How Long Do You Take Wegovy For Weight Loss? | Cured

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Cheapest Wegovy Weight Loss - UK Price From £69.00

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£99 £79.00

£19.75 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £99
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy Oral Pill
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy Oral Pill
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy Oral Pill
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy Oral Pill
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

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How Long Do You Take Wegovy For Weight Loss?

Published on: June 03, 2026

Understanding how long do you take Wegovy for weight loss is essential before starting treatment. Most patients use Wegovy for a minimum of 12 months to achieve and maintain clinically significant weight reduction, though many continue long-term under prescriber supervision. At Cured Pharmacy, our UK-registered clinical team provides ongoing support throughout your weight management journey, with Wegovy available from £79.00 following a free online consultation.

How Long Do You Take Wegovy for Weight Loss: Clinical Evidence

The STEP clinical trial programme, which led to Wegovy's UK licensing by the MHRA, tracked patients for 68 weeks (approximately 16 months) and demonstrated sustained weight reduction throughout this period [1]. Participants who completed the full treatment duration achieved an average 14.9% body weight reduction, with most weight loss occurring during the first 60 weeks [1].

Clinical data shows that Wegovy works progressively rather than immediately. The medication requires a 16-20 week dose escalation phase to reach the full 2.4mg maintenance dose, during which your body gradually adapts to semaglutide whilst appetite suppression and metabolic effects build [2]. Stopping treatment before 12 months typically means patients haven't experienced the medication's full clinical benefit.

Long-term follow-up studies indicate that weight regain commonly occurs when Wegovy is discontinued, which is why many prescribers recommend ongoing treatment for sustained weight management rather than viewing it as a short-term intervention [3]. Your UK prescriber will review your progress at regular intervals to determine the optimal treatment duration for your individual circumstances.

Wegovy Dosing Schedule and Treatment Phases

Wegovy treatment follows a structured escalation protocol designed to minimise gastrointestinal side effects whilst building therapeutic efficacy. The standard UK dosing schedule begins at 0.25mg weekly for four weeks, then increases monthly through 0.5mg, 1mg, and 1.7mg doses before reaching the 2.4mg maintenance dose at week 17 [2].

This gradual escalation isn't optional—it's a clinical requirement that significantly reduces the risk of nausea, vomiting, and treatment discontinuation. Patients who attempt to accelerate the schedule typically experience more pronounced side effects and higher dropout rates [2].

Once you reach the 2.4mg maintenance dose, most patients continue at this level indefinitely, subject to ongoing prescriber review. Some individuals may require dose adjustments based on tolerability or clinical response, but the maintenance phase typically represents the remainder of your treatment duration, whether that's 12 months, 24 months, or longer [3].

What Happens During the Maintenance Phase

The maintenance phase begins once you've completed dose escalation and stabilised on 2.4mg weekly injections. During this period, weight loss typically continues at a slower rate than the initial months, and the focus shifts toward weight maintenance and preventing regain. Clinical trials showed that patients who remained on Wegovy during the maintenance phase maintained their weight loss, whilst those switched to placebo regained approximately two-thirds of their lost weight within one year [3].

How Long Should You Stay on Wegovy for Optimal Results

NICE guidance and clinical consensus suggest a minimum treatment duration of 12 months for patients who tolerate Wegovy and demonstrate clinical response, defined as at least 5% body weight reduction after 12 weeks on the maintenance dose [4]. However, optimal duration varies significantly between individuals based on weight loss goals, metabolic health improvements, and individual response.

Many patients continue Wegovy beyond the initial 12 months, particularly those managing obesity as a chronic condition rather than targeting a specific weight goal. Long-term data from extension studies tracking patients for up to 104 weeks (two years) show sustained weight reduction and metabolic benefits without significant safety concerns during extended use [3].

Your UK prescriber will assess several factors when determining your treatment duration: rate of weight loss, achievement of clinical targets, improvement in obesity-related comorbidities such as type 2 diabetes or hypertension, tolerability of side effects, and your personal weight management goals. Treatment is typically continued as long as you're experiencing clinical benefit and tolerating the medication appropriately.

When Prescribers May Recommend Stopping Wegovy

Discontinuation may be considered if you haven't achieved at least 5% weight reduction after six months on the maintenance dose, if you experience intolerable side effects that don't improve with dose adjustment, if you've reached and maintained your target weight for an extended period with established lifestyle changes, or if medical contraindications develop during treatment. These decisions are always made collaboratively between you and your prescriber rather than following a fixed timeline.

Treatment Active Ingredient Injection Frequency Typical Treatment Duration Starting Price
Wegovy Semaglutide 2.4mg Once weekly 12+ months (long-term) From £69.00
Saxenda Liraglutide 3mg Once daily 12+ months (long-term) From £68.00
Mounjaro Tirzepatide 15mg Once weekly 12+ months (long-term) From £124.99
Orlistat Orlistat 120mg Three times daily (oral) 6-12 months (short-term) From £32.00

Wegovy vs Other Weight Loss Treatments: Duration Comparison

Treatment duration expectations differ across weight loss medications licensed in the UK. Saxenda (liraglutide), an older GLP-1 receptor agonist requiring daily injections, typically follows similar long-term use principles to Wegovy, though clinical trials were shorter in duration and showed lower average weight reduction [5].

Orlistat, a lipase inhibitor available both on prescription and over the counter, is generally used for shorter durations of 6-12 months alongside dietary fat restriction. Unlike Wegovy, Orlistat works mechanically rather than hormonally and doesn't carry the same expectation of long-term use for weight maintenance [4].

Mounjaro (tirzepatide), the newest weight loss injection licensed in the UK, demonstrated even greater weight reduction than Wegovy in head-to-head trials, with treatment durations in clinical studies extending to 72 weeks [6]. Like Wegovy, tirzepatide is increasingly recognised as a long-term treatment rather than a temporary intervention.

What to Expect When Stopping Wegovy Treatment

Clinical evidence clearly demonstrates that weight regain is common after discontinuing Wegovy, even in patients who achieved significant weight loss during treatment. The STEP 4 withdrawal trial showed that participants who stopped Wegovy after 20 weeks of treatment regained approximately 6.9% of their body weight over the following 48 weeks, whilst those who continued treatment maintained their weight loss [3].

This weight regain occurs because semaglutide's appetite-suppressing and metabolic effects diminish once the medication clears from your system, which takes approximately 5-7 weeks given its long half-life. Without the medication's influence on GLP-1 receptors, hunger signals and metabolic rate tend to return toward pre-treatment levels unless substantial lifestyle modifications have been established and maintained [3].

If you and your prescriber decide to discontinue Wegovy, gradual dose reduction isn't typically necessary from a safety perspective, though some clinicians prefer a stepwise approach to help patients psychologically adjust. The focus should shift entirely to sustainable dietary patterns, regular physical activity, behavioural strategies, and potentially other weight management interventions to minimise regain. Regular follow-up with your healthcare team remains important during this transition period.

Strategies to Maintain Weight Loss After Stopping

Successful weight maintenance after discontinuing Wegovy requires establishing sustainable habits during treatment rather than relying solely on the medication's effects. Evidence-based strategies include maintaining a structured eating pattern with regular meal times, continuing food tracking or mindful eating practices developed during treatment, prioritising protein intake to preserve muscle mass and satiety, engaging in at least 150-300 minutes of moderate physical activity weekly, and maintaining regular weight monitoring to detect early regain. Some patients transition to other weight management medications or interventions rather than stopping treatment entirely.

Getting Started with Wegovy at Cured Pharmacy

At Cured Pharmacy, we understand that how long do you take Wegovy for weight loss is just one of many questions you'll have before starting treatment. Our UK-registered clinical team, led by Superintendent Pharmacist Tarun Kumar (GPhC 2233073), provides comprehensive support throughout your entire treatment journey, from initial consultation through dose escalation and long-term maintenance.

Your journey begins with a free online clinical assessment taking under three minutes, during which a UK prescriber reviews your medical history, current medications, weight loss goals, and suitability for Wegovy. If approved, your prescription is dispensed from our GPhC-registered pharmacy (9012511) and delivered in 100% discreet packaging directly to your door.

We offer transparent upfront pricing with Wegovy available from £79.00 per month, significantly lower than typical UK market rates. Unlike some providers, you'll see exact costs before completing your consultation, with no hidden fees or surprise charges. Our team remains available on (+44) 116 4646009 throughout your treatment for clinical questions, dose escalation guidance, or side effect management. Whether you use Wegovy for 12 months, 24 months, or longer, we're here to support your weight management success with genuine UK-licensed medication and expert pharmaceutical care.

Scientific References

  1. Wilding, J. P. H., Batterham, R. L., Calanna, S., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183 [accessed 13 August 2026]
  2. Novo Nordisk. (2023). Wegovy 2.4 mg Solution for Injection in Pre-filled Pen: Summary of Product Characteristics. Electronic Medicines Compendium. Retrieved from https://www.medicines.org.uk/emc/product/13799 [accessed 13 August 2026]
  3. Rubino, D., Abrahamsson, N., Davies, M., et al. (2021). Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA, 325(14), 1414–1425. https://doi.org/10.1001/jama.2021.3224 [accessed 13 August 2026]
  4. National Institute for Health and Care Excellence. (2023). Semaglutide for Managing Overweight and Obesity. NICE Technology Appraisal Guidance [TA875]. Retrieved from https://www.nice.org.uk/guidance/ta875 [accessed 13 August 2026]
  5. Pi-Sunyer, X., Astrup, A., Fujioka, K., et al. (2015). A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal of Medicine, 373(1), 11–22. https://doi.org/10.1056/NEJMoa1411892 [accessed 13 August 2026]
  6. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205–216. https://doi.org/10.1056/NEJMoa2206038 [accessed 13 August 2026]
  7. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 13 August 2026.
  8. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 13 August 2026.
  9. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 13 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Individual results may vary, and weight loss outcomes depend on multiple factors including adherence to treatment, lifestyle modifications, and individual metabolic response.

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Faq

How long do you take Wegovy for weight loss on average?
Most patients use Wegovy for a minimum of 12 months to achieve optimal results, though many continue long-term as it's increasingly recognised as an ongoing treatment for chronic weight management rather than a temporary intervention. Your UK prescriber will determine the appropriate duration based on your individual response and clinical goals.
Can you stop taking Wegovy once you reach your goal weight?
Whilst you can stop Wegovy after reaching your goal weight, clinical trials show that most patients regain approximately two-thirds of their lost weight within one year of discontinuation. Many prescribers recommend continuing treatment long-term to maintain weight loss, though this decision should be made collaboratively with your healthcare provider.
How long does it take for Wegovy to start working?
Most patients notice appetite reduction within 1-2 weeks of starting Wegovy, though significant weight loss typically becomes apparent after 8-12 weeks once you've progressed through the initial dose escalation phases. Maximum weight loss usually occurs between 60-68 weeks of continuous treatment.
Is Wegovy safe for long-term use beyond 12 months?
Clinical trial data extending to 104 weeks (two years) demonstrates that Wegovy maintains its safety profile during long-term use without significant new safety concerns emerging. Your UK prescriber will conduct regular reviews to monitor for any individual concerns during extended treatment.
What happens if I miss doses or stop Wegovy temporarily?
If you miss a Wegovy dose and it's been less than five days, take it as soon as possible; if more than five days have passed, skip that dose and resume your normal schedule. Extended breaks may require restarting the dose escalation schedule depending on how long you've been off treatment—consult your prescriber before resuming.
How long is the Wegovy dose escalation phase?
The standard Wegovy dose escalation takes 16-20 weeks to reach the full 2.4mg maintenance dose, starting at 0.25mg weekly and increasing monthly through 0.5mg, 1mg, and 1.7mg doses. This gradual approach significantly reduces gastrointestinal side effects compared to starting at higher doses.
Do I need to take Wegovy forever to maintain weight loss?
Not necessarily forever, though obesity is a chronic condition and many patients do continue long-term treatment. Some individuals successfully maintain weight loss after stopping by establishing sustainable lifestyle changes during treatment, whilst others experience regain and choose to resume medication—outcomes vary significantly between individuals.
How much does Wegovy cost for long-term treatment at Cured Pharmacy?
Wegovy is available from £79.00 per month at Cured Pharmacy, with transparent upfront pricing shown before your free consultation. For a 12-month treatment course, this represents significant savings compared to typical UK market rates, and we guarantee the lowest prices in the UK for genuine licensed medication.
Can I stop taking Wegovy once I reach my weight loss goal?
While you can stop Wegovy after reaching your goal, many people regain weight once they discontinue treatment. Cured Pharmacy recommends discussing a maintenance plan with your prescriber, as continued use at a maintenance dose often helps sustain long-term weight loss results.
How long should I wait to see weight loss results with Wegovy?
Most people begin to see noticeable weight loss within 4-8 weeks of starting Wegovy, with more significant results after 3-6 months of consistent use. Cured Pharmacy provides ongoing support throughout your Wegovy journey to help you achieve the best possible outcomes.
Is there a maximum time limit for how long you can take Wegovy?
There is no specific maximum time limit for Wegovy use, and many patients continue treatment long-term under medical supervision. Cured Pharmacy prescribers will monitor your health and weight loss progress to ensure Wegovy remains safe and effective for you over time.
Do I need to take Wegovy for weight loss forever to maintain results?
Long-term or indefinite use is often recommended to maintain weight loss, though some people successfully maintain results with lifestyle changes alone after stopping. Cured Pharmacy offers flexible treatment plans and prescriber consultations to help you find the best long-term approach for sustained weight management.
How long do you take Wegovy for weight loss to see results?
Most patients begin to see noticeable weight loss within 4 to 8 weeks of starting Wegovy, though individual results vary. For optimal and sustained weight loss, Wegovy is typically taken long-term as part of a comprehensive weight management plan that includes diet and exercise.
How long do most people stay on Wegovy for weight loss?
Clinical trials and real-world evidence suggest that Wegovy is most effective when used as a long-term treatment, often for 1 year or longer. Cured Pharmacy provides ongoing prescriber support to help you determine the right duration based on your individual health goals and response to treatment.
Is Wegovy cheaper at Cured Pharmacy than other UK pharmacies?
Yes, Cured Pharmacy offers Wegovy from £69 with an additional £20 off your first order using code WEIGHTLOSSNEW, making it one of the most affordable options in the UK. Our transparent pricing includes prescriber consultation and fast delivery with no hidden fees.
What happens if I need to take Wegovy for longer than 6 months?
Many patients safely continue Wegovy beyond 6 months to maintain weight loss and health improvements, with ongoing medical supervision. Cured Pharmacy provides regular prescriber reviews to ensure Wegovy remains safe and effective for you throughout your weight loss journey.
Can you stop taking Wegovy after reaching your target weight?
While you can stop Wegovy after achieving your weight loss goal, many patients regain weight once treatment ends. Clinical studies show that continuing Wegovy helps maintain weight loss long-term, and Cured Pharmacy can help you develop a personalised plan for your individual needs.
How long is it safe to take Wegovy for weight management?
Clinical trials have demonstrated Wegovy is safe for long-term use beyond 2 years when medically appropriate. Cured Pharmacy's UK-registered prescribers regularly review your treatment to ensure Wegovy remains suitable and effective for your weight loss journey.
Does the Wegovy price increase as you move up doses?
Yes, Wegovy pricing increases with higher doses, starting from £69 for 0.25mg up to £179 for the maintenance 2.4mg dose. Cured Pharmacy offers the cheapest UK prices across all Wegovy doses with transparent pricing and £20 off your first order using code WEIGHTLOSSNEW.
How long should you stay on each Wegovy dose before increasing?
You typically take each Wegovy dose for 4 weeks before increasing to the next strength, allowing your body to adjust and minimise side effects. Cured Pharmacy's prescribers guide you through the dosage escalation schedule to ensure safe and effective weight loss with Wegovy.
How long do you take Wegovy for weight loss results?
Most people take Wegovy for at least 3-4 months to see noticeable weight loss results, with optimal outcomes typically achieved after 12-16 months of continuous use. Cured Pharmacy supports long-term Wegovy treatment plans with convenient monthly subscriptions and ongoing clinical guidance.
Can I stop taking Wegovy after reaching my weight loss goal?
Stopping Wegovy after reaching your goal weight often leads to weight regain, as the medication works by regulating appetite and metabolism. Most healthcare professionals recommend continuing Wegovy long-term as a maintenance therapy, and Cured Pharmacy provides ongoing prescriber support to help you decide the best approach for your individual needs.
How long should I take Wegovy if I'm not losing weight?
If you haven't lost at least 5% of your starting weight after 3-4 months on the maintenance dose of Wegovy, your prescriber may recommend discontinuing treatment or exploring alternative options. Cured Pharmacy offers free follow-up consultations to review your progress and adjust your weight loss plan if needed.
Is it safe to take Wegovy for weight loss long-term?
Clinical trials have shown Wegovy is safe for long-term use beyond 2 years when prescribed and monitored appropriately by healthcare professionals. Cured Pharmacy ensures all patients receive ongoing clinical oversight throughout their Wegovy treatment journey to maintain safety and effectiveness.
Does the price of Wegovy increase the longer I take it?
Yes, Wegovy prices increase as you progress through higher maintenance doses, starting from £69 for the 0.25mg starter dose up to £179 for the 2.4mg maintenance dose. Cured Pharmacy offers transparent pricing at every dose level, plus £20 off your first order with code WEIGHTLOSSNEW to help make long-term treatment more affordable.
Can you stop taking Wegovy after reaching your weight loss goal?
While you can stop Wegovy after achieving your target weight, studies show many people regain weight once treatment ends. Most healthcare providers recommend continuing Wegovy long-term as a maintenance therapy to sustain weight loss results, though you should discuss your individual circumstances with your prescriber at Cured Pharmacy.
How long is it safe to take Wegovy for weight loss?
Clinical trials have demonstrated Wegovy is safe for long-term use, with patients taking it for 2+ years in studies without significant safety concerns. Wegovy is designed as a chronic weight management treatment, meaning it can be taken indefinitely under medical supervision, with Cured Pharmacy providing ongoing prescriber reviews to monitor your progress.
Does the duration you take Wegovy affect how much weight you lose?
Yes, the length of time you take Wegovy directly impacts total weight loss, with maximum results typically achieved after 12-18 months of continuous treatment. Patients who maintain Wegovy therapy long-term generally experience greater and more sustained weight loss compared to those who discontinue early, which is why Cured Pharmacy offers flexible subscription plans for ongoing treatment.
How long do you need to take Wegovy before increasing the dose?
Wegovy follows a structured dose escalation schedule, with each dose level taken for 4 weeks before increasing to the next strength. You'll start at 0.25mg for the first month, then progress through 0.5mg, 1mg, 1.7mg, and finally reach the maintenance dose of 2.4mg at week 17, ensuring your body adjusts gradually and minimising side effects throughout your weight loss journey.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 13 August 2026

Last updated on 13 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 13 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (13 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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