Aciclovir Tablets Price UK from £4.49 | Cured Pharmacy

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Aciclovir Tablets Price UK - Online Prescription

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Numark Cold Sore Cream - Aciclovir

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Aciclovir - Cold Sore Treatment

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Aciclovir Tablets Price UK - Online Prescription

Published on: June 03, 2026

Searching for transparent aciclovir tablets price UK information? At Cured Pharmacy, you'll find genuine UK-licensed aciclovir tablets from £4.49, with upfront pricing displayed before your free clinical consultation. Our UK-registered prescribers assess your suitability in under 3 minutes, and we deliver discreetly to your door.

How Aciclovir Tablets Work for Cold Sores

Aciclovir is an antiviral medication that works by inhibiting viral DNA polymerase, preventing the herpes simplex virus (HSV-1) from replicating in infected cells [1]. When taken at the first sign of a cold sore outbreak — typically tingling or burning sensations — aciclovir can reduce healing time by approximately 1-2 days compared to untreated lesions [2].

The standard treatment regimen involves 200mg tablets taken five times daily for five days, though 400mg twice-daily dosing has shown comparable efficacy with improved adherence [1][3]. Clinical studies demonstrate that early intervention within 24-48 hours of symptom onset produces the best outcomes, with many patients experiencing reduced pain and faster crusting of lesions [2].

Aciclovir Tablets vs Cream: Which Treatment Is More Effective?

Both oral aciclovir tablets and topical aciclovir cream are licensed in the UK for cold sore treatment, but they work through different mechanisms and suit different clinical scenarios. Tablets provide systemic antiviral coverage, reaching the virus throughout your body, whilst cream offers localised treatment directly to the affected area.

Clinical evidence suggests oral aciclovir tablets may offer superior efficacy for frequent or severe outbreaks [3]. A systematic review published in the Journal of Antimicrobial Chemotherapy found that oral antiviral therapy reduced healing time more significantly than topical preparations, particularly when initiated early [4]. However, topical cream remains a practical first-line option for mild, infrequent cold sores and doesn't require a prescription for lower-strength formulations.

When to Choose Tablets Over Cream

Your UK prescriber may recommend oral aciclovir tablets if you experience more than six outbreaks annually, have severe symptoms, or possess a compromised immune system. Tablets are also preferred for suppressive therapy, where daily low-dose aciclovir can reduce outbreak frequency by up to 80% in clinical trials [1][3]. At Cured Pharmacy, our clinical team assesses your outbreak pattern and medical history to determine the most appropriate treatment approach during your free online consultation.

Understanding Aciclovir Tablets Price UK: What Affects Cost

Several factors influence aciclovir tablets price UK across different pharmacies, including tablet strength (200mg vs 400mg), pack size, and whether you're purchasing episodic treatment or long-term suppressive therapy. At Cured Pharmacy, we maintain transparent upfront pricing with no hidden consultation fees — you see the exact cost before completing your clinical assessment.

Our pricing structure reflects genuine UK-licensed medication dispensed by our GPhC-registered pharmacy (9012511), with prices typically lower than high-street alternatives. Unlike some providers who add substantial consultation charges or membership fees, we include your prescriber assessment at no additional cost, ensuring you only pay for the medication itself.

Prescription Requirements and Clinical Assessment

All aciclovir tablets in the UK require a prescription from a registered healthcare professional, as they're classified as prescription-only medicines (POM) by the MHRA. Our online consultation takes under 3 minutes and covers your medical history, current medications, and cold sore symptoms to ensure aciclovir is safe and appropriate for you. Superintendent pharmacist Tarun Kumar (GPhC 2233073) oversees all clinical assessments, maintaining the highest standards of pharmaceutical care.

Treatment Type Strength Prescription Required Starting Price
Aciclovir Tablets Oral antiviral 200mg/400mg Yes From £19.99
Aciclovir Cream 5% Topical antiviral 5% w/w No (OTC available) From £4.49

Aciclovir Dosing Schedules: Episodic vs Suppressive Therapy

Episodic therapy involves taking aciclovir only during active outbreaks, typically 200mg five times daily or 400mg twice daily for five days [1]. This approach suits patients with infrequent cold sores (fewer than six per year) and works best when treatment begins at the first tingling sensation, before visible lesions appear.

Suppressive therapy, conversely, involves daily aciclovir to prevent outbreaks altogether. Clinical trials show that 400mg twice daily can reduce recurrence rates by 70-80% in patients with frequent episodes [3][4]. This regimen is particularly valuable for individuals whose quality of life is significantly affected by recurrent cold sores, or those with immunocompromised status. Your UK prescriber will recommend the most suitable approach based on your outbreak frequency and lifestyle factors.

Common Side Effects and Safety Considerations

Aciclovir tablets are generally well-tolerated, with most patients experiencing minimal side effects. The most commonly reported adverse effects include headache (occurring in approximately 13% of patients), nausea, and mild gastrointestinal discomfort [1][2]. These symptoms are typically mild and resolve without intervention.

Rare but serious side effects may include allergic reactions, kidney function changes (particularly in patients with pre-existing renal impairment), or neurological symptoms such as confusion or tremors [2]. Adequate hydration whilst taking aciclovir helps minimise kidney-related risks. Your prescriber will review your renal function and adjust dosing if necessary, particularly for elderly patients or those with reduced kidney function. Always inform your healthcare provider if you're taking other medications, as aciclovir can interact with certain drugs including probenecid and mycophenolate mofetil.

Who Should Not Take Aciclovir Tablets

Aciclovir is contraindicated in patients with known hypersensitivity to aciclovir, valaciclovir, or any tablet excipients. Caution is required for pregnant or breastfeeding women, though aciclovir is generally considered safe when clinically necessary — it's classified as pregnancy category B by regulatory bodies [1]. Patients with severe kidney disease require dose adjustments, and elderly patients may need modified regimens due to age-related renal function decline. Your UK prescriber will assess all contraindications during your clinical consultation to ensure aciclovir is safe for your individual circumstances.

How to Order Aciclovir Tablets Online from Cured Pharmacy

Ordering aciclovir tablets through Cured Pharmacy is straightforward and clinically safe. Begin by completing our free online consultation, which takes under 3 minutes and covers essential medical history, current medications, and your cold sore symptoms. Our UK-registered prescribers review your assessment within hours, typically the same day for consultations submitted before 3pm.

Once approved, your prescription is dispensed by our GPhC-registered pharmacy and dispatched in 100% discreet packaging with no external branding. We offer next-day delivery options across the UK, ensuring you receive treatment quickly when you need it most. All medications are genuine UK-licensed products sourced through regulated channels, never grey-market imports. If you have questions at any stage, our clinical team is available on (+44) 116 4646009 during business hours.

What Happens After Your Consultation

If your prescriber determines aciclovir is suitable, they'll issue an electronic prescription directly to our pharmacy. You'll receive email confirmation with tracking details once your order is dispatched. Should aciclovir not be appropriate based on your medical history, our prescriber will explain why and may suggest alternative treatments such as topical aciclovir cream or other cold sore management strategies. We never charge for declined consultations, ensuring you only pay when treatment is approved and dispensed.

Scientific References

  1. Spruance, S. L., et al. (1996). Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials. Antimicrobial Agents and Chemotherapy, 40(5), 1246–1250. https://doi.org/10.1128/AAC.40.5.1246 [accessed 13 August 2026]
  2. Cernik, C., Gallina, K., & Brodell, R. T. (2008). The treatment of herpes simplex infections: An evidence-based review. Archives of Internal Medicine, 168(11), 1137–1144. https://doi.org/10.1001/archinte.168.11.1137 [accessed 13 August 2026]
  3. Rooney, J. F., et al. (1993). Oral acyclovir to suppress frequently recurring herpes labialis. A double-blind, placebo-controlled trial. Annals of Internal Medicine, 118(4), 268–272. https://doi.org/10.7326/0003-4819-118-4-199302150-00004 [accessed 13 August 2026]
  4. Chi, C. C., et al. (2015). Interventions for prevention of herpes simplex labialis (cold sores on the lips). Cochrane Database of Systematic Reviews, 2015(8), CD010095. https://doi.org/10.1002/14651858.CD010095.pub2 [accessed 13 August 2026]

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Faq

How much do aciclovir tablets cost in the UK?
Aciclovir tablets start from £4.49 at Cured Pharmacy, with transparent upfront pricing shown before your free consultation. Final cost depends on your prescribed strength and pack size, determined by your UK prescriber.
Can I buy aciclovir tablets without a prescription?
No. Aciclovir tablets are prescription-only medicines in the UK and require clinical assessment by a registered prescriber before dispensing, though lower-strength aciclovir cream is available over the counter.
How quickly do aciclovir tablets work for cold sores?
When taken at the first sign of symptoms, aciclovir tablets can reduce healing time by 1-2 days compared to untreated cold sores, with most patients noticing improvement within 24-48 hours of starting treatment.
What's the difference between 200mg and 400mg aciclovir tablets?
Both strengths are clinically effective — 200mg is typically taken five times daily, whilst 400mg is taken twice daily, offering equivalent efficacy with improved convenience and adherence.
Can I take aciclovir tablets every day to prevent cold sores?
Yes, suppressive therapy with 400mg twice daily can reduce outbreak frequency by 70-80% in clinical trials, and is recommended for patients experiencing six or more outbreaks annually.
Are aciclovir tablets safe during pregnancy?
Aciclovir is generally considered safe when clinically necessary during pregnancy (pregnancy category B), though you should always discuss this with your prescriber who will weigh benefits against potential risks.
How long does aciclovir tablets price UK delivery take?
Cured Pharmacy offers next-day delivery across the UK for orders approved and dispatched before our daily cut-off time, with all medications sent in 100% discreet packaging.
Do aciclovir tablets have side effects?
Most patients tolerate aciclovir well, with the most common side effects being mild headache (13% of patients) and nausea, which typically resolve without intervention.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 13 August 2026

Last updated on 13 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 13 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (13 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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