Buy Aciclovir Online UK from £4.49 | Cured Pharmacy

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Aciclovir Express Delivery - Order Online Today

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From £4.49 Starting dose — clinically approved
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Numark Cold Sore Cream - Aciclovir - UK-licensed prescription Treatment
Treatment

Numark Cold Sore Cream - Aciclovir

From £4.49

Future orders save 5%
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A
Treatment

Aciclovir - Cold Sore Treatment

From £19.99

Future orders save 5%
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Aciclovir Express Delivery - Order Online Today

Looking to buy aciclovir online UK pharmacy with fast, discreet delivery? Cured Pharmacy offers genuine UK-licensed aciclovir treatments from £4.49, with free clinical consultation and express delivery options. Our UK-registered prescribers assess your suitability within hours, ensuring you receive effective cold sore treatment quickly and safely.

How Aciclovir Works for Cold Sores

Aciclovir is an antiviral medication that specifically targets the herpes simplex virus (HSV-1), the primary cause of cold sores in the UK [1]. Once absorbed, aciclovir converts into its active form and blocks viral DNA replication, preventing the virus from multiplying and spreading to healthy cells.

Clinical studies demonstrate that when applied at the first sign of tingling or itching, aciclovir can reduce healing time by an average of 1-2 days and may decrease the severity of symptoms [1][2]. The medication works most effectively when treatment begins within the first 24-48 hours of symptom onset, though it can still provide benefit if started later in the outbreak cycle.

Aciclovir is available in two main formulations in the UK: topical cream (5% concentration) for external application directly to cold sores, and oral tablets (200mg or 400mg) for systemic treatment. Your UK prescriber will recommend the most appropriate formulation based on the frequency and severity of your outbreaks.

Aciclovir Cream vs Tablets: Choosing the Right Treatment

Aciclovir cream is typically the first-line treatment for occasional cold sore outbreaks in the UK. The 5% topical formulation works locally at the site of infection, minimising systemic exposure whilst delivering concentrated antiviral action directly to affected tissue [2]. Most patients apply the cream five times daily for 5-10 days, starting at the earliest sign of an outbreak.

Oral aciclovir tablets may be more appropriate for patients experiencing frequent recurrent outbreaks (more than six episodes per year) or severe symptoms. Systemic treatment provides higher drug concentrations in the bloodstream and can be used as suppressive therapy to reduce outbreak frequency [3]. The MHRA-approved dosing for cold sores is typically 200mg five times daily for five days, or 400mg three times daily as an alternative regimen.

At Cured Pharmacy, our UK-registered clinical team evaluates your outbreak history, symptom severity, and medical background during your free online consultation to determine which formulation offers optimal benefit. Superintendent pharmacist Tarun Kumar (GPhC 2233073) ensures all dispensed medications meet stringent UK quality standards.

When to Consider Suppressive Therapy

Patients experiencing six or more cold sore outbreaks annually may benefit from continuous suppressive therapy with oral aciclovir [3]. This approach involves taking a lower daily dose (typically 400mg twice daily) to maintain consistent antiviral levels and prevent viral reactivation. Clinical evidence shows suppressive therapy can reduce outbreak frequency by 70-80% in suitable patients, significantly improving quality of life for those with recurrent infections.

Express Delivery Options for Aciclovir in the UK

We understand that cold sore outbreaks require prompt treatment for maximum effectiveness. Cured Pharmacy offers multiple delivery options to ensure you receive your aciclovir treatment quickly and discreetly. All orders are dispatched from our UK-registered pharmacy premises in plain, unmarked packaging with no external indication of contents.

Standard delivery typically arrives within 2-3 working days via Royal Mail, whilst our express delivery service offers next-day delivery for orders placed before our daily cut-off time (subject to prescriber approval and stock availability). All prescription medications require completion of a brief online consultation with a UK-registered prescriber before dispatch — this typically takes under three minutes and most consultations are reviewed within hours during working days.

Your aciclovir prescription is processed by our GPhC-registered pharmacy team (registration number 9012511), ensuring full compliance with UK pharmaceutical regulations. We only dispense genuine UK-licensed medicines sourced through authorised wholesalers, guaranteeing authenticity and quality.

Product Type Application Starting Price
Numark Cold Sore Cream 5% aciclovir cream 5 times daily for 5-10 days From £4.49
Aciclovir Tablets 200mg/400mg oral 3-5 times daily for 5 days From £19.99

Aciclovir Dosage and Application Instructions

For topical aciclovir cream, the standard regimen involves applying a small amount (approximately pea-sized) to the affected area and surrounding skin five times daily, roughly every four hours during waking hours [2]. Treatment should begin at the first sign of tingling, itching, or redness, and continue for at least five days or until the cold sore has fully healed.

Oral aciclovir tablets for episodic treatment are typically prescribed as 200mg five times daily for five days, or alternatively 400mg three times daily for the same duration [3]. Tablets should be swallowed whole with water and can be taken with or without food. Maintaining adequate hydration during oral aciclovir treatment is important, particularly for patients with reduced kidney function.

Missing doses reduces treatment effectiveness, so setting reminders can help ensure consistent application or administration. If you miss a cream application, apply it as soon as you remember, then continue with your regular schedule. For oral tablets, take the missed dose when you remember unless it's nearly time for your next dose — never double up to compensate for forgotten doses.

Maximising Treatment Effectiveness

Clinical outcomes improve significantly when aciclovir treatment begins within 24 hours of symptom onset [1][2]. Keep a tube of aciclovir cream readily accessible if you experience recurrent outbreaks, allowing immediate application at the first tingling sensation. Wash hands thoroughly before and after application to prevent viral spread to other areas or individuals. Avoid touching or picking at cold sores, as this can prolong healing and increase infection risk.

Common Side Effects and Safety Considerations

Aciclovir is generally well-tolerated, with most side effects being mild and transient. Topical cream may occasionally cause temporary stinging, burning, or dryness at the application site in approximately 1-5% of users [2]. These local reactions typically resolve without intervention and rarely necessitate treatment discontinuation.

Oral aciclovir tablets can occasionally cause headache, nausea, or gastrointestinal discomfort in some patients [3]. Rare but serious side effects include allergic reactions (rash, itching, swelling) and, in patients with kidney impairment, potential effects on renal function. Your UK prescriber will review your medical history during consultation to identify any contraindications or necessary precautions.

Aciclovir is considered safe during pregnancy when clinically necessary, though you should always inform your prescriber if you are pregnant, planning pregnancy, or breastfeeding [4]. The medication passes into breast milk in small amounts, but is generally regarded as compatible with breastfeeding under medical supervision. Our clinical team at Cured Pharmacy carefully evaluates individual circumstances to ensure safe prescribing for all patient groups.

Why Choose Cured Pharmacy for Aciclovir Treatment

As a fully registered UK online pharmacy (GPhC 9012511), Cured Pharmacy combines clinical excellence with genuine value. Our transparent upfront pricing means you see the exact cost before completing your consultation — competitive UK pricing with no hidden fees or surprise charges at checkout.

Every prescription is reviewed by UK-registered prescribers who assess your suitability based on current MHRA guidance and clinical best practice. Our free online consultation takes under three minutes, with most consultations reviewed within hours during working days. You'll receive email updates throughout the process, from consultation approval through to dispatch confirmation with tracking details.

We guarantee 100% discreet packaging and only dispense genuine UK-licensed medications. Our customer service team is available on (+44) 116 4646009 during working hours to answer questions about your order, delivery, or treatment. Superintendent pharmacist Tarun Kumar (GPhC 2233073) personally oversees our clinical governance framework, ensuring every patient receives safe, effective treatment tailored to their individual needs.

Our Commitment to Patient Care

At Cured Pharmacy, we recognise that cold sore outbreaks can affect confidence and quality of life. Our service is designed to provide fast, professional access to effective treatment whilst maintaining the highest standards of pharmaceutical care. All consultations remain confidential, and our clinical team is available to provide ongoing support and advice throughout your treatment journey.

Scientific References

  1. Spruance, S. L., et al. (1997). Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrobial Agents and Chemotherapy, 41(7), 1594–1600. https://doi.org/10.1128/AAC.41.7.1594
  2. Spruance, S. L., et al. (2002). Peroral famciclovir in the treatment of experimental ultraviolet radiation-induced herpes simplex labialis: a double-blind, dose-ranging, placebo-controlled, multicenter trial. Journal of Infectious Diseases, 185(9), 1211–1218. https://doi.org/10.1086/339822
  3. Rooney, J. F., et al. (1993). Oral acyclovir to suppress frequently recurring herpes labialis. A double-blind, placebo-controlled trial. Annals of Internal Medicine, 118(4), 268–272. https://doi.org/10.7326/0003-4819-118-4-199302150-00004
  4. Pasternak, B., & Hviid, A. (2010). Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA, 304(8), 859–866. https://doi.org/10.1001/jama.2010.1206

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Faq

Can I buy aciclovir online UK pharmacy without seeing a GP?
Yes, aciclovir is available through online consultation with a UK-registered prescriber at Cured Pharmacy. You'll complete a brief clinical questionnaire that a qualified prescriber reviews before approving your prescription — no GP appointment necessary.
How quickly does aciclovir work for cold sores?
When applied within 24 hours of symptom onset, aciclovir can reduce healing time by 1-2 days on average. Most patients notice symptom improvement within 2-3 days of starting treatment, though complete healing typically takes 7-10 days.
Is aciclovir cream or tablets better for cold sores?
Aciclovir cream is typically suitable for occasional outbreaks and works locally at the infection site. Tablets may be more appropriate for frequent recurrent outbreaks (six or more per year) or severe symptoms, as they provide systemic antiviral coverage.
Can I use aciclovir if I'm pregnant or breastfeeding?
Aciclovir is generally considered safe during pregnancy and breastfeeding when clinically necessary. Always inform your prescriber of pregnancy or breastfeeding status during consultation so they can assess individual suitability and provide appropriate guidance.
How long does aciclovir express delivery take?
Express delivery typically arrives the next working day for orders placed before our daily cut-off time (subject to prescriber approval). Standard delivery takes 2-3 working days, with all orders dispatched in discreet, unmarked packaging.
Do I need a prescription to buy aciclovir online?
Yes, aciclovir is a prescription-only medication in the UK. Cured Pharmacy provides a free online consultation with UK-registered prescribers who assess your suitability before issuing a prescription — this typically takes under three minutes to complete.
What's the difference between aciclovir and over-the-counter cold sore treatments?
Aciclovir is an antiviral medication that directly inhibits HSV-1 replication, whilst many over-the-counter products only provide symptomatic relief. Clinical evidence demonstrates aciclovir reduces healing time more effectively than non-antiviral alternatives when started early.
Can I use aciclovir to prevent cold sores?
Yes, continuous suppressive therapy with oral aciclovir (typically 400mg twice daily) can reduce outbreak frequency by 70-80% in patients experiencing frequent recurrences. Your UK prescriber will assess whether suppressive therapy is appropriate based on your outbreak history.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Last reviewed: 17 July 2026