Does Mounjaro Cause Hair Loss? Side Effects, Causes, and Prevention Tips Explained

Mounjaro (tirzepatide) is a powerful injectable medication used to manage blood sugar in adults with type 2 diabetes—and more recently, it’s also being prescribed for weight loss. While it’s proven effective for both purposes, many users have raised a pressing concern: Does Mounjaro cause hair loss?

The short answer: hair loss is not a confirmed side effect of Mounjaro, but some users have reported it. Other medications in the same class—GLP-1 receptor agonists—have been associated with hair thinning or shedding, and rapid weight loss can also contribute to temporary hair loss. In this guide, we’ll explore what the evidence says, what might be causing hair shedding during treatment, and how to reduce or reverse it.

What Is Mounjaro and How Does It Work?

Mounjaro is the brand name for tirzepatide, a dual-action medication that activates two hormone receptors: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones help regulate blood sugar levels, reduce appetite, slow digestion, and increase feelings of fullness.

Originally approved to treat type 2 diabetes, Mounjaro has also shown significant weight loss effects in clinical trials. Its success in suppressing appetite and improving metabolic markers has led to its expanded use for weight management—even among people without diabetes.

It’s administered as a once-weekly injection with dosage increasing gradually from 2.5mg to 15mg to reduce side effects and allow the body to adjust.

Does Mounjaro Cause Hair Loss? What the Evidence Says

Officially, hair loss is not listed as a common side effect of Mounjaro in its FDA-approved prescribing information. However, anecdotal reports from patients suggest that some individuals may experience hair thinning or increased shedding while on the medication—especially after several months of use.

One meta-analysis involving over 8,000 Mounjaro users showed that about 4–5% experienced hair loss, compared to under 1% in the placebo group. While this doesn’t establish a direct cause, it has prompted further investigation. Related drugs like Zepbound, which also contain tirzepatide, have more clearly documented hair loss in post-marketing reports.

Hair Loss and GLP-1 Agonists: What We Know So Far

GLP-1 receptor agonists like Ozempic, Wegovy, and Saxenda have been widely used for diabetes and weight loss. Most do not list hair loss as an expected side effect, but it has still been reported by some patients. Zepbound—the weight loss version of Mounjaro—has formally added hair loss to its side effect list.

Here’s a quick comparison:

This suggests that while it’s uncommon, hair loss may be linked to individual response or rapid weight loss, rather than the drug itself.
Why Hair Loss May Happen on Mounjaro: The Possible Triggers

Even if Mounjaro isn’t directly causing hair loss, it could contribute indirectly. The most likely explanation is telogen effluvium—a condition where sudden physical stress (like significant weight loss or dietary changes) causes hair follicles to shift into a resting phase and shed more than usual.

Other contributing factors may include:

• Nutrient deficiencies (especially iron, zinc, biotin, vitamin D)

• Hormonal fluctuations triggered by weight loss

• Stress or illness

• Underlying conditions like PCOS, thyroid issues, or scalp disorders

Could Mounjaro Help Prevent Hair Loss in Some People?

Interestingly, some patients may actually see improved hair health while using Mounjaro—especially those with type 2 diabetes or PCOS, both of which are linked to hair thinning.

High blood sugar levels can reduce circulation to the scalp, leading to weaker follicles and slower growth. By improving blood sugar control, Mounjaro may help reverse this effect in some diabetic patients. Similarly, if weight loss from Mounjaro improves PCOS symptoms, it might also reduce hormonal hair loss.

Will My Hair Grow Back If I Stop Mounjaro?

If you’re experiencing hair loss on Mounjaro, you might be wondering if stopping the treatment will reverse it. In most cases—especially if the hair loss is due to telogen effluvium—the answer is yes. This type of shedding is typically temporary, and your hair can begin to grow back within 3–6 months after addressing the root cause.

That said, if your hair loss is tied to nutrient deficiencies, rapid weight loss, or another medical issue triggered during treatment, those factors must also be corrected to support regrowth. Stopping Mounjaro too soon may impact your weight loss or diabetes management, so always speak to your healthcare provider before discontinuing the medication. They may recommend nutritional blood tests or a slower transition to another treatment.

How to Reduce Hair Loss While Using Mounjaro

If you want to continue using Mounjaro but are concerned about hair thinning, there are several ways to minimise shedding and encourage hair regrowth:

Nutritional Support:

• Eat a balanced diet rich in iron, zinc, protein, biotin, and vitamins A, D, and E.

• Consider supplements if deficiencies are suspected, especially after rapid weight loss.

Scalp Health & Hair Growth Treatments:

• Apply Minoxidil (topical solution) to support regrowth.

• Try red light therapy or microneedling with a derma roller for follicle stimulation.

Lifestyle Adjustments:

• Reduce heat styling, harsh dyes, and tight hairstyles that cause traction.

• Get adequate sleep and manage stress with relaxation or gentle exercise.

• Avoid smoking and limit alcohol, as both can impact hair health.

Consistency is key—hair growth takes time, and early intervention offers the best chance of success.

Other Medications That May Cause Hair Loss

If you’re unsure whether Mounjaro is the cause of your hair loss, it’s worth reviewing any other medications you’re taking. Common drugs linked to hair shedding include:

• Antidepressants (e.g., fluoxetine, sertraline)

• Beta-blockers (e.g., propranolol, atenolol)

• Blood thinners (e.g., heparin, warfarin)

• Anticonvulsants, some antibiotics, and retinoids

• Other weight loss medications, such as Wegovy (in rare cases)

Hair loss may be listed as a rare side effect or appear after months of use. Always consult your GP or pharmacist to review possible causes.

When to See a Doctor or Trichologist About Hair Loss

Hair loss that lasts more than three months, worsens over time, or occurs in patches rather than all over the scalp may indicate an underlying condition. In these cases, you should consult a:

• GP or endocrinologist (to check hormone levels or thyroid function)

• Dermatologist (for scalp issues like psoriasis or seborrheic dermatitis)

• Trichologist (a hair and scalp specialist for more detailed assessment)

A thorough diagnosis might include blood tests, a scalp biopsy, or hair strand analysis to identify the exact cause.

Is Hair Loss a Reason to Stop Mounjaro? What to Discuss with Your Prescriber

For most people, mild hair shedding isn’t a reason to stop Mounjaro—especially if it’s delivering results for weight loss or blood sugar control. But if the side effect is severe, persistent, or emotionally distressing, it’s worth discussing with your healthcare provider.

They may:

• Recommend nutritional support or topical treatments

• Test for deficiencies or hormonal issues

• Adjust your dosage or suggest a drug holiday

• Explore alternative medications with fewer hair-related complaints

The key is to weigh the benefits of Mounjaro against the side effect’s impact on your overall well-being. Hair loss may be frustrating—but for many, it’s manageable and temporary with the right care.

Sources:

https://wimpoleclinic.com/blog/does-mounjaro-cause-hair-loss-expert-review/

https://www.medicalnewstoday.com/articles/drugs-mounjaro-and-hair-loss

https://medicalmojo.co.uk/does-mounjaro-cause-hair-loss/

https://www.gov.uk/government/news/mhra-authorises-diabetes-drug-mounjaro-tirzepatide-for-weight-management-and-weight-loss