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Mounjaro vs Saxenda: UK Comparison & Discount Code

Published on: June 03, 2026

Searching for a mounjaro vs saxenda discount code uk offer? At Cured Pharmacy, you can save £20 on both treatments using code WEIGHTLOSSNEW, with Mounjaro starting from £124.99 and Saxenda from £135.00. Both are MHRA-licensed weight loss injections dispensed after a free clinical assessment by our UK-registered prescribers.

Mounjaro vs Saxenda: How They Work Differently

Mounjaro (tirzepatide) and Saxenda (liraglutide) are both injectable weight loss treatments licensed by the MHRA, but they work through fundamentally different mechanisms. Mounjaro is the UK's first dual GIP/GLP-1 receptor agonist, activating two distinct hormonal pathways that regulate appetite, blood sugar control, and energy expenditure [1]. Saxenda, by contrast, is a GLP-1 receptor agonist only, targeting a single pathway to suppress appetite and slow gastric emptying [2].

This dual-action mechanism gives Mounjaro a clinical advantage in head-to-head trials. In the SURPASS-2 study comparing tirzepatide directly with semaglutide (a similar GLP-1-only treatment to Saxenda), patients on the highest tirzepatide dose achieved an average 22.5% body weight reduction over 72 weeks, compared to 15.8% with semaglutide [1]. While Saxenda remains highly effective for many patients, particularly those seeking a lower starting price point, Mounjaro's dual mechanism may offer superior weight loss outcomes in clinical practice.

Both medications require subcutaneous injection, but their dosing schedules differ significantly. Mounjaro is administered once weekly via a pre-filled KwikPen, making it convenient for patients with busy lifestyles. Saxenda requires daily injections, which some patients find more burdensome but others prefer for gradual dose titration and flexibility [2].

Clinical Effectiveness: What the Trials Show

The SURPASS clinical trial programme evaluated tirzepatide across multiple doses and patient populations. In SURPASS-3, participants without diabetes achieved average weight reductions ranging from 15% to 22.5% depending on dose, with the 15mg weekly dose producing the greatest effect [1]. Importantly, 63% of patients on the highest dose achieved at least 20% body weight loss — a threshold associated with significant metabolic health improvements.

Saxenda's efficacy profile comes from the SCALE trials, which demonstrated an average 8% body weight reduction over 56 weeks in the SCALE Obesity and Prediabetes study [2]. While this is lower than Mounjaro's results, Saxenda has been available in the UK since 2017 and has a well-established safety profile. Many patients achieve clinically meaningful weight loss of 5-10%, which can significantly improve cardiovascular risk factors and quality of life.

It's crucial to understand that individual responses vary considerably. Some patients respond exceptionally well to Saxenda's GLP-1-only mechanism, while others may require the dual action of Mounjaro to achieve their weight loss goals. Your UK prescriber will consider your medical history, previous weight loss attempts, budget, and lifestyle factors when recommending the most appropriate treatment.

Real-World Outcomes Beyond Clinical Trials

Clinical trial data represents controlled conditions with highly motivated participants and regular monitoring. Real-world evidence suggests that adherence, lifestyle modifications, and ongoing clinical support significantly influence outcomes with both medications. At Cured Pharmacy, our clinical team provides ongoing guidance to help you maximise your treatment response, regardless of which medication you're prescribed.

Dosing, Administration & Treatment Schedules

Mounjaro treatment begins with a 2.5mg weekly injection for four weeks, allowing your body to adjust to the medication and minimising gastrointestinal side effects. Your prescriber will then increase the dose every four weeks, typically progressing through 5mg, 7.5mg, 10mg, 12.5mg, and potentially up to the maximum 15mg dose based on your response and tolerability [3]. Each dose comes in a colour-coded KwikPen for easy identification.

Saxenda follows a different titration schedule due to its daily administration. You'll start with 0.6mg daily for the first week, increasing by 0.6mg increments weekly until reaching the maintenance dose of 3mg daily [2]. This gradual escalation helps reduce nausea and other common side effects. Each Saxenda pen contains multiple doses, and you'll adjust the dose dial yourself according to your prescriber's instructions.

The injection technique is straightforward for both medications. You'll inject subcutaneously into your abdomen, thigh, or upper arm, rotating injection sites to prevent lipohypertrophy. Mounjaro's once-weekly schedule means you only need to remember one injection day per week — many patients choose the same day each week to establish a routine. Saxenda's daily schedule requires more frequent administration but allows for dose adjustments on shorter timescales if side effects occur.

Storage and Handling Requirements

Both medications require refrigeration before first use (2°C to 8°C). Once in use, Mounjaro pens can be stored at room temperature up to 30°C for up to 21 days, while Saxenda pens remain stable for 30 days. Never freeze either medication, and always check the solution is clear and colourless before injecting. Our pharmacy team provides detailed storage instructions with every dispensing.

Side Effects and Safety Considerations

Gastrointestinal side effects are the most commonly reported with both Mounjaro and Saxenda, including nausea, diarrhoea, constipation, vomiting, and abdominal discomfort. These effects typically occur during dose escalation and often diminish as your body adjusts to the medication [1][2]. In clinical trials, approximately 20-30% of patients experienced nausea with tirzepatide, compared to 40-50% with liraglutide, though severity and duration varied considerably.

More serious but rare side effects require immediate medical attention. Both medications carry warnings about pancreatitis, gallbladder disease, and potential thyroid C-cell tumours (based on rodent studies, though no causal link has been established in humans) [3][4]. You should not use either medication if you have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.

Hypoglycaemia risk is generally low with both treatments when used alone for weight loss, as neither medication causes insulin release in the absence of elevated blood glucose. However, if you're taking other diabetes medications or have impaired kidney function, your prescriber will need to adjust your treatment plan accordingly. Always report persistent vomiting, severe abdominal pain, or signs of allergic reaction to your healthcare provider immediately.

Cost Comparison and Discount Code Savings

At Cured Pharmacy, transparent pricing means you see the full cost before your clinical consultation. Mounjaro starts from £124.99 per pen, with the final price depending on your prescribed dose — higher doses naturally cost more due to the increased active pharmaceutical ingredient. Saxenda starts from £135.00 per pen, making it a more budget-friendly option for patients concerned about monthly treatment costs.

Using discount code WEIGHTLOSSNEW at checkout gives you £20 off your first order of either Mounjaro or Saxenda, reducing the financial barrier to starting treatment. This represents genuine savings on already competitive UK pricing. Remember that weight loss injections are an ongoing treatment — most patients continue for at least 6-12 months to achieve and maintain their target weight loss, so monthly costs are an important consideration.

When comparing costs, factor in the injection frequency. Mounjaro's once-weekly dosing means four injections per month, while Saxenda's daily regimen requires approximately 30 injections monthly (each pen lasts about six days at the 3mg maintenance dose). While Saxenda's per-pen price is lower, you'll need five pens monthly at the maintenance dose. Your prescriber will help you balance clinical effectiveness, convenience, and budget when selecting the most appropriate treatment.

What's Included in the Price

All prices at Cured Pharmacy include the free online clinical consultation with a UK-registered prescriber, the medication itself, and discreet home delivery. There are no hidden fees or consultation charges added at checkout. If your prescriber determines that weight loss medication isn't clinically appropriate for you, you won't be charged.

Who Can Use Mounjaro vs Saxenda in the UK

The MHRA has licensed Mounjaro for adults with a BMI of 30 kg/m² or above, or 27 kg/m² or above with at least one weight-related comorbidity such as hypertension, type 2 diabetes, or obstructive sleep apnoea [3]. Saxenda has identical BMI criteria and has been available in the UK since 2017 for chronic weight management [2]. Both medications are intended for use alongside a reduced-calorie diet and increased physical activity — they're not standalone solutions.

Certain medical conditions preclude the use of either medication. You cannot use Mounjaro or Saxenda if you're pregnant, planning pregnancy, or breastfeeding, as the effects on fetal development haven't been established. Both medications are also contraindicated in patients with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome. If you have severe gastrointestinal disease, inflammatory bowel disease, or diabetic gastroparesis, your prescriber will carefully evaluate whether these treatments are appropriate.

During your free online consultation at Cured Pharmacy, our UK-registered prescribers will review your complete medical history, current medications, and weight loss goals to determine which treatment — if any — is clinically suitable. This typically takes under three minutes to complete, and you'll receive a decision within hours. If prescribed, your medication ships discreetly to your UK address with next-day delivery options available.

Scientific References

1. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205–218. https://doi.org/10.1056/NEJMoa2206038 [accessed 13 August 2026]
2. Pi-Sunyer, X., Astrup, A., Fujioka, K., et al. (2015). A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal of Medicine, 373(1), 11–22. https://doi.org/10.1056/NEJMoa1411892 [accessed 13 August 2026]
3. Medicines and Healthcare products Regulatory Agency. (2023). Mounjaro 2.5 mg solution for injection in pre-filled pen: Summary of Product Characteristics. GOV.UK. https://www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency [accessed 13 August 2026]
4. European Medicines Agency. (2023). Saxenda (liraglutide): EPAR – Product Information. EMA. https://www.ema.europa.eu/en/medicines/human/EPAR/saxenda [accessed 13 August 2026]
5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 13 August 2026.
6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 13 August 2026.
7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 13 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Weight loss results vary between individuals, and outcomes cannot be guaranteed. Mounjaro and Saxenda are intended for use alongside a reduced-calorie diet and increased physical activity.