg daily?
Yes, switching from sildenafil to tadalafil 5mg daily is straightforward and requires no washout period. Your prescriber will review your response to sildenafil and confirm suitability for daily tadalafil during your consultation.
Is tadalafil 5mg safe for long-term daily use?
Clinical trials demonstrate that tadalafil 5mg is safe and well-tolerated for long-term daily use, with adverse effects remaining mild and consistent over extended treatment periods, subject to ongoing prescriber review.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Last reviewed: 31 July 2026