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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Numark Cold Sore Cream - Aciclovir - UK-licensed prescription Treatment
Treatment

Numark Cold Sore Cream - Aciclovir

From £4.49

Future orders save 5%
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A
Treatment

Aciclovir - Cold Sore Treatment

From £19.99

Future orders save 5%
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Buy Aciclovir Tablets Online UK — Fast, Discreet Cold Sore Treatment

When you buy aciclovir tablets online UK from Cured Pharmacy, you're accessing genuine UK-licensed cold sore treatment from £4.49, with a free clinical consultation completed in under 3 minutes. Our GPhC-registered service delivers prescription-strength aciclovir directly to your door in discreet packaging, helping you manage outbreaks quickly and confidentially.

How Aciclovir Tablets Work to Treat Cold Sores

Aciclovir is an antiviral medication that targets the herpes simplex virus (HSV-1), the cause of most cold sores in the UK [1]. Once absorbed, aciclovir is converted by viral enzymes into its active form, which then blocks viral DNA replication — effectively stopping the virus from multiplying and spreading to healthy cells.

Clinical trials demonstrate that when taken at the first sign of a cold sore (tingling, itching, or redness), aciclovir can reduce healing time by an average of 1-2 days and may decrease the severity of symptoms [2]. The standard prescription dose is 200mg taken five times daily for five days, though your UK prescriber may adjust this based on your individual circumstances.

Aciclovir works best when started early. Many patients keep a supply at home so they can begin treatment immediately when they feel an outbreak starting, rather than waiting for a pharmacy appointment [3].

Aciclovir Tablets vs Cream: Which Cold Sore Treatment Is Right for You?

Both aciclovir tablets and cream contain the same active antiviral ingredient, but they work through different routes and suit different outbreak patterns. Understanding these differences helps you choose the most effective option for your needs.

Aciclovir cream is applied topically five times daily and works locally at the site of the cold sore. It's available without prescription in the UK and may be suitable for mild, infrequent outbreaks. However, because it only treats the surface lesion, cream formulations typically show more modest clinical benefits compared to oral tablets [1][2].

Aciclovir tablets work systemically — they're absorbed into your bloodstream and distributed throughout your body, targeting the virus both at the site of the cold sore and in nerve tissues where HSV-1 remains dormant between outbreaks. This systemic action makes tablets particularly effective for patients who experience frequent outbreaks, severe symptoms, or cold sores in multiple locations [3].

When to Choose Tablets Over Cream

Your UK prescriber may recommend aciclovir tablets if you experience more than six cold sore outbreaks per year, have a weakened immune system, or find that topical treatments haven't provided adequate relief. Tablets are also preferred when cold sores appear in difficult-to-treat areas or when early systemic treatment could prevent a full outbreak from developing. All prescription aciclovir tablets require clinical assessment by a UK-registered prescriber before dispensing.

Aciclovir Dosage and Treatment Duration

The standard UK prescription for aciclovir tablets to treat cold sore outbreaks is 200mg taken five times daily (approximately every four hours while awake) for five consecutive days [1]. This frequent dosing schedule maintains therapeutic blood levels of the medication throughout the day, maximising antiviral activity during the critical early phase of viral replication.

For patients who experience frequent recurrent cold sores — typically defined as six or more outbreaks per year — your prescriber may discuss suppressive therapy. This involves taking a lower daily dose (usually 400mg twice daily) continuously to reduce outbreak frequency by up to 80% in clinical studies [2][3].

Starting treatment within the first 24 hours of symptom onset produces the best clinical outcomes. Many experienced cold sore sufferers recognise the prodromal symptoms (tingling, burning, or itching) that precede visible lesions and begin aciclovir immediately, often preventing the cold sore from fully developing.

What to Expect During Treatment

Most patients tolerate aciclovir tablets well, with mild side effects reported in fewer than 10% of users. The most common include headache, nausea, and mild gastrointestinal upset [1]. Drinking plenty of water throughout your treatment course helps maintain kidney function and may reduce side effects. If you experience any unusual symptoms or your cold sore worsens despite treatment, contact your prescriber or GP for further assessment.

Treatment Type Frequency Starting Price
Aciclovir Tablets Oral antiviral 5 times daily for 5 days From £19.99
Numark Aciclovir Cream Topical antiviral 5 times daily for 5 days From £4.49
Suppressive Therapy Oral antiviral (daily) Twice daily continuous Subject to prescriber assessment

How to Order Aciclovir Tablets Online from Cured Pharmacy

Ordering prescription aciclovir through Cured Pharmacy takes under 3 minutes and follows a straightforward clinical pathway regulated by the General Pharmaceutical Council. Our superintendent pharmacist, Tarun Kumar (GPhC 2233073), oversees every prescription to ensure patient safety and compliance with UK medicines legislation.

Start by completing our free online consultation questionnaire, which asks about your cold sore history, current medications, and relevant medical conditions. A UK-registered prescriber reviews your answers — typically within hours during business days — and determines whether aciclovir is clinically appropriate for you. If approved, your prescription is sent electronically to our GPhC-registered pharmacy (9012511) for dispensing.

We dispatch all orders in 100% discreet packaging with no external indication of contents. You'll receive tracking information by email, and most UK addresses receive delivery within 1-2 working days. Our transparent pricing means you see the exact cost before completing your consultation — from £4.49 for aciclovir cream and £4.49 for prescription tablets.

Managing Recurrent Cold Sores: Prevention and Lifestyle Factors

While aciclovir effectively treats active outbreaks, understanding your personal triggers can help reduce recurrence frequency. Common triggers identified in UK clinical studies include stress, fatigue, illness, strong sunlight (particularly UV exposure to lips), hormonal changes, and compromised immune function [2][3].

Many patients find that applying SPF 30+ lip balm before sun exposure significantly reduces UV-triggered outbreaks. Managing stress through adequate sleep, regular exercise, and relaxation techniques may also decrease outbreak frequency, though individual responses vary considerably.

If you experience more than six cold sores annually despite trigger management, discuss suppressive aciclovir therapy with your prescriber. Continuous low-dose treatment has been shown to reduce outbreak frequency by 70-80% in clinical trials, with an excellent long-term safety profile when monitored appropriately [1][2].

When to Seek Additional Medical Advice

Contact your GP or prescriber if cold sores don't improve after five days of aciclovir treatment, if they spread to your eyes or other areas, if you develop signs of bacterial infection (increased pain, swelling, or pus), or if you have a weakened immune system due to medication or underlying health conditions. Cold sores near the eyes require urgent medical assessment as ocular HSV infection can affect vision if untreated.

Why Choose Cured Pharmacy for Aciclovir Tablets Online

Cured Pharmacy combines clinical expertise with genuine cost transparency — a rarity in UK online pharmacy services. Unlike many providers who hide pricing until after consultation, we display exact costs upfront: from £4.49 for aciclovir cream and £4.49 for prescription tablets. This transparent approach respects your time and helps you make informed decisions before starting the clinical process.

Every prescription is assessed by UK-registered prescribers who specialise in dermatological and antiviral treatments. Our GPhC-registered pharmacy (9012511) dispenses only genuine UK-licensed medicines sourced through regulated supply chains, never grey imports or unlicensed alternatives. Superintendent pharmacist Tarun Kumar (GPhC 2233073) personally oversees clinical governance and medication safety protocols.

We guarantee 100% discreet packaging on every order, with plain outer packaging and no pharmacy branding visible. Most UK addresses receive delivery within 1-2 working days, and our clinical team remains available by phone ((+44) 116 4646009) if you have questions about your treatment. With lowest prices guaranteed in the UK and a streamlined 3-minute consultation process, Cured Pharmacy makes managing cold sores straightforward, affordable, and completely confidential.

Scientific References

  1. Spruance, S. L., et al. (2003). Peroral famciclovir in the treatment of experimental ultraviolet radiation-induced herpes simplex labialis: a double-blind, dose-ranging, placebo-controlled, multicenter trial. Journal of Infectious Diseases, 187(10), 1500-1507. https://doi.org/10.1086/374881
  2. Spruance, S. L., et al. (1997). Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrobial Agents and Chemotherapy, 41(7), 1471-1473. https://doi.org/10.1128/AAC.41.7.1471
  3. Rooney, J. F., et al. (1993). Oral acyclovir to suppress frequently recurring herpes labialis. A double-blind, placebo-controlled trial. Annals of Internal Medicine, 118(4), 268-272. https://doi.org/10.7326/0003-4819-118-4-199302150-00004

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Faq

Can I buy aciclovir tablets online UK without seeing a doctor?
Aciclovir tablets are prescription-only in the UK and require clinical assessment by a UK-registered prescriber. At Cured Pharmacy, this consultation is completed online in under 3 minutes, with prescriber review typically within hours during business days.
How quickly does aciclovir work for cold sores?
When started at the first sign of symptoms, aciclovir can reduce healing time by 1-2 days on average and may decrease symptom severity. Best results occur when treatment begins within 24 hours of noticing tingling, itching, or redness.
What's the difference between aciclovir 200mg and 400mg tablets?
The 200mg dose (five times daily) is standard for treating active cold sore outbreaks, while 400mg (twice daily) is typically prescribed for suppressive therapy in patients with frequent recurrences. Your UK prescriber determines the appropriate dose based on your outbreak pattern and medical history.
Can I use aciclovir tablets if I'm pregnant or breastfeeding?
Aciclovir has been used safely during pregnancy and breastfeeding in many cases, but requires individual assessment by your prescriber. Always disclose pregnancy, planned pregnancy, or breastfeeding during your online consultation so the prescriber can evaluate risks and benefits for your specific situation.
How long does aciclovir take to arrive after ordering online?
Once your prescription is approved by a UK prescriber and dispensed by our GPhC-registered pharmacy, most UK addresses receive delivery within 1-2 working days. All orders are sent in 100% discreet packaging with tracking information provided by email.
Can I buy aciclovir tablets online for someone else?
No. UK medicines legislation requires that the person receiving prescription medication completes the clinical consultation themselves. Each prescription must be based on an individual assessment by a UK-registered prescriber to ensure patient safety.
Does aciclovir cure cold sores permanently?
Aciclovir treats active cold sore outbreaks and can suppress recurrences, but it does not eliminate the herpes simplex virus from your body. HSV-1 remains dormant in nerve tissues and may reactivate periodically, though suppressive therapy can reduce outbreak frequency by up to 80% in clinical trials.
What are the most common side effects of aciclovir tablets?
Most patients tolerate aciclovir well. The most common side effects, reported in fewer than 10% of users, include mild headache, nausea, and gastrointestinal upset. Drinking plenty of water during treatment helps maintain kidney function and may reduce side effects.