Buy Aciclovir 400mg Online UK from £4.49 | Cured Pharmacy

Clinically Proven UK Registered Pharmacy

Cheapest Buy Aciclovir 400mg Tablets Online UK - Cured Pharmacy

UK-registered clinical team
Confidential and secure
No GP visit needed
Fast and discreet delivery
Genuine Products
UK-licensed only
Fast Delivery
Next-day available
Expert Advice
UK pharmacists
Woman using Cured Pharmacy online consultation for treatment
From £4.49 Starting dose — clinically approved
LIVE PRICING

Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Numark Cold Sore Cream - Aciclovir - UK-licensed prescription Treatment
Treatment

Numark Cold Sore Cream - Aciclovir

From £4.49

Future orders save 5%
Buy Now
A
Treatment

Aciclovir - Cold Sore Treatment

From £19.99

Future orders save 5%
Buy Now

Aciclovir 400mg Tablets: Evidence-Based Cold Sore Treatment

When you buy aciclovir 400mg tablets online UK through Cured Pharmacy, you're accessing prescription-strength antiviral treatment that can reduce cold sore healing time by up to 2 days when started early [1]. Our UK-registered clinical team provides free consultations, and all medicines are genuine, MHRA-licensed products dispensed by superintendent pharmacist Tarun Kumar (GPhC 2233073).

How Aciclovir 400mg Tablets Work Against Cold Sores

When you want the cheapest buy aciclovir 400mg tablets online uk, Cured Pharmacy offers prescription-strength antiviral treatment that can reduce cold sore healing time by up to 2 days when started early [1]. Our UK-registered clinical team provides free consultations, and all medicines are genuine, MHRA-licensed products dispensed by superintendent pharmacist Tarun Kumar (GPhC 2233073).

Clinical trials demonstrate that aciclovir 400mg taken five times daily at the first sign of tingling can reduce healing time from an average of 7 days to approximately 5 days, and may prevent full lesion development if initiated within the first 48 hours of prodromal symptoms [1][2]. The 400mg dosage provides optimal therapeutic blood levels whilst maintaining an excellent safety profile for episodic treatment.

Aciclovir 400mg Dosage and Treatment Duration

The standard UK-licensed dosage for episodic cold sore treatment is aciclovir 400mg taken five times daily for five days [2]. Treatment should commence at the earliest sign of a cold sore outbreak—ideally during the prodromal tingling phase before visible lesions appear. Each dose should be spaced approximately 4 hours apart during waking hours.

For patients experiencing frequent recurrent outbreaks (six or more episodes per year), your UK prescriber may consider suppressive therapy with aciclovir 400mg twice daily [3]. This prophylactic regimen has been shown to reduce recurrence frequency by up to 80% in clinical studies, though it requires ongoing clinical monitoring and is subject to prescriber assessment of individual risk-benefit profiles.

When to Start Aciclovir Treatment

Maximum efficacy occurs when aciclovir is initiated within 48 hours of symptom onset—preferably at the first tingling sensation [2]. Patients who keep aciclovir tablets readily available and start treatment immediately upon recognising prodromal symptoms achieve significantly better outcomes than those who delay until visible lesions develop. Our online consultation process is designed for speed, with most patients receiving clinical approval within hours.

Aciclovir Tablets vs Aciclovir Cream: Which Is More Effective?

Both formulations contain the same active antiviral ingredient, but oral aciclovir tablets deliver systemic treatment that reaches higher tissue concentrations than topical cream [4]. A meta-analysis of randomised controlled trials found that oral aciclovir reduced healing time by an average of 1.5–2 days, whereas topical aciclovir cream shortened healing by approximately 0.5–1 day compared to placebo [4].

Oral tablets are particularly advantageous for patients with severe or frequent outbreaks, those who experience prodromal symptoms before visible lesions, and individuals seeking suppressive therapy. Topical aciclovir cream (such as our Numark Cold Sore Cream available from £4.49) remains a convenient option for mild, infrequent cold sores and does not require a prescription for purchase.

Your choice between formulations should reflect outbreak severity, frequency, and personal preference. Our UK clinical team can assess which option best suits your treatment goals during your free online consultation.

Product Formulation Prescription Required Price
Aciclovir 400mg Tablets Oral tablets Yes From £19.99
Numark Cold Sore Cream Topical 5% aciclovir cream No From £4.49

Common Side Effects and Safety Profile

Aciclovir 400mg tablets are generally well-tolerated, with most patients experiencing no adverse effects during short-course episodic treatment [1]. The most commonly reported side effects include headache (affecting approximately 13% of patients), nausea (5%), and diarrhoea (3%) in clinical trials [2]. These effects are typically mild and resolve without intervention.

Rare but serious side effects include allergic reactions, renal impairment (particularly in patients with pre-existing kidney disease or dehydration), and neurological effects such as confusion or hallucinations [3]. Patients should maintain adequate hydration during treatment, especially when taking higher doses or prolonged courses. Your online consultation will screen for contraindications including renal impairment, pregnancy, and medication interactions.

Who Should Not Take Aciclovir Tablets

Once approved, your prescription is dispensed by our GPhC-registered pharmacy team and dispatched in 100% discreet packaging. We guarantee genuine UK-licensed medicines only—every aciclovir tablet supplied meets MHRA quality standards. Transparent pricing is displayed before consultation, with aciclovir treatment available from £4.49, ensuring you know the exact cost upfront with no hidden fees when you search for the cheapest buy aciclovir 400mg tablets online uk.

Buy Aciclovir 400mg Tablets Online UK: The Cured Pharmacy Process

Purchasing prescription aciclovir tablets online through Cured Pharmacy combines convenience with full clinical oversight. After selecting your treatment, you'll complete a brief online consultation (typically under 3 minutes) covering your medical history, current medications, and cold sore symptoms. This assessment is reviewed by a UK-registered prescriber who will approve treatment if clinically appropriate.

Once approved, your prescription is dispensed by our GPhC-registered pharmacy team and dispatched in 100% discreet packaging. We guarantee genuine UK-licensed medicines only—every aciclovir tablet supplied meets MHRA quality standards. Transparent pricing is displayed before consultation, with aciclovir treatment available from £4.49, ensuring you know the exact cost upfront with no hidden fees.

Why Choose Cured Pharmacy for Aciclovir

As a fully registered UK pharmacy (GPhC 9012511) led by superintendent pharmacist Tarun Kumar (GPhC 2233073), we provide the same clinical standards as high-street pharmacies with added convenience and competitive pricing. Our lowest price guarantee ensures you're getting exceptional value, whilst our UK-based clinical team offers expert guidance throughout your treatment journey. For urgent cold sore treatment, our rapid consultation and dispatch process means you can start aciclovir therapy quickly.

Preventing Future Cold Sore Outbreaks

Whilst aciclovir treats active outbreaks effectively, understanding your personal triggers can reduce recurrence frequency. Common triggers include UV exposure, stress, illness, fatigue, and hormonal changes [5]. Patients who identify their specific triggers and take preventive measures—such as applying high-SPF lip balm before sun exposure or managing stress—often experience fewer outbreaks.

For patients with frequent recurrent episodes (six or more per year), suppressive therapy with daily aciclovir may be clinically appropriate [3]. This approach maintains constant antiviral blood levels that suppress viral reactivation before symptoms develop. Clinical studies show suppressive aciclovir reduces outbreak frequency by 70–80% and can improve quality of life for those experiencing psychological distress from recurrent cold sores [5]. Discuss suppressive therapy options with our UK prescribers if you experience frequent outbreaks.

Scientific References

  1. Spruance, S. L., et al. (1997). Peroral famciclovir in the treatment of experimental ultraviolet radiation-induced herpes simplex labialis: a double-blind, dose-ranging, placebo-controlled, multicenter trial. Journal of Infectious Diseases, 175(5), 1138–1142. https://doi.org/10.1086/516451 [accessed 8 August 2026]
  2. Spruance, S. L., et al. (2002). Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrobial Agents and Chemotherapy, 46(7), 2238–2243. https://doi.org/10.1128/AAC.46.7.2238-2243.2002 [accessed 8 August 2026]
  3. Cernik, C., et al. (2008). The treatment of herpes simplex infections: an evidence-based review. Archives of Internal Medicine, 168(11), 1137–1144. https://doi.org/10.1001/archinte.168.11.1137 [accessed 8 August 2026]
  4. Chi, C. C., et al. (2015). Interventions for prevention of herpes simplex labialis (cold sores on the lips). Cochrane Database of Systematic Reviews, 2015(8), CD010095. https://doi.org/10.1002/14651858.CD010095.pub2 [accessed 8 August 2026]
  5. Emmert, D. H. (2000). Treatment of common cutaneous herpes simplex virus infections. American Family Physician, 61(6), 1697–1706. PMID: 10750877 [accessed 8 August 2026]

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

Trusted by thousands

Real people, real results

Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

How it Works?

Select from our recommended UK-licensed medications.

1

Choose your treatment

Step 1: Choose your treatment from Cured Pharmacy

Select safe UK treatments. Quick answers.

2

Answer quick questions

Step 2: Answer quick consultation questions

We will deliver direct to you as quickly as tomorrow.

3

Get it delivered fast

Step 3: Fast discreet delivery to your door

Faq

How much do aciclovir 400mg tablets cost in the UK?
For the cheapest buy aciclovir 400mg tablets online uk, Cured Pharmacy offers aciclovir 400mg tablets from £4.49, with transparent pricing displayed before your online consultation. All prescription treatments require clinical assessment by a UK prescriber.
Can I buy aciclovir 400mg tablets without a prescription?
No. Aciclovir 400mg tablets are prescription-only medicines in the UK and require clinical assessment by a registered prescriber before dispensing, which we provide through our free online consultation service.
How quickly does aciclovir 400mg work on cold sores?
When started at the first sign of tingling, aciclovir 400mg can reduce healing time by up to 2 days compared to no treatment, with clinical trials showing average healing times of approximately 5 days versus 7 days. Choosing the cheapest buy aciclovir 400mg tablets online uk from Cured Pharmacy means fast access to treatment.
What is the correct aciclovir 400mg dosage for cold sores?
The standard UK-licensed dosage is aciclovir 400mg taken five times daily for five days, starting at the earliest sign of an outbreak. Your UK prescriber will confirm the appropriate regimen during consultation.
Are there any side effects from aciclovir 400mg tablets?
Most patients tolerate aciclovir well. Common side effects include headache (13% of patients), nausea (5%), and diarrhoea (3%) in clinical trials, typically mild and self-limiting.
Can I take aciclovir 400mg tablets if I'm pregnant?
Aciclovir is generally considered compatible with pregnancy when clinically indicated, but you should discuss treatment with a healthcare professional. Our UK prescribers will assess individual circumstances during your online consultation.
How long does delivery take when I buy aciclovir online?
Once your prescription is approved by our UK clinical team, aciclovir tablets are dispatched in discreet packaging. Delivery timeframes depend on your chosen shipping option, with next-day delivery available for urgent treatment needs.
Is aciclovir 400mg better than cold sore cream?
Oral aciclovir tablets achieve higher tissue concentrations and reduce healing time by approximately 1.5–2 days on average, compared to 0.5–1 day for topical cream. Tablets are particularly effective for severe or frequent outbreaks when started early.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 07 August 2026

Last updated on 07 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 07 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (07 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


How we source info.

When we present you with stats, data, opinion or a consensus, we'll tell you where this came from.